Oral Herbal Combination Formulation and Hair Growth in Women

NCT ID: NCT05019066

Last Updated: 2021-10-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2021-09-30

Study Completion Date

2022-06-01

Brief Summary

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The purpose of this research is to test the effects of an herbal combination formulation on hair growth in women with self-perceived hair loss.The information from this study may help to better understand how certain herbal supplements can affect hair growth. This may lead to better understanding of the hair, hair loss and help develop naturally-based treatment regimens in the future.

Detailed Description

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Conditions

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Hair Loss Hair Thinning

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Herbal Combination Group

* Tablets of the herbal formulation will be supplied from Banyan Botanicals (https://www.banyanbotanicals.com/healthy-hair-tablets-10)
* Each 500 mg tablet contains a proprietary blend of: Eclipta alba, Emblica officinalis, Centella asiatica and Hibiscus sabdariffa
* Dose: subjects in this group will take 2 herbal formulation tablets twice per day for a total of 4 tablets per day

Group Type ACTIVE_COMPARATOR

Herbal Supplementation

Intervention Type DIETARY_SUPPLEMENT

A proprietary blend of: Eclipta alba, Emblica officinalis, Centella asiatica and Hibiscus sabdariffa.

Placebo Group

* Supplement appearing similar to the herbal combination formulation.
* Each placebo tablet will contain microcrystalline cellulose, dicalcium phosphate, PVPK30, sodium starch glycolate, magnesium stearate, OpaDry orange coating.
* Dose: subjects in this group will take 2 placebo tablets twice per day for a total of 4 tablets per day

Group Type PLACEBO_COMPARATOR

Herbal Supplementation

Intervention Type DIETARY_SUPPLEMENT

A proprietary blend of: Eclipta alba, Emblica officinalis, Centella asiatica and Hibiscus sabdariffa.

Interventions

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Herbal Supplementation

A proprietary blend of: Eclipta alba, Emblica officinalis, Centella asiatica and Hibiscus sabdariffa.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Age 18 and above
* Subject must be able to read and comprehend study procedures and consent forms.
* Women with self-perceived hair loss as confirmed by the investigator.
* Willing to maintain the same hairstyle, hair color, hair length and hair regimen throughout the study period. Subjects with color-treated hair will have the color treatment performed at the same time interval prior to each visit (if the color treatment was done 1 week prior to Visit 1, it should be repeated 1 week prior to Visit 2).
* Willing to keep diet and exercise routine consistent throughout study

Exclusion Criteria

* Subjects should be generally healthy and have no smoking history in the past one year.
* Subjects must have no history of diabetes, metabolic syndrome, HIV, immune deficiency, autoimmune disease known cardiovascular disease, malignancy, kidney disease, or chronic steroid use.
* Women who are pregnant, planning to become pregnant or breastfeeding
* Those who are unable to discontinue medicated shampoos or topical scalp medications for two weeks prior to and during the study.
* Those who are unable to discontinue supplements containing Eclipta alba, Emblica officinalis, Centella asiatica and Hibiscus sabdariffa for one month prior to starting the study
* Those who have a known allergy to Eclipta alba, Emblica officinalis, Centella asiatica or Hibiscus sabdariffa
* Use of hair regrowth products in the previous 6 months
* Using or planned use of non-breathable wigs
* Those with a history of hair transplantation procedure
* Presence of other dermatological disorders causing alopecia
* Chemotherapy, radiation therapy or laser therapy (of scalp) in the last 6 months
* Light therapy in the past 3 months
* Participants using hormonal birth control unless on a stable / unchanged regimen for at least 3 months.
* Systemic treatment during the last 3 months before study inclusion that could interfere with the study medications (ie, minoxidil, corticosteroids, Aminexil, topical estrogens, ketoconazole, beta blocker, cimetidine, diazoxide, isotretinoin or vitamin A intake \>10,000 IU/d)
* Use of ocular prostaglandins for less than 4 months before first study visit
* Those that are prisoners or cognitively impaired
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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University of California, Davis

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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1396273

Identifier Type: -

Identifier Source: org_study_id