Quantification of Cannabinoids and Comparison to Post-Surgical Pain Medication Requirements and Surgical Outcomes

NCT ID: NCT04988490

Last Updated: 2025-03-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

68 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-11

Study Completion Date

2024-06-14

Brief Summary

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To determine how daily cannabis use affects surgical outcomes.

Detailed Description

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To determine if patients who are daily cannabis users that are undergoing inpatient abdominal surgery for the treatment of cancer are different from non-cannabis users regarding phytocannabinoid and endocannabinoid levels, pain scores, pain medication requirements, and surgical complications.

Conditions

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Post-Surgical Pain Post-Surgical Complication Cancer Cannabis Use

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Daily cannabis users

Patients undergoing inpatient abdominal surgery for the treatment of cancer who self-report daily cannabis use

No interventions assigned to this group

Cannabis non-users

Patients undergoing inpatient abdominal surgery for the treatment of cancer who self-report no cannabis use

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients \> 18 years old
* Undergoing abdominal surgery for the treatment of cancer
* Report no cannabis use in the last year or chronic cannabis use (defined as at least weekly use for 3 months or more)

Exclusion Criteria

* patients with chronic pain, chronic pain syndrome on opioids
* female patients who are pregnant or lactating
* patients who report use of illicit substances
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Institute of Cannabis Research

UNKNOWN

Sponsor Role collaborator

University of Colorado, Denver

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ana Gleisner

Role: PRINCIPAL_INVESTIGATOR

University of Colorado, Denver

Locations

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University of Colorado Hospital

Denver, Colorado, United States

Site Status

Countries

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United States

Other Identifiers

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P30CA046934

Identifier Type: NIH

Identifier Source: secondary_id

View Link

NCI-2021-08865

Identifier Type: OTHER

Identifier Source: secondary_id

21-3544.cc

Identifier Type: -

Identifier Source: org_study_id

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