Quality of Life in Binge Eating Disorder.

NCT ID: NCT05010798

Last Updated: 2024-02-06

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 98 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2019-06-01
• Study Completion Date: 2023-10-01

Brief Summary

Binge Eating Disorder (BED) patients tend to report low quality of life (Qol). However, research is limited. Most research on Qol in BED include generic measures, rather than disease specific. Obesity is prevalent in BED, but contradicting evidence exists on the influence of obesity in BED.

Detailed Description

Eating disorders (ED's) are a group of disorders characterized by abnormal eating behaviors ranging from insufficient to excessive food intake, with concurrent disturbances in thoughts and emotions. Binge Eating Disorder (BED) is the most prevalent ED in both men and women, yet was only recently included in the Diagnostic and Statistical Manual of Mental Disorders fifth edition (DSM-5) as a diagnostic entity.

In general, ED's have been associated with significantly worse health related quality of life (HRQoL) compared to healthy population.

High rates of overweight (BMI ≥ 25) and obesity (BMI ≥ 30) are found in BED patients and obesity in itself is associated with lower QoL. The most widely used tools to measure Qol in ED's are the Medical Outcome Studies Short Form (SF) Scale, e.g. SF-36 and SF-12, which are generic in nature. Generic QoL measures have shown lack of sensitivity for some ED diagnoses and might not be suitable enough to pick up unique features that might characterize each disorder.

The objective of this study is to evaluate quality of life in Danish BED patients before treatment by using disease specific Qol measure. Furthermore, we want to assess the impact of obesity and depression on disease specific Qol in BED patients. The hypothesis are that obesity and depression will be associated with an impaired level of disease specific Qol.

Conditions

Binge-Eating Disorder; Quality of Life

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Eligibility Criteria

Inclusion Criteria

1. Patients referred to treatment for BED at Center f. Eating Disorders, OUH.

Exclusion Criteria

1. Extremely severe BED.

2. Severe psychiatric comorbidity.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of Southern Denmark

OTHER

Sponsor Role: collaborator

Region of Southern Denmark

OTHER

Sponsor Role: collaborator

Odense University Hospital

OTHER

Sponsor Role: lead

Responsible Party

René Klinkby Støving

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

René K Støving, PhD

Role: PRINCIPAL_INVESTIGATOR

Odense UH

Locations

Center for eating Disorders, Odense University Hospital

Odense, , Denmark

Department of Endocrinology, Odense University Hospital

Odense, , Denmark

Countries

Denmark

References

Winkler LA, Gudex C, Lichtenstein MB, Roder ME, Adair CE, Sjogren JM, Stoving RK. Explanatory Factors for Disease-Specific Health-Related Quality of Life in Women with Anorexia Nervosa. J Clin Med. 2021 Apr 9;10(8):1592. doi: 10.3390/jcm10081592.

Reference Type: BACKGROUND

PMID: 33918786 (View on PubMed)

Gudmundsdottir S, Linnet J, Lichtenstein MB, Adair CE, Carlsson SD, Brandt L, Rasmussen J, Stoving RK. Low quality of life in binge eating disorder compared to healthy controls. Dan Med J. 2023 Mar 14;70(4):A07220443.

Reference Type: DERIVED

PMID: 36999814 (View on PubMed)

Other Identifiers

QoL BED

Identifier Type: -

Identifier Source: org_study_id