Impact Of Post-Bariatric Body Contouring Procedures on Patient Body Weight and Metabolism

NCT ID: NCT05034081

Last Updated: 2024-08-20

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 60 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-09-01
• Study Completion Date: 2024-08-15

Brief Summary

Is post-bariatric body contouring surgery prevent weight regain or no, and what is the effect on the patient's Metabolism? Few literature studies report body contouring surgery to be positively associated with maintained weight loss after obesity surgery but the measures of outcomes are diverse, and the collective magnitude of such an association is unknown.

The changes in gastrointestinal hormones, adipokines, and cytokines as well as in hypothalamic neuropeptides and neurotransmitters resemble the changes observed in the anorexia/cachexia, suggesting that bariatric surgery triggers a catabolic state responsible for loss of appetite and prolonged body weight reduction.

Weight regain after gastric bypass surgery occurs in about half of all patients within 2 years. About 50% of patients eventually gain a little weight back after hitting their low point. We need a more thorough evaluation to determine what factors - medical, psychological, lifestyle - are involved in the weight gain. One of the factors that seem to be responsible for the degree and durability of weight loss is post-bariatric body contouring procedures. However, metabolic consequences of removing excess subcutaneous adipose tissue by body contouring procedures have to a lesser extent been explored

Conditions

Bariatric Surgery Candidate

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

group A

to know the effect of post-bariatric body contouring surgery on weight loss and metabolism

Group Type: EXPERIMENTAL

body contouring

Intervention Type: PROCEDURE

any post-bariatric body contouring surgery included

group B

compare this group of patients with group A to detect weight changes and metabolic changes without any post-bariatric intervention

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

body contouring

any post-bariatric body contouring surgery included

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Post-bariatric (sleeve) patients will do body contouring surgery.
• Post-bariatric patients has been stable within 5 kg for 3 months
• Age between 20-60 years old.
• patients use the determinant fixed diet.

Exclusion Criteria

• Age below 20 and above 60 years old.
• Non-compliance with the fixed diet.
• psychotic patients.
• Female patients seeking pregnancy.
• Endocrine causes of obesity.
• Bariatric surgery other than sleeve.

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Mohamed Shadad Rateb Mohamed

Assistant lecturer

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Mohamed Shadad, Master

Role: STUDY_DIRECTOR

Assiut University

Locations

Assiut University

Asyut, , Egypt

Countries

Egypt

Other Identifiers

AUN

Identifier Type: -

Identifier Source: org_study_id