Current Treatment Outcomes in Japanese RCC Patients Treated With Avelumab Plus Axitinib as First-line Therapy: Retrospective Study (J-DART)

NCT ID: NCT05012865

Last Updated: 2023-12-06

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

48 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-14

Study Completion Date

2022-01-31

Brief Summary

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This study is a multicenter, non-interventional, retrospective, medical chart review of patients with metastatic renal cell cancer(mRCC) treated with avelumab plus axitinib as a first-line therapy in Japan between 20 December 2019 and 20 December 2020. All decisions regarding clinical management and treatment of the participating patients were made by the investigator as part of standard care in real-world clinical setting and were not contingent upon the patient's participation in the study. Data will be collected if available per study site.

Detailed Description

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Conditions

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Renal Cell Carcinoma

Keywords

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Retrospective Multicenter Non-interventional Medical chart review Japan Metastatic renal cell cancer(mRCC) Avelumab Axitinib First-line therapy Standard care in real-world clinical setting

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients with metastatic renal cell carcinoma

Patients with metastatic renal cell carcinoma

avelumab

Intervention Type DRUG

as provided in real world practice

axitinib

Intervention Type DRUG

as provided in real world practice

Interventions

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avelumab

as provided in real world practice

Intervention Type DRUG

axitinib

as provided in real world practice

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Diagnosed with metastatic renal cell cancer(mRCC) based on the General Rule for Clinical and Pathological Studies on Renal Cell Carcinoma (4th Edition) before receiving avelumab plus axitinib as a first-line therapy.
2. Over 20 years of age at the time of metastatic renal cell cancer(mRCC) diagnosis.
3. Start treatment with avelumab plus axitinib as a first-line therapy for metastatic renal cell cancer(mRCC) from 20 December 2019 to 20 December 2020.
4. For patients who are still alive and have routine visits to the study site, evidence of a personally signed and dated informed consent document indicating that the patient has been informed of all pertinent aspects of the study. For patients who are still alive and had been transferred to another hospital, evidence that the patient has been informed of all pertinent aspects of the study and oral or written informed consent is obtained.
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pfizer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pfizer CT.gov Call Center

Role: STUDY_DIRECTOR

Pfizer

Locations

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Kurume University Hospital

Kurume, Fukuoka, Japan

Site Status

Gunma Prefectural Cancer Center

Ōta, Gunma, Japan

Site Status

Asahikawa Medical University Hospital

Asahikawa, Hokkaido, Japan

Site Status

Iwamizawa Municipal General Hospital

Iwamizawa, Hokkaido, Japan

Site Status

Kobe University Hospital

Kobe, Hyōgo, Japan

Site Status

University Hospital,Kyoto Prefectural University of Medicine

Kamigyō-ku, Kyoto, Japan

Site Status

Kindai University Hospital

Sayama, Osaka, Japan

Site Status

Osaka University Hospital

Suita, Osaka, Japan

Site Status

Osaka Medical and Pharmaceutical University Hospital

Takatsuki, Osaka, Japan

Site Status

Jichi Medical University Saitama Medical Center

Saitama, Saitama, Japan

Site Status

Hiroshima University Hospital

Hiroshima, , Japan

Site Status

Osaka City University Hospital

Osaka, , Japan

Site Status

Countries

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Japan

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Related Links

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https://pmiform.com/clinical-trial-info-request?StudyID=B9991043

To obtain contact information for a study center near you, click here.

Other Identifiers

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B9991043

Identifier Type: -

Identifier Source: org_study_id