Efficacy and Safety of AP Collagen Peptide on the Skin

NCT ID: NCT05059197

Last Updated: 2021-11-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-12-15

Study Completion Date

2021-10-12

Brief Summary

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This double-blinded, randomized, placebo-controlled study aimed to evaluate the efficacy and safety of AP collagen peptides (APCP) containing 3% Glycine-Proline-Hydroxyproline (GPH) on improving skin health. Subjects with dried skin were randomly assigned to receive placebo or APCP once daily for 12 weeks.

Detailed Description

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Conditions

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Dry Skin

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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AP collagen peptide

Each subject takes one active bottle per day for 12 weeks. Each bottle contains AP collagen 1000 mg

Group Type EXPERIMENTAL

AP collagen peptide

Intervention Type DIETARY_SUPPLEMENT

Health functional food

Placebo

Each subject takes one active bottle per day for 12 weeks.

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

placebo

Interventions

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AP collagen peptide

Health functional food

Intervention Type DIETARY_SUPPLEMENT

Placebo

placebo

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Those whose eye wrinkles are Grade 3 or higher in the visual evaluation
* Those whose moisture retention in both cheeks measured by Corneometer® is 49 A.U. or less
* A person who has agreed to participate in this human application test before the start of the human application test and filled out the Informed Consent Form

Exclusion Criteria

* Those with skin diseases such as atopic dermatitis and psoriasis
* Those who are sensitive to or allergic to the food ingredients for this trial foods
* Those with skin abnormalities such as spots, acne, erythema, and hypersensitive skin at the test site
* People who take diet pills (absorbent and antidepressants, appetite suppressants, etc.) and contraceptives or hormones or diuretics within one month based on visit1
* Those who have used functional cosmetics for wrinkle improvement, highly moisturizing cosmetics, or skincare devices within 2 weeks of visit 1
* A person who used steroid-containing outer skin for more than one month to treat skin diseases
* A person who has received chemical and physical treatment (pattern, epidermis, lasers, procedures, etc.) in the test area within six months prior to the start of the test
* Visit 1 A person who has participated in other interventional clinical tests (including human application tests) within one month of the standard or plans to participate in other interventional clinical tests (including human application tests) after the start of this human application test
* A person who judges that the tester is inappropriate for this test
Minimum Eligible Age

35 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Amorepacific Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hae Kwang Lee, PhD

Role: PRINCIPAL_INVESTIGATOR

P&K Skin Research Center

Locations

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P&K Skin Research Center

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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PNK-20D21-FF1R

Identifier Type: -

Identifier Source: org_study_id