Manual Chest Physiotherapy and Active Cycle of Breathing Techniques (ACBT) in Patients of Cystic Fibrosis

NCT ID: NCT05026918

Last Updated: 2021-08-30

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 14 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2020-10-13
• Study Completion Date: 2021-07-20

Brief Summary

Cystic fibrosis is a genetic disease (autosomal recessive) which involves malfunction of the exocrine glands, leading to abnormal secretions in the body. It is a progressive disease that causes persistent lung infections and limits the ability to breathe over time. Clinical symptoms include persistent coughing, at times with phlegm, wheezing or shortness of breath, fatigue, difficulty with bowel movements sinus infections, poor growth, clubbing of the fingers and toes, and infertility in most males. The disease must be managed throughout life with diet, medication and preventive chest physical therapy as soon as any symptoms are noted in the young child. The purpose of the study was to evaluate the difference between the effects of Manual Chest Physiotherapy (CPT) and Active Cycle of Breathing Techniques (ACBT) in patients of Cystic Fibrosis. The tools of our study were Modified Borg Dyspnea Scale and Quality of well-being Scale. The total sample of our study was 14 out of which 7 were included in GROUP A and 7 Group B. SPSS 23 was used for statistical analysis and parametric tests were used for analysis

Conditions

Cystic Fibrosis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Group A

all the components of Manual Chest Physiotherapy wer performed on the patients of this group. MCPT was done few hours before meals and it was made sure that nothing was in patient's mouth while doing chest physiotherapy. MCPT includes postural drainage, percussion and vibrations. Chest Physiotherapy was done thrice a day for 30 minutes and there were 21 sessions a week.

Group Type: ACTIVE_COMPARATOR

MCPT

Intervention Type: OTHER

Postural Drainagewith percussion and vibration

Group B

all the components of Active Cycle of Breathing techniques (ACBT) were performed on the patients of this group. ACBT includes Breathing control techniques, chest expansion exercises and Forced Expiration Technique. These were performed thrice a day for 30 minutes and for 21 sessions a week.

Group Type: EXPERIMENTAL

ACBT

Intervention Type: OTHER

ACBT includes Breathing control techniques, chest expansion exercises and Forced Expiration Technique

Interventions

MCPT

Postural Drainagewith percussion and vibration

Intervention Type: OTHER

ACBT

ACBT includes Breathing control techniques, chest expansion exercises and Forced Expiration Technique

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age limit 5-25
• Patients with confirmed diagnosis of Cystic Fibrosis
• Male and female.
• Clinically Stable Patients

Exclusion Criteria

• Hypertensive patients.
• Intolerant patients.
• Compromised Renal Function.
• Other Comorbidities

• Minimum Eligible Age: 5 Years
• Maximum Eligible Age: 25 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Riphah International University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Fareeha Kausar, MSCPPT

Role: PRINCIPAL_INVESTIGATOR

Riphah International University

Locations

PAF Hospital

Islamabad, Capital, Pakistan

Countries

Pakistan

References

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Reference Type: BACKGROUND

PMID: 33792230 (View on PubMed)

van der Schans C, Prasad A, Main E. Chest physiotherapy compared to no chest physiotherapy for cystic fibrosis. Cochrane Database Syst Rev. 2000;(2):CD001401. doi: 10.1002/14651858.CD001401.

Reference Type: BACKGROUND

PMID: 10796781 (View on PubMed)

Reisman JJ, Rivington-Law B, Corey M, Marcotte J, Wannamaker E, Harcourt D, Levison H. Role of conventional physiotherapy in cystic fibrosis. J Pediatr. 1988 Oct;113(4):632-6. doi: 10.1016/s0022-3476(88)80370-6.

Reference Type: BACKGROUND

PMID: 3171787 (View on PubMed)

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Reference Type: BACKGROUND

PMID: 27086904 (View on PubMed)

McIlwaine MP, Lee Son NM, Richmond ML. Physiotherapy and cystic fibrosis: what is the evidence base? Curr Opin Pulm Med. 2014 Nov;20(6):613-7. doi: 10.1097/MCP.0000000000000110.

Reference Type: BACKGROUND

PMID: 25225791 (View on PubMed)

Bradley JM, Moran FM, Elborn JS. Evidence for physical therapies (airway clearance and physical training) in cystic fibrosis: an overview of five Cochrane systematic reviews. Respir Med. 2006 Feb;100(2):191-201. doi: 10.1016/j.rmed.2005.11.028.

Reference Type: BACKGROUND

PMID: 16412951 (View on PubMed)

Williams MT, Parsons DW, Frick RA, Ellis ER, Martin AJ, Giles SE, Grant ER. Acute respiratory infection in patients with cystic fibrosis with mild pulmonary impairment: comparison of two physiotherapy regimens. Aust J Physiother. 2001;47(4):227-36. doi: 10.1016/s0004-9514(14)60270-1.

Reference Type: BACKGROUND

PMID: 11722291 (View on PubMed)

Williams MT. Chest physiotherapy and cystic fibrosis. Why is the most effective form of treatment still unclear? Chest. 1994 Dec;106(6):1872-82. doi: 10.1378/chest.106.6.1872. No abstract available.

Reference Type: BACKGROUND

PMID: 7988215 (View on PubMed)

Other Identifiers

REC/Lhr/0332 Hafsa Javed

Identifier Type: -

Identifier Source: org_study_id