The EU Hyprotect Registry

NCT ID: NCT04972266

Last Updated: 2024-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

702 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-28

Study Completion Date

2022-09-01

Brief Summary

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European, multicenter, prospective, observational registry in patients undergoing elective major non-cardiac surgery

Detailed Description

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Conditions

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Hemodynamic Monitoring

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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AcumenTM Hypotension Prediction Index software

The AcumenTM HPI Feature Software provides the clinician with physiological insight into a patient's likelihood of trending toward a hypotensive event. The AcumenTM HPI Feature Software suite is enabled by the minimally invasive Acumen IQ sensor.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Consenting adult patients (≥18 years)
* Patient is scheduled for elective major non-cardiac surgery under general anesthesia that is expected to last at least 120 minutes and in whom blood pressure is monitored using an arterial catheter
* Patients in whom the AcumenTM Hypotension Prediction Index software with the Acumen IQ sensor on the Hemosphere platform is used intraoperatively

Exclusion Criteria

* Patients undergoing emergency surgery OR nephrectomy, liver and/or kidney transplantation
* Patients suffering from atrial fibrillation and/or sepsis (according to current Sepsis-3 definition)
* American Society of Anesthesiology (ASA) physical status classification V or VI
* Disability and/or other circumstances under which the patient is not able to understand the nature, significance and scope of the investigation
* Pregnancy at the time of surgery
* Patients without signed informed consent / data protection statement
* Patient participating in other interventional trials
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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IPPMed - Institut für Pharmakologie und Präventive Medizin GmbH

UNKNOWN

Sponsor Role collaborator

Edwards Lifesciences

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hôpital Lariboisière

Paris, , France

Site Status

Les Hôpitaux Universitaires de Strasbourg

Strasbourg, , France

Site Status

Marien Hospital Herne, University Hospital Ruhr-University Bochum

Herne, Rhine-Westphalia, Germany

Site Status

Justus Liebig University Giessen, University Hospital of Giessen and Marburg

Giessen, , Germany

Site Status

University Medical Center Hamburg Eppendorf

Hamburg, , Germany

Site Status

University Hospital Philipps-Universität Marburg, University Hospital of Giessen and Marburg

Marburg, , Germany

Site Status

Azienda Ospedaliero-Universitaria Ospedali Riuniti "Umberto I° General

Ancona, , Italy

Site Status

Azienda Ospedaliero-Universitaria Ospedali Riuniti di Ancona

Ancona, , Italy

Site Status

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Rome, , Italy

Site Status

Hospital Universitario Marqués de Valdecilla

Santander, Cantabria, Spain

Site Status

Hospital Universitario Infanta Leonor, Madrid

Madrid, , Spain

Site Status

York and Scarborough Teaching Hospitals NHS Foundation Trust

Clifton, York, United Kingdom

Site Status

Countries

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France Germany Italy Spain United Kingdom

Other Identifiers

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2021-08

Identifier Type: -

Identifier Source: org_study_id