Socioeconomic Inequalities Exacerbated by Mitigation Measures to COVID-19 and Differences in Prematurity Prevalence

NCT ID: NCT05087160

Last Updated: 2021-10-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

37323 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-08-01

Study Completion Date

2021-09-30

Brief Summary

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Objective: to assess the perinatal results in Uruguay during the semester of successful control of the COVID 19 pandemic to evaluate the impact of the crises in the public and private sub sectors of the Health System.

Methodology: An analytical observational study was carried out, comparing the semesters from March 15 to September 30, 2019 (year prior to the COVID 19 pandemic) with the same period 2020 (year of the COVID 19 pandemic), in the 2 sub sectors of public and private health care.

Detailed Description

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An analytical observational study was carried out, comparing the semesters from March 15 to September 30, 2019 with the same period 2020, in the 2 sub sectors of public health care of the private sub sector throughout the country, taking all births in that period of time.

The semester selected is based on the fact that the first months of the pandemic were the ones with the greatest mitigation measures with drastic socio-economic consequences, but it was also a period of almost zero COVID infection in pregnancy, this being an opportune moment not to have as confounding factor to the maternal and fetal biological complications of this infection.

The situation will be analyzed in the 2 sub sectors of public health care, made up of the State Health Services Administration (ASSE), police health and military health, and the UDELAR Clinic Hospital, on the one hand, and the private sub-sector. made up of the Institutions of Collectivized Medical Assistance (IAMC) of Montevideo and the Interior (FEPREMI) and the private health care insurance.

The primary variable to be analyzed in both periods and in both subsectors of the national integrated system health was the incidence of preterm births (less than 37 weeks gestational age), low birth weight (newborns with a birth weight less than 2,500 grams) and intrauterine growth restriction (marked by doctor attending the birth, as a clinical diagnosis of the current pregnancy)

For the analysis of the national data, of the study periods, the database was requested from the Ministry of Public Health. This database is provided to researchers anonymously

Conditions

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COVID-19 Pandemic Preterm Low Birth-weight

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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semester pre pandemia in sub sectors of public health care in Uruguay

all birth in sub sectors of public health care between march 15 and September 30 of 2019, pre pandemia

No interventions assigned to this group

semester pre pandemia in sub sectors of private health care in Uruguay

all birth in sub sectors of private health care between march 15 and September 30 of 2019, pre pandemia

No interventions assigned to this group

semester with mitigation measures against COVID 19 in sub sectors of public health care in Uruguay

all birth in sub sectors of public health care between march 15 and September 30 of 2020, with mitigation measures against COVID- 19

mitigation measures against COVID 19

Intervention Type OTHER

no intervention

semester with mitigation measures against COVID 19 in sub sectors of private health care in Uruguay

all birth in sub sectors of private health care between march 15 and September 30 of 2020, with mitigation measures against COVID- 19

mitigation measures against COVID 19

Intervention Type OTHER

no intervention

Interventions

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mitigation measures against COVID 19

no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* all live birth

Exclusion Criteria

* stillbirth
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Universidad de la Republica

OTHER

Sponsor Role lead

Responsible Party

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Stephanie Viroga

Clinical professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Stephanie Viroga

Montevideo, , Uruguay

Site Status

Countries

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Uruguay

References

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Briozzo L, Tomasso G, Trujillo J, Viroga S, Pintos J, Nozar F, Aleman A, Buekens P. COVID-19 mitigation measures increase preterm birth and low birth weight in the public healthcare system in Uruguay. Int J Gynaecol Obstet. 2023 Aug;162(2):718-724. doi: 10.1002/ijgo.14778. Epub 2023 Apr 13.

Reference Type DERIVED
PMID: 37052316 (View on PubMed)

Other Identifiers

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COVID-19 and perinatal results

Identifier Type: -

Identifier Source: org_study_id