A Research Study Looking at How the Use of NovoPen® 6 for Treatment With Tresiba® & Fiasp® Affects the Blood Sugar Level in Patients With Type 1 Diabetes as Part of Local Clinical Practice

NCT ID: NCT05069545

Last Updated: 2025-12-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

411 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-11

Study Completion Date

2024-09-10

Brief Summary

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The purpose of this study is to collect information on how NovoPen® 6 works with Tresiba® \& Fiasp® for treatment of people with type 1 diabetes and see if the use of NovoPen® 6 can help participants achieve better blood sugar levels.

Participants will use Tresiba® \& Fiasp® in NovoPen® 6 as prescribed to participants by the study doctor.

NovoPen® 6 is a smart pen, which collects and stores the date and time of injections and number of units of insulin participants have taken.

NovoPen® 6 can transfer participants insulin dosing information to the mobile application, which participants use to see their continuous blood sugar level. This will allow participants to see their insulin doses along with continuous blood sugar level in the mobile application.

Participants will keep using their own continuous blood sugar monitoring device and the mobile application to see these data during the study.

The study will last for about 9-11 months. Participants will be asked to complete 2 questionnaires in this study. One questionnaire is about overall satisfaction of using a digital health solution and other is about quality of life. Participants will complete these questionnaires during their normally scheduled visit with the study doctor, on 2 separate occasions

Detailed Description

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Conditions

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Diabetes Mellitus, Type 1

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Tresiba + Fiasp using NovoPen 6 per local label

Participants will use Tresiba® and Fiasp® in NovoPen® 6 as prescribed to participants by the study doctor

Insulin degludec

Intervention Type DRUG

Introducing a NovoPen® 6 to patients with type 1 diabetes mellitus (T1DM), who are already being treated with Tresiba® and Fiasp®

Fast-acting insulin aspart

Intervention Type DRUG

Introducing a NovoPen® 6 to patients with type 1 diabetes mellitus (T1DM), who are already being treated with Tresiba® and Fiasp®

Interventions

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Insulin degludec

Introducing a NovoPen® 6 to patients with type 1 diabetes mellitus (T1DM), who are already being treated with Tresiba® and Fiasp®

Intervention Type DRUG

Fast-acting insulin aspart

Introducing a NovoPen® 6 to patients with type 1 diabetes mellitus (T1DM), who are already being treated with Tresiba® and Fiasp®

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Signed consent obtained before any study-related activities (study-related activities are any procedure related to recording of data according to the protocol).
* Male or female, age above or equal to 18 years at the time of signing consent.
* Diagnosed with T1DM (Type 1 Diabetes Mellitus) for above or equal to 1 year (365 days) at the time of signing consent.
* On treatment with Tresiba® for more than or equal to 1 month (30 days) and Fiasp® for for more than or equal to 3 months (90 days) at the time of signing consent.
* The decision to initiate the use of commercially available NovoPen® 6 as a part of treatment with Tresiba® and Fiasp® has been made by the patient/Legally Acceptable Representative (LAR) and the treating physician before and independently from the decision to include the patient in this study.
* Current user of a rtCGM (Real-Time Continuous Glucose Monitoring) or isCGM (Intermittent-scanning Continuous Glucose Monitoring) for greather than or equal to 2 months (60 days) of which the last 14 days must be on rtCGM or isCGM, which can integrate the data with diabetes treatment support solution from either Glooko or Abbott, at the time of signing consent.
* Willingness to continue using a rtCGM or isCGM for the duration of the study, which can integrate the data with diabetes treatment support solution from either Glooko or Abbott.
* Current user of a diabetes treatment support solution from either Glooko or Abbott, which can integrate the NovoPen® 6 injection data and the rtCGM/isCGM data, and willingness to continue using the same solution for the duration of the study.

Exclusion Criteria

* Previous participation in this study. Participation is defined as having given consent in this study.
* Treatment with any investigational drug within 30 days prior to enrolment into the study.
* Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation.
* Use of any smart pen or smart cap for the diabetes treatment prior to the signing consent.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Novo Nordisk A/S

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clinical Transparency (dept. 1452)

Role: STUDY_DIRECTOR

Novo Nordisk A/S

Locations

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Imeldaziekenhuis - Bonheiden - Department of Endocrinology

Bonheiden, , Belgium

Site Status

HUB - Hôpital Erasme

Brussels, , Belgium

Site Status

Cliniques Universitaires Saint-Luc - Serv Endocrinologie - Diabétologie

Brussels, , Belgium

Site Status

UZA - UZ Antwerpen - Department of Endocrinology

Edegem, , Belgium

Site Status

UZ Leuven - Endocrinology

Leuven, , Belgium

Site Status

Centre Hospitalier Universitaire de Liège

Liège, , Belgium

Site Status

Aarhus Universitetshospital Diabetes og Hormonsygdomme

Aarhus N, , Denmark

Site Status

Bispebjerg Hospital, IC-Forskning

Copenhagen, , Denmark

Site Status

Medicinsk Afdeling B, Herning Centralsygehus

Herning, , Denmark

Site Status

Regionshospitalet Silkeborg - Endokrinologisk afd.

Silkeborg, , Denmark

Site Status

Centre Hospitalier Universitaire de Caen Normandie- Cote de Nacre

Caen, , France

Site Status

Centre Hospitalier Sud Francilien

Corbeil-Essonnes, , France

Site Status

hôpital Saint Joseph Saint Luc

Lyon, , France

Site Status

Centre Hospitalier Universitaire de Montpellier-Hopital Lapeyronie

Montpellier, , France

Site Status

Ap-Hp-Hopital Bichat-Claude Bernard-1

Paris, , France

Site Status

Hospices Civils de Lyon-Hopital Lyon Sud-2

Pierre-Bénite, , France

Site Status

Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-2

Toulouse, , France

Site Status

Chru de Nancy - Hopital Brabois

Vandœuvre-lès-Nancy, , France

Site Status

Diabetesmottagningen, Medicinkliniken, Södra Älvsborgs Sjukhus

Borås, , Sweden

Site Status

Diabetesmottagningen, Södra Älvsborgs Sjukhus

Borås, , Sweden

Site Status

Endokrinologiska kliniken, Malmö

Malmo, , Sweden

Site Status

Medicinmottagning1 Universitetssjukhuset Örebro

Örebro, , Sweden

Site Status

Centrum for Diabetes, Academical Specialist Centrum

Stockholm, , Sweden

Site Status

Medicinkliniken Sundsv

Sundsvall, , Sweden

Site Status

Uppsala universitetssjukhus

Uppsala, , Sweden

Site Status

Frölunda Specialistsjukhus

Västra Frölunda, , Sweden

Site Status

Countries

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Belgium Denmark France Sweden

Other Identifiers

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U1111-1255-5564

Identifier Type: OTHER

Identifier Source: secondary_id

DV3325-4759

Identifier Type: -

Identifier Source: org_study_id