A Study to Evaluate IBI112 in the Treatment of Subjects With Moderate to Severe Plaque Psoriasis
NCT ID: NCT05003531
Last Updated: 2024-01-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
250 participants
INTERVENTIONAL
2021-09-23
2023-01-17
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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IBI112 dose 1
Participants will receive IBI112 dose 1 subcutaneous injection(SC)
IBI112 dose 1
Participants will receive placebo or dose 1 IBI112 SC
IBI112 dose 4
Participants will receive IBI112 dose 4 subcutaneous injection(SC)
IBI112 dose 4
Participants will receive placebo or dose 4 IBI112 SC
IBI112 dose 2
Participants will receive IBI112 dose 2 subcutaneous injection(SC)
IBI112 dose 2
Participants will receive placebo or dose 2 IBI112 SC
IBI112 dose 3
Participants will receive IBI112 dose 3 subcutaneous injection(SC)
IBI112 dose 3
Participants will receive placebo or dose 3 IBI112 SC
Placebo
Participants will receive placebo subcutaneous injection(SC)
placebo
Participants will receive placebo SC
Interventions
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IBI112 dose 2
Participants will receive placebo or dose 2 IBI112 SC
IBI112 dose 4
Participants will receive placebo or dose 4 IBI112 SC
IBI112 dose 1
Participants will receive placebo or dose 1 IBI112 SC
IBI112 dose 3
Participants will receive placebo or dose 3 IBI112 SC
placebo
Participants will receive placebo SC
Eligibility Criteria
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Inclusion Criteria
* Must be a candidate for phototherapy or systemic treatment for psoriasis (either new to treatment or having had previous treatment)
Exclusion Criteria
* Participant has history of erythrodermic psoriasis, generalized or localized pustular psoriasis, medication-induced or medication-exacerbated psoriasis, or new onset guttate psoriasis
* Has received any therapeutic agent directly targeted to IL-12, IL-17, or IL-23within 6 months of the first administration of study agent
* Has received any therapeutic agent directly targeted toTNF-a within 3 months of the first administration of study agent
* Has received any conventional therapeutic agent within 1 months of the first administration of study agent
* Has received any topic therapeutic agent within 2 weeks of the first administration of study agent
18 Years
75 Years
ALL
No
Sponsors
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Innovent Biologics (Suzhou) Co. Ltd.
INDUSTRY
Responsible Party
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Locations
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PeKing University People's Hostpital
Beijing, Beijing Municipality, China
Countries
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Other Identifiers
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CIBI112A201
Identifier Type: -
Identifier Source: org_study_id
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