Non- Vs Partial Controlled Weightbearing After Multiple Knee Ligament Reconstruction

NCT ID: NCT05073276

Last Updated: 2024-11-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-01-01

Study Completion Date

2026-01-31

Brief Summary

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This is a prospective randomized controlled trial with the purpose to determine if patients undergoing isolated posterior cruciate ligament (PCL) reconstruction, or isolated medial collateral ligament (MCL) reconstruction, or combined PCL, anterior cruciate ligament (ACL), fibular collateral ligament (FCL), posterolateral corner (PLC), and MCL reconstructions (or any combination of multiple ligaments) can safely begin partial controlled weightbearing for the first six weeks after surgery.

Detailed Description

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Patients will be randomly assigned to one of two rehabilitation protocols for the first six weeks post-surgery:

1. non-weightbearing
2. partial weightbearing

An immobilizer brace in extension will be used from post-operative day 0 through 4 and a dynamic stabilizing posterior knee brace (Ossur) will be used from 5 days through 6 months post-surgery to protect against increased posterior translation forces due to gravity and while weightbearing for patients with PCL reconstructions.

Specific Aims

1. Primary Aim: To determine if there is clinical equivalence in millimeters of posterior tibial translation on posterior stress radiographs at six months post-surgery between patients who are non-weightbearing versus partial controlled weightbearing during the first six weeks of post-surgical rehabilitation.
2. Primary Aim: To determine if there is clinical equivalence in millimeters of valgus and/or varus compartment gapping on stress radiographs at six months post-surgery between patients who are non-weightbearing versus partial controlled weightbearing during the first six weeks of post-surgical rehabilitation.
3. Secondary Aim: To determine if there is a difference in pain, edema, range of motion, gait, and quadriceps strength between groups.

The current standard of care for posterior cruciate ligament reconstruction and multiligament reconstruction is non-weightbearing for the first six weeks after surgery.

Conditions

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Knee Injuries

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Non-weightbearing for the first six weeks after surgery

Not weightbearing after surgery

Group Type ACTIVE_COMPARATOR

Physical Therapy

Intervention Type OTHER

Patient is randomized to the weightbearing group the day after surgery.

Partial weight -bearing for the first six weeks after surgery

Partial weightbearing will be defined as 40% of the patient's body weight.

Group Type EXPERIMENTAL

Physical Therapy

Intervention Type OTHER

Patient is randomized to the weightbearing group the day after surgery.

Interventions

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Physical Therapy

Patient is randomized to the weightbearing group the day after surgery.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ≥ 14 years old, \<60
* Reconstruction of PCL alone
* Reconstruction of MCL alone
* Reconstruction of combined multiligament injuries (PCL+ (FCL, PLC, ACL, MCL))
* Reconstruction of multiligament injuries (ACL+MCL)
* Males or females
* Is willing and able to comply with the clinical trial plan and able to understand and sign the Patient Informed Consent Form.

Exclusion Criteria

* \< 14 years old
* \>60 years old
* Pregnant
* Revision PCL reconstructions
* Previous or concurrent vascular injury (vascular bypass procedure)
* Associated fractures requiring concurrent surgery
* Concurrent meniscal root or radial repair surgery
Minimum Eligible Age

14 Years

Maximum Eligible Age

59 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Twin Cities Orthopedics

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Robert F LaPrade, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Twin Cities Orthopedics

Locations

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Twin Cities Orthopedics

Edina, Minnesota, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Becky McGaver

Role: CONTACT

952-456-7136

Kayla Seiffert

Role: CONTACT

952-456-7085

Facility Contacts

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Becky Stone

Role: primary

952-456-7136

Robert F LaPrade, MD, PhD

Role: backup

Other Identifiers

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RFL_NWB vs PWB-Multi-Knee Lig

Identifier Type: -

Identifier Source: org_study_id

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