First Line Dose-efficacy Study of Bactecal® D Liquid for Infant Colic

NCT ID: NCT05052476

Last Updated: 2023-11-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

68 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-08

Study Completion Date

2023-10-16

Brief Summary

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This randomized, open label, dose-response study will be realized at the first line with Bactecal® D Liquid. The objective is to investigate Bactecal® D Liquid in the context of infantile colics.

The patients will be randomized into two arms, A and B, in function of the intervention dose. The quality of life of te parents as well as the daily median crying time and the number of daily crying will be assessed.

Detailed Description

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Conditions

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Colic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Open label Bactecal® D Liquid 1 dose

Patients will receive 1 dose of Bactecal® D Liquid by day which corresponds to 2 ml of product

Group Type EXPERIMENTAL

Bactecal® D Liquid

Intervention Type DIETARY_SUPPLEMENT

The patients will be randomized into two arms, A and B, in function of the intervention dose

Open label Bactecal® D Liquid 2 doses

Patients will receive 2 doses of Bactecal® D Liquid by day which correspond to 4 ml of product.

Group Type EXPERIMENTAL

Bactecal® D Liquid

Intervention Type DIETARY_SUPPLEMENT

The patients will be randomized into two arms, A and B, in function of the intervention dose

Interventions

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Bactecal® D Liquid

The patients will be randomized into two arms, A and B, in function of the intervention dose

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Full term healthy infant (37-41 weeks amenorrhea)
* Birth weight \>2750 g
* Aged between 2 and 8 weeks
* Presenting symptoms of infant colic as defined by Rome IV criteria by Zeevenhoven et al. 2017
* Signed written informed consent of the parent/tutor

Exclusion Criteria

* Premature birth
* Using probiotics as a treatment, different from the one that could contain the formula at the time of study recruitment
* Acute or chronic illness as judged by the investigator which avoids the participation to the study .
* Parents unable to understand the requirements of study participation as judged by the investigator
* Malnutrition as judged by a body weight/height ratio \<5 %
Minimum Eligible Age

2 Weeks

Maximum Eligible Age

8 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Astel Medica

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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UZ Brussel

Brussels, , Belgium

Site Status

Countries

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Belgium

Other Identifiers

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BACTECOLIC

Identifier Type: -

Identifier Source: org_study_id