Arthroscopic Rotator Cuff Repair Utilizing Mechanical Bone Debridement Versus Coblation Debridement

NCT ID: NCT05084781

Last Updated: 2021-10-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

94 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-07-08

Study Completion Date

2025-06-30

Brief Summary

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Randomized controlled trial comparing coblation debridement to mechanical debridement in rotator cuff repair.

Detailed Description

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Prospective, Double blind, Randomized controlled trial. Male and female subjects, over the age of 18 years. Full thickness rotator cuff tear, requiring surgical repair. Patient undergoes pre- and intra-operative assessment, and once eligibility is confirmed intra-operatively, patient is randomly assigned to receive either a) coblation debridment, or b) mechanical debridement.

Standard post-operative rehab program for all patients. Follow-up occurs at 3, 6, 12, and 24 months post operatively and includes physical exam and patient based outcomes (questionnaires).

Conditions

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Rotator Cuff Tears

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Paralle study arms for 1)coblation debridement, 2) mechanical debridement
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors
Double blind - patient and outcome assessor.

Study Groups

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Coblation Debridement

FLOW 90 / WEREWOLF debridement of rotator cuff footprint.

Group Type EXPERIMENTAL

Coblation Debridement (FLOW90)

Intervention Type PROCEDURE

bipolar radiofrequency energy

Mechanical Debridement

Standard mechanical debridement of rotator cuff footprint.

Group Type ACTIVE_COMPARATOR

Coblation Debridement (FLOW90)

Intervention Type PROCEDURE

bipolar radiofrequency energy

Interventions

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Coblation Debridement (FLOW90)

bipolar radiofrequency energy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. The subject has signed the REB approved informed consent form (ICF) specific to this study prior to enrollment
2. The subject has a repairable full thickness rotator cuff tear with an estimated full thickness size \<5cm confirmed with diagnostic MRI in AP or ML dimension and /or ultrasound
3. The subject is independent, ambulatory, and can comply with all post-operative evaluations and visits
4. The subject has persistent pain and functional disability and has failed conservative treatment (e.g. PT, steroid injection, anti-inflammatory) for \> 3 months
5. The subject is at least eighteen (18) years of age and considered to be skeletally mature

Exclusion Criteria

1. The subject has undergone previous rotator cuff repair surgery to the affected shoulder
2. The subject has a partial thickness rotator cuff tear
3. The subject requires a concomitant labral repair
4. The subject has an irreparable rotator cuff tear
5. The subject is unable or unwilling to undergo MRI scan.
6. The investigator judges the subject unlikely to remain compliant to follow-up.
7. The subject has received an investigational therapy or approved therapy for investigational use within 30 days prior to the surgery
8. The subject is a prisoner, or is known or suspected to be transient
9. The subject's condition represents a worker's compensation case
10. The subject is currently involved in a health-related litigation procedure
11. The subject currently has an acute infection in the area surrounding the surgical site
12. The subject has a major medical illness (life expectancy less than 2 years or unacceptably high operative risk
13. Fatty atrophy \>50% (Goutallier grade 4-5)

INTRA-OPERATIVE EXCLUSIONS:

1. Massive or irreparable rotator cuff tear which cannot be mobilized to the midpoint of the footprint of the rotator cuff on the greater tuberosity
2. Co-existing labral pathology requiring repair with sutures
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Calgary

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ian Lo, MD FRSCS

Role: PRINCIPAL_INVESTIGATOR

University of Calgary

Locations

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Access Orthopaedics

Calgary, Alberta, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Ian Lo, MD FRCSC

Role: CONTACT

403-284-4062

Kristie More, MSc

Role: CONTACT

403-284-4062

Facility Contacts

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Kristie More, MSc

Role: primary

403-284-4062

Deanne Meredyk

Role: backup

403-284-4062

Other Identifiers

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REB19-1158

Identifier Type: -

Identifier Source: org_study_id