Study for the Quantification in Ecological Conditions of Sensorimotor and Dysexecutive Disorders in Cerebral Palsy Patients

NCT ID: NCT05017051

Last Updated: 2022-12-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

442 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-13

Study Completion Date

2028-10-31

Brief Summary

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Executive functions are defined as the mental functions necessary for an individual to adapt to a complex or new environment that requires freedom from automatic and routine behavior. Deficits in executive functions are described under the term "dysexecutive syndrome", and call into question the quality of social and professional life as well as the autonomy of patients.

The usual methods of identifying dysexecutive syndrome are based essentially on batteries of neuropsychological tests known as "paper and pencil". However, these tests may lack sensitivity, in that they assess the patient in a very structured setting, very different from real life conditions, which are full of distractions and choices to be made.

Evaluations on real tasks are more rarely used but have the advantage of observing the difficulties encountered by a patient in everyday life.

Two tests of this type have been set up in the Neurology Department of the Hôpital d'Instruction des Armées Percy, and are integrated into the routine care of patients with a dysexecutive syndrome.

For this purpose, a room in the department has been set up as a studio in order to reproduce as much as possible an everyday life environment, in which executive functions, fine motor skills, neurovegetative functions, emotional state, posture, locomotor skills and visual information capture can be measured ecologically.

Detailed Description

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Conditions

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Dysexecutive Syndrome

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Dysexecutive patients

Patients with dysexecutive syndrome

Chocolate cake

Intervention Type BEHAVIORAL

The participants will have to make a chocolate cake following an imposed recipe at 4 visits (initially (M0), after 12 months (M12), after 24 months (M24) and after 36 months (M36)).

Lego model

Intervention Type BEHAVIORAL

The participants will have to build a Lego model at 4 visits (M0, M12, M24 and M36).

Measurement of sensorimotor abilities

Intervention Type DEVICE

The measurement of sensorimotor abilities is based on a multi-sensor device called Smart Flat specifically designed for this study at 4 visits (M0, M12, M24 and M36).

Measurement of facial expression of emotions

Intervention Type OTHER

Participants will have to evoke an emotionally charged autobiographical story by modulating facial expressions through a mirror at 4 visits (M0, M12, M24 and M36).

Healthy subjects

Healthy subjects to be used as control group

Chocolate cake

Intervention Type BEHAVIORAL

The participants will have to make a chocolate cake following an imposed recipe at 4 visits (initially (M0), after 12 months (M12), after 24 months (M24) and after 36 months (M36)).

Lego model

Intervention Type BEHAVIORAL

The participants will have to build a Lego model at 4 visits (M0, M12, M24 and M36).

Measurement of sensorimotor abilities

Intervention Type DEVICE

The measurement of sensorimotor abilities is based on a multi-sensor device called Smart Flat specifically designed for this study at 4 visits (M0, M12, M24 and M36).

Measurement of facial expression of emotions

Intervention Type OTHER

Participants will have to evoke an emotionally charged autobiographical story by modulating facial expressions through a mirror at 4 visits (M0, M12, M24 and M36).

Interventions

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Chocolate cake

The participants will have to make a chocolate cake following an imposed recipe at 4 visits (initially (M0), after 12 months (M12), after 24 months (M24) and after 36 months (M36)).

Intervention Type BEHAVIORAL

Lego model

The participants will have to build a Lego model at 4 visits (M0, M12, M24 and M36).

Intervention Type BEHAVIORAL

Measurement of sensorimotor abilities

The measurement of sensorimotor abilities is based on a multi-sensor device called Smart Flat specifically designed for this study at 4 visits (M0, M12, M24 and M36).

Intervention Type DEVICE

Measurement of facial expression of emotions

Participants will have to evoke an emotionally charged autobiographical story by modulating facial expressions through a mirror at 4 visits (M0, M12, M24 and M36).

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with a dysexecutive syndrome OR healthy subjects
* Over 18 years-old

Exclusion Criteria

* Patients

* Psychiatric pathology (except for Post-Traumatic Stress Disorder)
* Pregnant or breastfeeding woman
* Healthy subjects

* Neurologic or psychiatric pathology
* Pregnant or breastfeeding woman
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Direction Centrale du Service de Santé des Armées

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hôpital d'Instruction des Armées Percy

Clamart, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Flavie BOMPAIRE, MD

Role: CONTACT

Phone: 141466877

Email: [email protected]

Facility Contacts

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Flavie BOMPAIRE, MD

Role: primary

Other Identifiers

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2021-A00087-34

Identifier Type: OTHER

Identifier Source: secondary_id

2018PPRC34

Identifier Type: -

Identifier Source: org_study_id