Essential Oil for Chronic Low Back Pain

NCT ID: NCT05021146

Last Updated: 2021-10-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-09-01

Study Completion Date

2023-03-31

Brief Summary

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The specific objective of this study is to assess the safety and clinical efficacy of a new individualised spinal rehabilitation programme involving copaiba essential oil (CEO) therapy compared to usual care for people with chronic low back pain. Research in complementary and alternative medicine has increased over the last 15 years. As biochemical research shows, these substances carry the ability to relieve pain and to reduce inflammation. In doing so, it aims to:

1. Improve the health outcomes for individuals with chronic low back pain (CLBP) by positively impacting their pain, disability, work capacity, physical activity and mental health, and
2. Reduce the chronic health burden on society associated with treatment, sick leave, rehabilitation, and involuntary retirement, by reducing health-related costs.

The primary clinical hypothesis is that patients with CLBP receiving individualised spinal care and additional CEO topical treatment will have superior short- and long-term outcome (defined by condition specific quality of life and general well-being) compared to usual care.

Detailed Description

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Conditions

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Chronic Low-back Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Standard care and CEO treatment with standard 20% concentration Copaiba oil

Group Type EXPERIMENTAL

usual care and topical essential copaiba oil

Intervention Type OTHER

All subjects will receive daily interdisciplinary - multimodular -treatment during their hospital stay including a daily 30 minute massage therapy. Both experimental groups and the placebo group patients continue to use topical treatment in the first half of the follow up period (90 days).

Standard care and CEO treatment with 40% concentration Copaiba oil

Group Type EXPERIMENTAL

usual care and topical essential copaiba oil

Intervention Type OTHER

All subjects will receive daily interdisciplinary - multimodular -treatment during their hospital stay including a daily 30 minute massage therapy. Both experimental groups and the placebo group patients continue to use topical treatment in the first half of the follow up period (90 days).

standard care and placebo treatment with coconut oil

Group Type PLACEBO_COMPARATOR

usual care and placebo treatment

Intervention Type OTHER

All subjects will receive daily interdisciplinary - multimodular -treatment during their hospital stay including a daily 30 minute massage therapy. Both experimental groups and the placebo group patients continue to use topical treatment in the first half of the follow up period (90 days).

Standard care

Group Type ACTIVE_COMPARATOR

usual care

Intervention Type OTHER

All subjects will receive daily interdisciplinary - multimodular -treatment during their hospital stay.

Interventions

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usual care and topical essential copaiba oil

All subjects will receive daily interdisciplinary - multimodular -treatment during their hospital stay including a daily 30 minute massage therapy. Both experimental groups and the placebo group patients continue to use topical treatment in the first half of the follow up period (90 days).

Intervention Type OTHER

usual care and placebo treatment

All subjects will receive daily interdisciplinary - multimodular -treatment during their hospital stay including a daily 30 minute massage therapy. Both experimental groups and the placebo group patients continue to use topical treatment in the first half of the follow up period (90 days).

Intervention Type OTHER

usual care

All subjects will receive daily interdisciplinary - multimodular -treatment during their hospital stay.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Chronic low back pain with or without irradiating pain (pain \> 3 months)
* Low back pain is the dominant symptom, and Visual Analog Pain Scale (low back pain)\>4
* Normal cognitive function, voluntary participation
* Able to read and answer the questionnaires in English or Hungarian language

Exclusion Criteria

* Previous spinal surgery
* Untreated metabolic bone disease
* Active malignant disease
* Pregnancy
* Severe osteoporosis, fracture or posttraumatic deformity
* Spinal infection
* Neuromuscular disease
* Autoimmune disease
* Myelopathy
* Congenital spinal deformity
* Mental disorders
* Severe sciatica
* Severe spinal instability
* Refusing the study protocol
Minimum Eligible Age

40 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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dōTERRA International

INDUSTRY

Sponsor Role collaborator

Buda Health Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Peter Pal Varga, MD

Role: PRINCIPAL_INVESTIGATOR

Buda Health Center

Locations

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National Center for Spinal Disorders / Buda Health Center

Budapest, , Hungary

Site Status RECRUITING

Countries

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Hungary

Central Contacts

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Aron Lazary, PhD

Role: CONTACT

+3618877900

Julia Szita, PhD

Role: CONTACT

+3618877900 ext. 5670

Facility Contacts

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Aron Lazary, PhD

Role: primary

+3618877900

Julia Szita, PhD

Role: backup

+3618877900

Other Identifiers

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DO-221014-COP

Identifier Type: -

Identifier Source: org_study_id