Trial Outcomes & Findings for FOREward Together: Training Peer Recovery Coaches to Promote Retention and Adherence to MOUD (NCT NCT05098795)

Last Updated: 2025-03-14

Results Overview

Average number of days a participant missed an MOUD appointment between receiving the intervention and completing the follow-up assessment (approximately 8-12 weeks following the intervention date), averaged across all participants with available data.

Recruitment status

COMPLETED

Study phase

Target enrollment

29 participants

Primary outcome timeframe

Measured between participants' completion of baseline assessment and completion of the follow-up assessment (approximately 8-12 weeks following the intervention date).

Results posted on

2025-03-14

Participant Flow

Participants were enrolled via flyers and word-of-mouth at a community-based substance use treatment setting from December 2021 through April 2023.

Participant milestones

Participant milestones
Measure	Peer-delivered Behavioral Activation Adults 18 years or older on MOUD or referred to MOUD will receive Behavioral Activation (BA) an evidence-based intervention (EBI) by trained Peer Recovery Coaches (PRC) Behavioral Activation (BA): BA seeks to increase the positive reinforcement patients experience from their natural environment by promoting prosocial and valued experiences. BA has been found to improve substance use treatment retention and adherence, as well as medication adherence in low-income individuals with HIV/AIDS.
Overall Study STARTED	29
Overall Study Started BA	21
Overall Study Completed BA	13
Overall Study Completed Post-assessment	12
Overall Study COMPLETED	12
Overall Study NOT COMPLETED	17

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

FOREward Together: Training Peer Recovery Coaches to Promote Retention and Adherence to MOUD

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Peer-delivered Behavioral Activation n=29 Participants Adults 18 years or older on MOUD or referred to MOUD will receive Behavioral Activation (BA) an evidence-based intervention (EBI) by trained Peer Recovery Coaches (PRC) Behavioral Activation (BA): BA seeks to increase the positive reinforcement patients experience from their natural environment by promoting prosocial and valued experiences. BA has been found to improve substance use treatment retention and adherence, as well as medication adherence in low-income individuals with HIV/AIDS.
Age, Categorical <=18 years	0 Participants n=5 Participants
Age, Categorical Between 18 and 65 years	28 Participants n=5 Participants
Age, Categorical >=65 years	1 Participants n=5 Participants
Age, Continuous	46.6 Years STANDARD_DEVIATION 13.6 • n=5 Participants
Sex: Female, Male Female	10 Participants n=5 Participants
Sex: Female, Male Male	19 Participants n=5 Participants
Ethnicity (NIH/OMB) Hispanic or Latino	2 Participants n=5 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	26 Participants n=5 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	1 Participants n=5 Participants
Race (NIH/OMB) American Indian or Alaska Native	0 Participants n=5 Participants
Race (NIH/OMB) Asian	0 Participants n=5 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=5 Participants
Race (NIH/OMB) Black or African American	25 Participants n=5 Participants
Race (NIH/OMB) White	2 Participants n=5 Participants
Race (NIH/OMB) More than one race	0 Participants n=5 Participants
Race (NIH/OMB) Unknown or Not Reported	2 Participants n=5 Participants
Region of Enrollment United States	29 participants n=5 Participants

PRIMARY outcome

Timeframe: Measured between participants' completion of baseline assessment and completion of the follow-up assessment (approximately 8-12 weeks following the intervention date).

Population: We were able to get data on MOUD visits from 18 participants from the total sample.

Outcome measures

Outcome measures
Measure	Peer-delivered Behavioral Activation n=18 Participants Adults 18 years or older on MOUD or referred to MOUD will receive Behavioral Activation (BA) an evidence-based intervention (EBI) by trained Peer Recovery Coaches (PRC) Behavioral Activation (BA): BA seeks to increase the positive reinforcement patients experience from their natural environment by promoting prosocial and valued experiences. BA has been found to improve substance use treatment retention and adherence, as well as medication adherence in low-income individuals with HIV/AIDS.
MOUD Retention Rate	.42 number of days missed MOUD appointment Standard Deviation 2.86

PRIMARY outcome

Timeframe: The number of days between starting the intervention and completing the intervention (approximately 8-10 weeks).

Population: Fidelity was examined among participants who took part in at least one BA session.

Defined as the proportion of all 24 intervention components in the total intervention that were delivered with fidelity by the interventionist (ranging from 0 to 1.0 with higher proportion reflecting more fidelity).

Outcome measures

Outcome measures
Measure	Peer-delivered Behavioral Activation n=21 Participants Adults 18 years or older on MOUD or referred to MOUD will receive Behavioral Activation (BA) an evidence-based intervention (EBI) by trained Peer Recovery Coaches (PRC) Behavioral Activation (BA): BA seeks to increase the positive reinforcement patients experience from their natural environment by promoting prosocial and valued experiences. BA has been found to improve substance use treatment retention and adherence, as well as medication adherence in low-income individuals with HIV/AIDS.
Intervention Fidelity: Proportion of Intervention Components Delivered as Intended	.83 proportion of elements delivered Standard Deviation .09

SECONDARY outcome

Timeframe: The number of days between starting the intervention and completing the intervention (approximately 8-10 weeks).

Population: We examined the percentage of all participants who started the intervention who then completed the intervention (defined as taking part in 8 sessions)

Defined as the percentage of participants who started the intervention who then finish the intervention (defined as completing 8 total sessions)

Outcome measures

Outcome measures
Measure	Peer-delivered Behavioral Activation n=21 Participants Adults 18 years or older on MOUD or referred to MOUD will receive Behavioral Activation (BA) an evidence-based intervention (EBI) by trained Peer Recovery Coaches (PRC) Behavioral Activation (BA): BA seeks to increase the positive reinforcement patients experience from their natural environment by promoting prosocial and valued experiences. BA has been found to improve substance use treatment retention and adherence, as well as medication adherence in low-income individuals with HIV/AIDS.
Intervention Acceptability: Percentage of Patients Enrolled Who Attend ≥75% Sessions	62 percentage of participants

SECONDARY outcome

Timeframe: The number of days between starting providing consent and starting BA (approximately 1-5 weeks).

Population: We examined the percentage of participants who took part in at least one BA session relative to those who enrolled.

Defined as the percentage of participants who started BA sessions relative to those who enrolled in the program

Outcome measures

Outcome measures
Measure	Peer-delivered Behavioral Activation n=29 Participants Adults 18 years or older on MOUD or referred to MOUD will receive Behavioral Activation (BA) an evidence-based intervention (EBI) by trained Peer Recovery Coaches (PRC) Behavioral Activation (BA): BA seeks to increase the positive reinforcement patients experience from their natural environment by promoting prosocial and valued experiences. BA has been found to improve substance use treatment retention and adherence, as well as medication adherence in low-income individuals with HIV/AIDS.
Intervention Feasibility: Percentage of Patients Who Consents Who Started BA	21 Participants

Adverse Events

Peer-delivered Behavioral Activation

Serious events: 0 serious events

Other events: 0 other events

Deaths: 1 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Julia Felton

Henry Ford Health

Phone: 313-598-0841

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place