Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE4
732 participants
INTERVENTIONAL
2021-08-20
2022-12-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
TREATMENT
NONE
Study Groups
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RA group
Rabeprazole
20mg bid
Amoxicillin
1g tid
RAM group
Rabeprazole
20mg bid
Metronidazole
0.4g tid
Amoxicillin
1g tid
RAB group
Rabeprazole
20mg bid
Bismuth potassium citrate
0.6g bid
Amoxicillin
1g tid
RABM group
Rabeprazole
20mg bid
Bismuth potassium citrate
0.6g bid
Metronidazole
0.4g tid
Amoxicillin
1g tid
Interventions
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Rabeprazole
20mg bid
Bismuth potassium citrate
0.6g bid
Metronidazole
0.4g tid
Amoxicillin
1g tid
Eligibility Criteria
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Inclusion Criteria
* 18-75 years old on the day of signing the ICF.
* Helicobacter pylori infection confirmed by 13C-urea breath test or rapid urease test.
* Have not received Helicobacter pylori eradication treatment before.
Exclusion Criteria
* Patients with severe heart, lung, kidney, liver, blood, nerve, endocrine, and psychiatric diseases.
* Subjects or guardians refused to participate in the trial.
* Alcohol and/or drugs Abuse (addiction or dependence) or poor compliance with doctor's judgment.
* Have taken antibiotics, bismuth, PPI or Chinese traditional medicine 4 weeks before treatment.
* Pregnant or lactating women.
* Active peptic ulcer.
* allergic to drugs used in the trial.
* any other circumstances that are not suitable for recruitment.
18 Years
75 Years
ALL
No
Sponsors
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Shanghai Zhongshan Hospital
OTHER
Responsible Party
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Principal Investigators
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Taotao Liu, MD
Role: PRINCIPAL_INVESTIGATOR
Fudan University
Locations
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Zhongshan Hospital, Fudan University
Shanghai, Shanghai Municipality, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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B2021-3761
Identifier Type: -
Identifier Source: org_study_id
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