Developpement of 3T MRI Protocol

NCT ID: NCT05090956

Last Updated: 2021-10-25

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 230 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2012-06-08
• Study Completion Date: 2020-01-29

Brief Summary

Since January 2010, a new magnetic resonance imaging scanner (Philips 3T, Achieva) is installed on the Baudot Building in Toulouse hospital. This tool, is completely dedicated to the research. It was installed with sequences RMN supplied by the manufacturer.

Imagers also contain an instrumentation susceptible to evolution and/or to adjustment (antennas radio frequency, sheath of gradients, elements of physiological monitoring (for example control of the breath), regulation of the homogeneity of the magnetic field).

This MRI scanner and this instrumentation are used for anatomical examinations or for paradigms of cognitiveresearch (for example of detection of intellectual activations following simple stimuli of fingers movement, visual tasks, or of mental processes).

The developpement of this equipment is going to favor the emergence of numerous projects and new themes, up to there adressed by other techniques (psychophysics, EEG).

To obtain good quality signals and know the practical limits of this imager, it is thus necessary that the researchers doctors, physicists and engineers, can finalize on volunteers' significant number, all the sequences RMN necessary for the use of these tools for the research.

These developments are going to get organized around four main axes:

1 the control of the geometrical distortions (generated by the introduction of an object within the magnetic field) 2 Optimization of the parameters of sequences to improve the contrast and the spatial resolution of the obtained images 3 the development of new sequences 4 the feasibility study of the protocols of functional MRI

Conditions

Healthy; Adult ALL; MRI

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

control

MRI exam; The sequences to be performed will be presented to the subject according to the focus to be performed. maximal duration of the exam: 2 hours (including subject set up)

Group Type: EXPERIMENTAL

mri

Intervention Type: OTHER

Interventions

mri

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

Healthy adult, age = 18 years;

• Visual, hearing , oral or written capacities and expression sufficient for the suitable realization of the tests;
• Obtaining of the informed consent of the subject.

Exclusion Criteria

• Subjects presenting a neurological, psychiatric history;
• Subjects under chronic medication which can influence the intellectual activity;
• Subjects presenting a contraindication to the MRI (carriers of a pacemaker, an implanted material(equipment) activated by an electric, magnetic or mechanical system, carriers of haemostatic clips of anévrysmes intracérébraux or carotid arteries, carriers of orthopaedic, claustrophobic implants);
• Subjects refusing to be informed about the possible presence of an anatomical anormality;
• administrative Problems: impossibility to give about the information, no insurance, refusal to sign the consent, under guardianship subject ;
• Subjects participating in another protocol • pregnancy

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Inserm U825

Toulouse, , France

Countries

France

Other Identifiers

2012-A00288-35

Identifier Type: REGISTRY

Identifier Source: secondary_id

C11-43

Identifier Type: -

Identifier Source: org_study_id