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Lung Health After Tuberculosis: Clinical and Functional Assessment in Post Pulmonary Tuberculosis Egyptian Patients.

NCT ID: NCT05097638

Last Updated: 2021-10-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

210 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-20

Study Completion Date

2020-02-04

Brief Summary

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Some of pulmonary tuberculous patients who completed their medication course experience lung function impairment

Detailed Description

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Some of pulmonary tuberculous patients who completed their medication course experience lung function impairment which may influence their quality of life. However, the pattern and nature of post-tuberculosis lung impairment is still not identified. Thus, the aim of this study was to determine the type and degree of lung physiology changes in previously treated tuberculous patients which latter may affect their quality of life; thus helping clinicians for early diagnosis of lung impairment, especially in tuberculous endemic areas.

Conditions

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Pulmonary Tuberculoses Pulmonary Function; Newborn, Abnormal

Keywords

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pulmonary Tuberculosis Spirometry Pulmonary Function

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cured pulmonary Tuberculosis patients

6 months after a completed course of anti-tuberculosis therapy

spirometry

Intervention Type DIAGNOSTIC_TEST

Patient do spirometry

Interventions

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spirometry

Patient do spirometry

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Patient completed an outpatient course of standard first line anti-tuberculosis therapy and declared as cured

Exclusion Criteria

* Smoker (to avoid spirometry biases).
* Extrapulmonary tuberculosis cases
* Multidrug resistant tuberculosis
* known contraindications to spirometry testing
* Individuals with chest wall deformities or neuromuscular diseases
* Patients who failed to achieve acceptability and reproducibility criteria of the spirometry test
* Defaulter cases or irregular treatment,
* known coexisting chronic lung disease as history of asthma or interstitial lung diseases
* A history of illicit drug use
* Patients with comorbidities: renal and hepatic insufficiency, heart diseases and metabolic disorders.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Nermeen Aly Mahmoud Abdel Aleem

Lecture in Chest and Tuberculosis Department, Faculty of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Chest Department-faculty of medicine-Assuit university

Asyut, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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5884

Identifier Type: -

Identifier Source: org_study_id