TVMR With the Innovalve System Trial - Pilot Study in Italy

NCT ID: NCT05010746

Last Updated: 2025-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

4 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-24

Study Completion Date

2029-10-04

Brief Summary

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Study to evaluate the safety and performance of the Innovalve mitral valve replacement system

Detailed Description

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Conditions

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Mitral Valve Regurgitation (Degenerative or Functional)

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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MV replacement with Innovalve MR system

MV replacement with Innovalve MR system

Group Type EXPERIMENTAL

Innovalve TMVR system

Intervention Type DEVICE

Innovalve TMVR system

Interventions

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Innovalve TMVR system

Innovalve TMVR system

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Clinically significant, symptomatic mitral regurgitation
* High risk for open-heart surgery
* Meets anatomical criteria

Exclusion Criteria

* Unsuitable anatomy
* Patient is inoperable
* EF \<30%
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Edwards Lifesciences

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Antonio Colombo, Prof

Role: PRINCIPAL_INVESTIGATOR

Humanitas IRCCS

Locations

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Humanitas

Milan, , Italy

Site Status

Countries

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Italy

Other Identifiers

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INVL20-01-IT

Identifier Type: -

Identifier Source: org_study_id

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