Effect of Corticosteroid Injections on Blood Glucose

NCT ID: NCT05048264

Last Updated: 2025-03-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

38 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-04

Study Completion Date

2024-09-16

Brief Summary

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The purpose of this study is to measure the effect of various corticosteroids administered to the shoulder, knee and hip joints in diabetic patients on resultant blood glucose readings.

Detailed Description

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The purpose of this study is to measure the effect of various corticosteroids administered to the shoulder, knee, and hip joints in diabetic patients on resultant blood glucose readings.

Corticosteroid injections (CSI) are frequently used in orthopedic settings in order to treat a wide array of orthopedic issues, including osteoarthritis, bursitis, tendinitis, and many others. The effect of diabetes on the musculoskeletal system and its role in orthopedic disease has been well-documented. Current evidence demonstrates that corticosteroids, even when administered through a local musculoskeletal injection, can lead to temporary increases in blood glucose. Ultrasound guidance was not explicitly used in any of the studies examining the impact of steroids on blood glucose. The utilization of ultrasound guidance has been shown to increase accuracy when performing injections into the subacromial space as well as the glenohumeral joint when compared to palpation/landmark-guided injections.

Conditions

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Diabetes Mellitus Steroid Diabetes Shoulder Osteoarthritis Knee Osteoarthritis Adhesive Capsulitis Hip Osteoarthritis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Diabetic patients receiving a corticosteroid injection of their shoulder, knee or hip joints.

There are no study-related interventions for this study.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Known diabetic patients ages 40-75 undergoing clinically indicated standard of care corticosteroid shoulder, knee and hip joint injection
* Ability to perform daily blood glucose testing
* Can receive and send text messages

Exclusion Criteria

* Previous joint arthroplasty
* Corticosteroid injection at other sites in the body within the past month
* Systemic corticosteroid within the last month other than asthma inhaler
* Anyone who are unable to read and/or understand English
* Pregnant women (self-report)
Minimum Eligible Age

40 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Duke University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anthony Ceraulo, MD

Role: PRINCIPAL_INVESTIGATOR

Duke University

Locations

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Duke Sports Science Institute

Durham, North Carolina, United States

Site Status

Countries

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United States

Other Identifiers

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Pro00108093

Identifier Type: -

Identifier Source: org_study_id

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