Effect of Physiological Ischemic Training on Patients With Atherosclerosis

NCT ID: NCT05091762

Last Updated: 2021-10-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-10-12

Study Completion Date

2025-12-31

Brief Summary

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To study whether the resistance training with blood flow obstruction in patients in early atherosclerosis period can produce a beneficial effect on preventing atherosclerosis.

Detailed Description

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Conditions

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Atherosclerosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Blank control group

Group Type NO_INTERVENTION

No interventions assigned to this group

Exercise group

Group Type EXPERIMENTAL

exercise

Intervention Type BEHAVIORAL

Upper limb resistance training with blood flow obstruction

Hyperlipidemia group

Group Type NO_INTERVENTION

No interventions assigned to this group

Hyperlipidemia and medication group

Group Type NO_INTERVENTION

No interventions assigned to this group

Hyperlipidemia and exercise group

Group Type EXPERIMENTAL

exercise

Intervention Type BEHAVIORAL

Upper limb resistance training with blood flow obstruction

Hyperlipidemia and medication and exercise group

Group Type EXPERIMENTAL

exercise

Intervention Type BEHAVIORAL

Upper limb resistance training with blood flow obstruction

Routine treatment group

Group Type NO_INTERVENTION

No interventions assigned to this group

Routine treatment and exercise group

Group Type EXPERIMENTAL

exercise

Intervention Type BEHAVIORAL

Upper limb resistance training with blood flow obstruction

Interventions

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exercise

Upper limb resistance training with blood flow obstruction

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. LDL \> 3.11mmol/l and less than 5.63mmol/l;
2. No serious heart, blood vessel and other related diseases;
3. There were no skeletal and muscular diseases affecting sports training;
4. No regular exercise in the past half year (no more than 2 times a week, no more than 30 minutes each time);
5. Smoking less than 1 pack / year, no history of drinking.

Exclusion Criteria

1. Haven't other serious heart and vascular diseases other than hyperlipidemia and / or bones and muscles that affect sports training Diseases;
2. Pregnant women and people with disabilities;
3. Other circumstances determined by the researcher not suitable for the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Nanjing First Hospital, Nanjing Medical University

OTHER

Sponsor Role lead

Responsible Party

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linaicui

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Aicui Lin, PhD

Role: STUDY_CHAIR

Nanjing First Hospital, Nanjing Medical University

Locations

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Nanjing First Hospital

Nanjing, Jiangsu, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Aicui Lin, PhD

Role: CONTACT

+8615305179718

JunXia Zhang, PhD

Role: CONTACT

+8615850770739

Facility Contacts

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Aicui Lin, PhD

Role: primary

+8615305179718

Other Identifiers

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KY20210604-02

Identifier Type: -

Identifier Source: org_study_id