Trial Outcomes & Findings for Lottery Incentive Nudges to Increase Influenza Vaccinations (NCT NCT05012163)

NCT ID: NCT05012163

Last Updated: 2024-12-30

Results Overview

Received flu vaccination at relevant PCP or specialty appointment.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

57581 participants

Primary outcome timeframe

3 days after patient is randomized

Results posted on

2024-12-30

Participant Flow

Participant milestones

Participant milestones
Measure
Pennsylvania (PA) Lottery Scratch-Off Financial Incentive
Participants in this arm will receive a message stating that they will receive a PA lottery $1 scratch-off ticket if they get a flu shot at an upcoming appointment. The message will mention that they could win $5,000 (the top prize for the scratch-off game). Note: $1 scratch-off products vary over time; at study implementation, an active game with top prize of $5,000 (or the next-highest top prize) will be selected and will define the prize in the raffle absent upfront odds Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email Lottery: Letter, SMS, phone, and/or email
Certain Cash Payout Financial Incentive
Participants in this arm will receive a message stating that they will receive $1 in cash if they get a flu shot at an upcoming appointment. Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email
Reminder / Active Control (No Financial Incentive)
Participants in this arm will receive a message stating that they can get a flu shot at an upcoming appointment. These participants will not be offered a financial incentive for getting a flu shot. Reminder: Letter, short message service (SMS) text, phone, and/or email
No Treatment Control
No additional contact beyond standard Geisinger flu shot communications
Overall Study
STARTED
14394
14394
14394
14399
Overall Study
COMPLETED
14394
14394
14393
14398
Overall Study
NOT COMPLETED
0
0
1
1

Reasons for withdrawal

Reasons for withdrawal
Measure
Pennsylvania (PA) Lottery Scratch-Off Financial Incentive
Participants in this arm will receive a message stating that they will receive a PA lottery $1 scratch-off ticket if they get a flu shot at an upcoming appointment. The message will mention that they could win $5,000 (the top prize for the scratch-off game). Note: $1 scratch-off products vary over time; at study implementation, an active game with top prize of $5,000 (or the next-highest top prize) will be selected and will define the prize in the raffle absent upfront odds Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email Lottery: Letter, SMS, phone, and/or email
Certain Cash Payout Financial Incentive
Participants in this arm will receive a message stating that they will receive $1 in cash if they get a flu shot at an upcoming appointment. Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email
Reminder / Active Control (No Financial Incentive)
Participants in this arm will receive a message stating that they can get a flu shot at an upcoming appointment. These participants will not be offered a financial incentive for getting a flu shot. Reminder: Letter, short message service (SMS) text, phone, and/or email
No Treatment Control
No additional contact beyond standard Geisinger flu shot communications
Overall Study
Protocol Violation
0
0
1
1

Baseline Characteristics

Lottery Incentive Nudges to Increase Influenza Vaccinations

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Pennsylvania (PA) Lottery Scratch-Off Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive a PA lottery $1 scratch-off ticket if they get a flu shot at an upcoming appointment. The message will mention that they could win $5,000 (the top prize for the scratch-off game). Note: $1 scratch-off products vary over time; at study implementation, an active game with top prize of $5,000 (or the next-highest top prize) will be selected and will define the prize in the raffle absent upfront odds Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email Lottery: Letter, SMS, phone, and/or email
Certain Cash Payout Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive $1 in cash if they get a flu shot at an upcoming appointment. Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email
Reminder / Active Control (No Financial Incentive)
n=14394 Participants
Participants in this arm will receive a message stating that they can get a flu shot at an upcoming appointment. These participants will not be offered a financial incentive for getting a flu shot. Reminder: Letter, short message service (SMS) text, phone, and/or email
No Treatment Control
n=14399 Participants
No additional contact beyond standard Geisinger flu shot communications
Total
n=57581 Participants
Total of all reporting groups
Age, Customized
<18
0 Participants
n=5 Participants
0 Participants
n=7 Participants
1 Participants
n=5 Participants
1 Participants
n=4 Participants
2 Participants
n=21 Participants
Age, Customized
18-65
11051 Participants
n=5 Participants
11105 Participants
n=7 Participants
11097 Participants
n=5 Participants
11066 Participants
n=4 Participants
44319 Participants
n=21 Participants
Age, Customized
65+
3343 Participants
n=5 Participants
3289 Participants
n=7 Participants
3296 Participants
n=5 Participants
3332 Participants
n=4 Participants
13260 Participants
n=21 Participants
Sex: Female, Male
Female
8370 Participants
n=5 Participants
8306 Participants
n=7 Participants
8313 Participants
n=5 Participants
8344 Participants
n=4 Participants
33333 Participants
n=21 Participants
Sex: Female, Male
Male
6024 Participants
n=5 Participants
6088 Participants
n=7 Participants
6081 Participants
n=5 Participants
6055 Participants
n=4 Participants
24248 Participants
n=21 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
643 Participants
n=5 Participants
659 Participants
n=7 Participants
701 Participants
n=5 Participants
661 Participants
n=4 Participants
2664 Participants
n=21 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
13670 Participants
n=5 Participants
13649 Participants
n=7 Participants
13624 Participants
n=5 Participants
13656 Participants
n=4 Participants
54599 Participants
n=21 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
81 Participants
n=5 Participants
86 Participants
n=7 Participants
69 Participants
n=5 Participants
82 Participants
n=4 Participants
318 Participants
n=21 Participants
Race/Ethnicity, Customized
American Indian or Alaska Native
42 Participants
n=5 Participants
29 Participants
n=7 Participants
30 Participants
n=5 Participants
29 Participants
n=4 Participants
130 Participants
n=21 Participants
Race/Ethnicity, Customized
Asian
135 Participants
n=5 Participants
112 Participants
n=7 Participants
130 Participants
n=5 Participants
148 Participants
n=4 Participants
525 Participants
n=21 Participants
Race/Ethnicity, Customized
Black or African American
595 Participants
n=5 Participants
609 Participants
n=7 Participants
615 Participants
n=5 Participants
595 Participants
n=4 Participants
2414 Participants
n=21 Participants
Race/Ethnicity, Customized
Native Hawaiian or Other Pacific Islander
50 Participants
n=5 Participants
51 Participants
n=7 Participants
56 Participants
n=5 Participants
53 Participants
n=4 Participants
210 Participants
n=21 Participants
Race/Ethnicity, Customized
White
13459 Participants
n=5 Participants
13484 Participants
n=7 Participants
13448 Participants
n=5 Participants
13457 Participants
n=4 Participants
53848 Participants
n=21 Participants
Race/Ethnicity, Customized
Unknown
113 Participants
n=5 Participants
109 Participants
n=7 Participants
115 Participants
n=5 Participants
117 Participants
n=4 Participants
454 Participants
n=21 Participants

PRIMARY outcome

Timeframe: 3 days after patient is randomized

Population: All enrolled patients were included in analyses, except the two patients who were inadvertently enrolled at age 17.

Received flu vaccination at relevant PCP or specialty appointment.

Outcome measures

Outcome measures
Measure
Pennsylvania (PA) Lottery Scratch-Off Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive a PA lottery $1 scratch-off ticket if they get a flu shot at an upcoming appointment. The message will mention that they could win $5,000 (the top prize for the scratch-off game). Note: $1 scratch-off products vary over time; at study implementation, an active game with top prize of $5,000 (or the next-highest top prize) will be selected and will define the prize in the raffle absent upfront odds Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email Lottery: Letter, SMS, phone, and/or email
Certain Cash Payout Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive $1 in cash if they get a flu shot at an upcoming appointment. Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email
Reminder / Active Control (No Financial Incentive)
n=14393 Participants
Participants in this arm will receive a message stating that they can get a flu shot at an upcoming appointment. These participants will not be offered a financial incentive for getting a flu shot. Reminder: Letter, short message service (SMS) text, phone, and/or email
No Treatment Control
n=14398 Participants
No additional contact beyond standard Geisinger flu shot communications
Flu Vaccination at Appointment
No Shot at Appointment
10461 Participants
10511 Participants
10394 Participants
10746 Participants
Flu Vaccination at Appointment
Shot at Appointment
3933 Participants
3883 Participants
3999 Participants
3652 Participants

SECONDARY outcome

Timeframe: Within 7 days of when patient is randomized

Received flu vaccination

Outcome measures

Outcome measures
Measure
Pennsylvania (PA) Lottery Scratch-Off Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive a PA lottery $1 scratch-off ticket if they get a flu shot at an upcoming appointment. The message will mention that they could win $5,000 (the top prize for the scratch-off game). Note: $1 scratch-off products vary over time; at study implementation, an active game with top prize of $5,000 (or the next-highest top prize) will be selected and will define the prize in the raffle absent upfront odds Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email Lottery: Letter, SMS, phone, and/or email
Certain Cash Payout Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive $1 in cash if they get a flu shot at an upcoming appointment. Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email
Reminder / Active Control (No Financial Incentive)
n=14393 Participants
Participants in this arm will receive a message stating that they can get a flu shot at an upcoming appointment. These participants will not be offered a financial incentive for getting a flu shot. Reminder: Letter, short message service (SMS) text, phone, and/or email
No Treatment Control
n=14398 Participants
No additional contact beyond standard Geisinger flu shot communications
Flu Vaccination Within 7 Days
No Shot Within 7 Days
10119 Participants
10104 Participants
10007 Participants
10343 Participants
Flu Vaccination Within 7 Days
Shot Within 7 Days
4275 Participants
4290 Participants
4386 Participants
4055 Participants

SECONDARY outcome

Timeframe: During the 2021-22 flu season (Up to 8 months, from the time the patient is randomized through April 30, 2022)

Received a "high confidence flu" diagnosis (with positive polymerase chain reaction \[PCR\]/antigen/molecular test) and/or "likely flu" diagnosis (as assessed via International Classification of Disease \[ICD\] codes or Tamiflu administration or positive PCR/antigen/molecular test) Note that "likely flu" is a superset of the "high confidence flu" diagnoses.

Outcome measures

Outcome measures
Measure
Pennsylvania (PA) Lottery Scratch-Off Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive a PA lottery $1 scratch-off ticket if they get a flu shot at an upcoming appointment. The message will mention that they could win $5,000 (the top prize for the scratch-off game). Note: $1 scratch-off products vary over time; at study implementation, an active game with top prize of $5,000 (or the next-highest top prize) will be selected and will define the prize in the raffle absent upfront odds Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email Lottery: Letter, SMS, phone, and/or email
Certain Cash Payout Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive $1 in cash if they get a flu shot at an upcoming appointment. Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email
Reminder / Active Control (No Financial Incentive)
n=14393 Participants
Participants in this arm will receive a message stating that they can get a flu shot at an upcoming appointment. These participants will not be offered a financial incentive for getting a flu shot. Reminder: Letter, short message service (SMS) text, phone, and/or email
No Treatment Control
n=14398 Participants
No additional contact beyond standard Geisinger flu shot communications
Flu Diagnosis
No flu diagnosis
14277 Participants
14262 Participants
14298 Participants
14265 Participants
Flu Diagnosis
Flu diagnosis
117 Participants
132 Participants
95 Participants
133 Participants

SECONDARY outcome

Timeframe: During the 2021-22 flu season (Up to 11 months, from the time the patient is randomized through July 31, 2022)

Diagnosed with flu-related complications

Outcome measures

Outcome measures
Measure
Pennsylvania (PA) Lottery Scratch-Off Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive a PA lottery $1 scratch-off ticket if they get a flu shot at an upcoming appointment. The message will mention that they could win $5,000 (the top prize for the scratch-off game). Note: $1 scratch-off products vary over time; at study implementation, an active game with top prize of $5,000 (or the next-highest top prize) will be selected and will define the prize in the raffle absent upfront odds Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email Lottery: Letter, SMS, phone, and/or email
Certain Cash Payout Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive $1 in cash if they get a flu shot at an upcoming appointment. Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email
Reminder / Active Control (No Financial Incentive)
n=14393 Participants
Participants in this arm will receive a message stating that they can get a flu shot at an upcoming appointment. These participants will not be offered a financial incentive for getting a flu shot. Reminder: Letter, short message service (SMS) text, phone, and/or email
No Treatment Control
n=14398 Participants
No additional contact beyond standard Geisinger flu shot communications
Flu Complications
No flu complications
12537 Participants
12613 Participants
12593 Participants
12605 Participants
Flu Complications
Flu complications
1857 Participants
1781 Participants
1800 Participants
1793 Participants

OTHER_PRE_SPECIFIED outcome

Timeframe: Within 28 days of when the study subject is randomized

Cohabitant of study subject received flu vaccination

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: 3 days after the patient is randomized.

Population: All enrolled patients were included in analyses, except the two patients who were inadvertently enrolled at age 17.

Received flu vaccination at relevant PCP or specialty appointment.

Outcome measures

Outcome measures
Measure
Pennsylvania (PA) Lottery Scratch-Off Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive a PA lottery $1 scratch-off ticket if they get a flu shot at an upcoming appointment. The message will mention that they could win $5,000 (the top prize for the scratch-off game). Note: $1 scratch-off products vary over time; at study implementation, an active game with top prize of $5,000 (or the next-highest top prize) will be selected and will define the prize in the raffle absent upfront odds Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email Lottery: Letter, SMS, phone, and/or email
Certain Cash Payout Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive $1 in cash if they get a flu shot at an upcoming appointment. Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email
Reminder / Active Control (No Financial Incentive)
n=14393 Participants
Participants in this arm will receive a message stating that they can get a flu shot at an upcoming appointment. These participants will not be offered a financial incentive for getting a flu shot. Reminder: Letter, short message service (SMS) text, phone, and/or email
No Treatment Control
n=14398 Participants
No additional contact beyond standard Geisinger flu shot communications
Flu Vaccination at Appointment by Gender
Female · No Shot at Appointment
6207 Participants
6132 Participants
6106 Participants
6290 Participants
Flu Vaccination at Appointment by Gender
Female · Shot at Appointment
2163 Participants
2174 Participants
2206 Participants
2054 Participants
Flu Vaccination at Appointment by Gender
Male · No Shot at Appointment
4254 Participants
4379 Participants
4288 Participants
4456 Participants
Flu Vaccination at Appointment by Gender
Male · Shot at Appointment
1770 Participants
1709 Participants
1793 Participants
1598 Participants

OTHER_PRE_SPECIFIED outcome

Timeframe: 3 days after the patient is randomized.

Population: All enrolled patients were included in analyses, except the two patients who were inadvertently enrolled at age 17.

Received flu vaccination at relevant PCP or specialty appointment.

Outcome measures

Outcome measures
Measure
Pennsylvania (PA) Lottery Scratch-Off Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive a PA lottery $1 scratch-off ticket if they get a flu shot at an upcoming appointment. The message will mention that they could win $5,000 (the top prize for the scratch-off game). Note: $1 scratch-off products vary over time; at study implementation, an active game with top prize of $5,000 (or the next-highest top prize) will be selected and will define the prize in the raffle absent upfront odds Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email Lottery: Letter, SMS, phone, and/or email
Certain Cash Payout Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive $1 in cash if they get a flu shot at an upcoming appointment. Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email
Reminder / Active Control (No Financial Incentive)
n=14393 Participants
Participants in this arm will receive a message stating that they can get a flu shot at an upcoming appointment. These participants will not be offered a financial incentive for getting a flu shot. Reminder: Letter, short message service (SMS) text, phone, and/or email
No Treatment Control
n=14398 Participants
No additional contact beyond standard Geisinger flu shot communications
Flu Vaccination at Appointment by Race
American Indian or Alaska Native · No Shot at Appointment
33 Participants
23 Participants
18 Participants
21 Participants
Flu Vaccination at Appointment by Race
American Indian or Alaska Native · Shot at Appointment
9 Participants
6 Participants
12 Participants
8 Participants
Flu Vaccination at Appointment by Race
Asian · No Shot at Appointment
92 Participants
78 Participants
89 Participants
101 Participants
Flu Vaccination at Appointment by Race
Black or African American · No Shot at Appointment
496 Participants
521 Participants
509 Participants
515 Participants
Flu Vaccination at Appointment by Race
Black or African American · Shot at Appointment
99 Participants
88 Participants
106 Participants
80 Participants
Flu Vaccination at Appointment by Race
Native Hawaiian or Other Pacific Islander · No Shot at Appointment
37 Participants
42 Participants
36 Participants
37 Participants
Flu Vaccination at Appointment by Race
Native Hawaiian or Other Pacific Islander · Shot at Appointment
13 Participants
9 Participants
20 Participants
16 Participants
Flu Vaccination at Appointment by Race
Unknown · No Shot at Appointment
85 Participants
90 Participants
93 Participants
96 Participants
Flu Vaccination at Appointment by Race
Unknown · Shot at Appointment
28 Participants
19 Participants
22 Participants
21 Participants
Flu Vaccination at Appointment by Race
White · No Shot at Appointment
9718 Participants
9757 Participants
9649 Participants
9976 Participants
Flu Vaccination at Appointment by Race
White · Shot at Appointment
3741 Participants
3727 Participants
3798 Participants
3480 Participants
Flu Vaccination at Appointment by Race
Asian · Shot at Appointment
43 Participants
34 Participants
41 Participants
47 Participants

OTHER_PRE_SPECIFIED outcome

Timeframe: 3 days after the patient is randomized.

Population: All enrolled patients were included in analyses, except the two patients who were inadvertently enrolled at age 17.

Received flu vaccination at relevant PCP or specialty appointment.

Outcome measures

Outcome measures
Measure
Pennsylvania (PA) Lottery Scratch-Off Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive a PA lottery $1 scratch-off ticket if they get a flu shot at an upcoming appointment. The message will mention that they could win $5,000 (the top prize for the scratch-off game). Note: $1 scratch-off products vary over time; at study implementation, an active game with top prize of $5,000 (or the next-highest top prize) will be selected and will define the prize in the raffle absent upfront odds Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email Lottery: Letter, SMS, phone, and/or email
Certain Cash Payout Financial Incentive
n=14394 Participants
Participants in this arm will receive a message stating that they will receive $1 in cash if they get a flu shot at an upcoming appointment. Reminder: Letter, short message service (SMS) text, phone, and/or email Financial incentive: Letter, SMS, phone, and/or email
Reminder / Active Control (No Financial Incentive)
n=14393 Participants
Participants in this arm will receive a message stating that they can get a flu shot at an upcoming appointment. These participants will not be offered a financial incentive for getting a flu shot. Reminder: Letter, short message service (SMS) text, phone, and/or email
No Treatment Control
n=14398 Participants
No additional contact beyond standard Geisinger flu shot communications
Flu Vaccination at Appointment by Ethnicity
Hispanic or Latino · No Shot at Appointment
511 Participants
517 Participants
525 Participants
530 Participants
Flu Vaccination at Appointment by Ethnicity
Hispanic or Latino · Shot at Appointment
132 Participants
142 Participants
175 Participants
130 Participants
Flu Vaccination at Appointment by Ethnicity
Not Hispanic or Latino · No Shot at Appointment
9889 Participants
9922 Participants
9812 Participants
10153 Participants
Flu Vaccination at Appointment by Ethnicity
Not Hispanic or Latino · Shot at Appointment
3781 Participants
3727 Participants
3812 Participants
3503 Participants
Flu Vaccination at Appointment by Ethnicity
Unknown · No Shot at Appointment
61 Participants
72 Participants
57 Participants
63 Participants
Flu Vaccination at Appointment by Ethnicity
Unknown · Shot at Appointment
20 Participants
14 Participants
12 Participants
19 Participants

Adverse Events

Pennsylvania (PA) Lottery Scratch-Off Financial Incentive

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Certain Cash Payout Financial Incentive

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Reminder / Active Control (No Financial Incentive)

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

No Treatment Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Gail Rosenbaum

Geisinger

Phone: 800-275-6401

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place