Evaluation of Sublingual Microcirculation in Burn During Resuscitation
NCT ID: NCT05096559
Last Updated: 2021-10-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
30 participants
OBSERVATIONAL
2021-02-01
2022-02-01
Brief Summary
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Microcirculation camera will be placed on the base of the tongue and at different four quadrants. • Microcirculation parameters at baseline and after 8h , 16h and 24h of fluid resuscitation will be recorded. Fluid resuscitation with lactated ringer according to Parkland formula (4 ml/kg/%TBSA) 50% given during the first 8 hours, with the remainder given during the following 16 hours, will be initiated to maintain a urinary output of 0.5ml/kg/hr.Norepinephrine infusion will be started in case of circulatory failure at a rate of 0.02mic/kg/min to maintain MAP of 65-70mmHg.
Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Interventions
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Microcirculation cytocam
Visualization of tongue microcirculation
Eligibility Criteria
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Inclusion Criteria
* Burn \>20% TBSA
* Patients with burn admitted within the 1st 6 hours
Exclusion Criteria
* Pregnant patients.
* Patients with severe renal insufficiency.
* Patients shocked due to other causes as sepsis, hypovolaemia or cardiogenic shock
* Patients with airway edema that preclude the measurement of sublingual microcirculation
18 Years
ALL
No
Sponsors
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Cairo University
OTHER
Responsible Party
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Shymaa Fathy
Lecturer of anesthesia and SICU
Locations
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Kasr Al Ainy hospitals
Cairo, , Egypt
Countries
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Central Contacts
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Facility Contacts
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Shymaa Fathy
Role: primary
Other Identifiers
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N-111-2017
Identifier Type: -
Identifier Source: org_study_id