Digital Secondary Prevention in Cardiovascular Disease

NCT ID: NCT05096637

Last Updated: 2021-10-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

240 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-30

Study Completion Date

2023-07-31

Brief Summary

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Although advances in knowledge of the prevention, diagnosis and treatment of atherothrombosis are encouraging, cardiovascular diseases (CVD), with acute and chronic ischemic heart disease in particular, remain a major cause of disability and premature death throughout the world.

Cardiac rehabilitation (CR) and secondary prevention are coordinated multidimensional evidence-based strategies that aim to assist patients with acute and chronic ischemic heart disease return to an active and satisfying life and to prevent the recurrence of further cardiac events. Since CR is time limited after an acute event, secondary prevention proposes a continuum where care is provided for the rest of a person's life according to the existence of cardiovascular risk factors. Secondary prophylaxis is fundamental for the recovery of the patient, but in most cases, it is only insufficiently implemented.

To ensure adequate resources for the delivery of health care and to further improve the level of care, care-delivery models need to be changed in a way that patients themselves become more involved in their own care. Mobile health (mHealth) is a rapidly growing health delivery methodology with the potential to impact on health care research, health care delivery and health outcomes.

Therefore, the aim of the study is to determine the impact of plaque visualization using a digital intervention on treatment adherence to improve the cardiovascular risk profile. Participants will be randomized into two groups: intervention group and control group. Participants of the control group receive the best medical care according to current guideline recommendations without access to the app. Participants of the intervention group receive the best medical care according to current guideline recommendations with full access to the Smartphone application at time of study begin until the completion of the follow-up period of 12 months. The access to the app includes access to relevant findings including ultrasound images of the carotid artery, lipid profile, blood pressure values, and weight.

Detailed Description

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Conditions

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Atherosclerotic Plaque

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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control group

Patients receive the best medical care according to current guideline recommendations without access to the app

Group Type NO_INTERVENTION

No interventions assigned to this group

intervention group

Patients receive the best medical care according to current guideline recommendations with full access to the app. This includes access to relevant findings including ultrasound images of the carotid artery, lipid profile, blood pressure values, and weight.

Group Type EXPERIMENTAL

PreventiPlaque App

Intervention Type OTHER

PreventiPlaque is an app that supports patients with atherosclerotic plaque by strengthening their adherence.

Interventions

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PreventiPlaque App

PreventiPlaque is an app that supports patients with atherosclerotic plaque by strengthening their adherence.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Ultrasound evidence of atherosclerotic plaque in one or both carotid arteries
* Own a smartphone and know how to use apps
* presumed life expectancy of more than one year
* willing to comply with the protocol and provide written informed consent

Exclusion Criteria

* congestive heart failure with NYHA (New York Heart Association classification) III-IV symptoms
* severe valve disease
* no german knowledge
* unwillingness to user the app and/or undergo diagnostic procedures
Minimum Eligible Age

18 Years

Maximum Eligible Age

79 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Essen

OTHER

Sponsor Role lead

Responsible Party

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Julia Lortz

PD Dr. med.

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Ullrich G, Bauerle A, Jahre LM, Paldan K, Rosemeyer J, Kalaitzidis C, Rammos C, Teufel M, Rassaf T, Lortz J. Impact of visual presentation of atherosclerotic carotid plaque on cardiovascular risk profile using mHealth technologies. NPJ Digit Med. 2025 Jan 22;8(1):47. doi: 10.1038/s41746-024-01423-y.

Reference Type DERIVED
PMID: 39843925 (View on PubMed)

Other Identifiers

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20-9157-BO

Identifier Type: -

Identifier Source: org_study_id