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Health and Aging Brain Study: Health Disparities Tau Positron Emission Tomography (PET) Scan Study

NCT ID: NCT05076331

Last Updated: 2021-10-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

3000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-04-20

Study Completion Date

2023-12-30

Brief Summary

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The purpose of this project is to study the aging brain among participants enrolled in the Health and Aging Brain Study: Health Disparities project . There are a number of things that can influence how people think as they age, including diabetes, depression, as well as our biology. In this study, the investigators seek to study the aging brain by using brain PET scans that create detailed pictures of the brain.

Detailed Description

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There are a number of things that can influence how we think as people age, including diabetes, depression, as well as our biology. In this study, the investigators are using PET scans with a tracer to create detailed pictures of the brain. This information will be used to help the investigators understand how the brain ages and in the future could be used to develop better diagnostics and treatments for Alzheimer's disease and memory loss in Mexican Americans, African Americans, and non-Hispanic whites. The goal of this study is to address this disparity by enrolling ethnically diverse participants in this study.

Conditions

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Alzheimer Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Health and Aging Brain Study Cohort

Health and Aging Brain Study participants age 50 and older.

PI-2620 tracer for Tau PET scan

Intervention Type DIAGNOSTIC_TEST

Tau PET scans are obtained using PI-2620 tracer provided by Life Medical Imaging.

Interventions

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PI-2620 tracer for Tau PET scan

Tau PET scans are obtained using PI-2620 tracer provided by Life Medical Imaging.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

1. Enrolled in the Health and Aging Brain Study HD: Health Disparities project
2. Provided consent to re-contact
3. Willing and capable of undergoing PET scan of the head

Exclusion Criteria

1. Inability to provide informed consent by self or by proxy.
2. Pregnant or breast feeding women\*
3. History of alcoholism or drug dependency/abuse within the last 2 years before screening
4. Hypersensitivity to the active substance or to any of the following excipients is contraindicated: sodium dihydrogen phosphate, phosphoric acid, sodium ascorbate, ethanol (anhydrous), water for injection
5. Participants may not be in this study if they do not meet the safety criteria to undergo imaging procedures.
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of North Texas Health Science Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University of North Texas Health Science Center

Fort Worth, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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2020-125

Identifier Type: -

Identifier Source: org_study_id