Trial Outcomes & Findings for Study of RP-3500 (Camonsertib) With Niraparib or Olaparib in Advanced Solid Tumors (NCT NCT04972110)

NCT ID: NCT04972110

Last Updated: 2025-10-30

Results Overview

Treatment Related Treatment-Emergent Adverse Events (TRAE) with ≥3 CTCAE Grade

Recruitment status

TERMINATED

Study phase

PHASE1/PHASE2

Target enrollment

156 participants

Primary outcome timeframe

Start of treatment to 30 days post last dose, up to 23.7 months

Results posted on

2025-10-30

Participant Flow

Participant milestones

Participant milestones
Measure
Arm 1: 50mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
50 mg RP-3500 (camonsertib) taken QD (once a day) orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, weekly
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, 2 weeks on/1 week off
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
Arm 1: 70mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
70 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
50 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID (twice a day) orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 3d on/4d off, weekly
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 200 mg QD olaparib, 3d on/4 d off, weekly
50 mg RP-3500 (camonsertib) taken QD orally in combination with 200 mg olaparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
80 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, weekly
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, 2w on/1w off
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
Overall Study
STARTED
9
24
3
23
8
7
19
5
3
26
29
Overall Study
COMPLETED
1
4
1
0
0
0
1
1
1
0
0
Overall Study
NOT COMPLETED
8
20
2
23
8
7
18
4
2
26
29

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Study of RP-3500 (Camonsertib) With Niraparib or Olaparib in Advanced Solid Tumors

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Arm 1: 50mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=9 Participants
50 mg RP-3500 (camonsertib) taken QD (once a day) orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, weekly
n=24 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=3 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, 2 weeks on/1 week off
n=23 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
Arm 1: 70mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=8 Participants
70 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
n=7 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID (twice a day) orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 3d on/4d off, weekly
n=19 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 200 mg QD olaparib, 3d on/4 d off, weekly
n=5 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 200 mg olaparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
n=3 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, weekly
n=26 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, 2w on/1w off
n=29 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
Total
n=156 Participants
Total of all reporting groups
Age, Customized
Age
60.9 years
STANDARD_DEVIATION 13.51 • n=5 Participants
61.7 years
STANDARD_DEVIATION 7.70 • n=7 Participants
61.7 years
STANDARD_DEVIATION 15.18 • n=5 Participants
56.4 years
STANDARD_DEVIATION 9.01 • n=4 Participants
63.1 years
STANDARD_DEVIATION 12.14 • n=21 Participants
53.1 years
STANDARD_DEVIATION 14.24 • n=8 Participants
56.8 years
STANDARD_DEVIATION 14.60 • n=8 Participants
59.8 years
STANDARD_DEVIATION 12.40 • n=24 Participants
59.3 years
STANDARD_DEVIATION 21.08 • n=42 Participants
58.8 years
STANDARD_DEVIATION 13.38 • n=42 Participants
59.2 years
STANDARD_DEVIATION 13.73 • n=42 Participants
58.9 years
STANDARD_DEVIATION 12.25 • n=42 Participants
Sex: Female, Male
Female
6 Participants
n=5 Participants
20 Participants
n=7 Participants
2 Participants
n=5 Participants
19 Participants
n=4 Participants
8 Participants
n=21 Participants
3 Participants
n=8 Participants
12 Participants
n=8 Participants
2 Participants
n=24 Participants
1 Participants
n=42 Participants
15 Participants
n=42 Participants
16 Participants
n=42 Participants
104 Participants
n=42 Participants
Sex: Female, Male
Male
3 Participants
n=5 Participants
4 Participants
n=7 Participants
1 Participants
n=5 Participants
4 Participants
n=4 Participants
0 Participants
n=21 Participants
4 Participants
n=8 Participants
7 Participants
n=8 Participants
3 Participants
n=24 Participants
2 Participants
n=42 Participants
11 Participants
n=42 Participants
13 Participants
n=42 Participants
52 Participants
n=42 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
0 Participants
n=5 Participants
2 Participants
n=7 Participants
0 Participants
n=5 Participants
4 Participants
n=4 Participants
0 Participants
n=21 Participants
0 Participants
n=8 Participants
0 Participants
n=8 Participants
0 Participants
n=24 Participants
0 Participants
n=42 Participants
2 Participants
n=42 Participants
3 Participants
n=42 Participants
11 Participants
n=42 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
9 Participants
n=5 Participants
22 Participants
n=7 Participants
3 Participants
n=5 Participants
18 Participants
n=4 Participants
8 Participants
n=21 Participants
6 Participants
n=8 Participants
18 Participants
n=8 Participants
5 Participants
n=24 Participants
3 Participants
n=42 Participants
23 Participants
n=42 Participants
26 Participants
n=42 Participants
141 Participants
n=42 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
1 Participants
n=4 Participants
0 Participants
n=21 Participants
1 Participants
n=8 Participants
1 Participants
n=8 Participants
0 Participants
n=24 Participants
0 Participants
n=42 Participants
1 Participants
n=42 Participants
0 Participants
n=42 Participants
4 Participants
n=42 Participants

PRIMARY outcome

Timeframe: Start of treatment to 30 days post last dose, up to 23.7 months

Treatment Related Treatment-Emergent Adverse Events (TRAE) with ≥3 CTCAE Grade

Outcome measures

Outcome measures
Measure
Arm 1: 50mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=9 Participants
50 mg RP-3500 (camonsertib) taken QD (once a day) orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, weekly
n=24 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=3 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, 2 weeks on/1 week off
n=23 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
Arm 1: 70mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=8 Participants
70 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
n=7 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID (twice a day) orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 3d on/4d off, weekly
n=19 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 200 mg QD olaparib, 3d on/4 d off, weekly
n=5 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 200 mg olaparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
n=3 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, weekly
n=26 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, 2w on/1w off
n=29 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
Determine the Safety and Tolerability of Niraparib or Olaparib in Combination With RP-3500 in Patients With Molecularly Selected Solid Tumors
8 Participants
20 Participants
3 Participants
12 Participants
7 Participants
6 Participants
16 Participants
5 Participants
3 Participants
16 Participants
23 Participants

PRIMARY outcome

Timeframe: During 21 days (one cycle) from the initiation of the study treatment

Frequency of DLTs during the DLT observation period

Outcome measures

Outcome measures
Measure
Arm 1: 50mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=8 Participants
50 mg RP-3500 (camonsertib) taken QD (once a day) orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, weekly
n=22 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=3 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, 2 weeks on/1 week off
n=22 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
Arm 1: 70mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=8 Participants
70 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
n=6 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID (twice a day) orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 3d on/4d off, weekly
n=17 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 200 mg QD olaparib, 3d on/4 d off, weekly
n=4 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 200 mg olaparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
n=3 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, weekly
n=26 Participants
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, 2w on/1w off
n=27 Participants
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
Define the Recommended Phase 2 Dose (RP2D) of RP-3500 in Combination With Niraparib or Olaparib in Patients With Molecularly Selected Solid Tumors
1 Participants
1 Participants
3 Participants
1 Participants
1 Participants
3 Participants
6 Participants
1 Participants
2 Participants
0 Participants
3 Participants

Adverse Events

Arm 1: 50mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly

Serious events: 4 serious events
Other events: 9 other events
Deaths: 3 deaths

Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, weekly

Serious events: 8 serious events
Other events: 24 other events
Deaths: 10 deaths

Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly

Serious events: 2 serious events
Other events: 3 other events
Deaths: 0 deaths

Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, 2 weeks on/1 week off

Serious events: 7 serious events
Other events: 23 other events
Deaths: 8 deaths

Arm 1: 70mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, weekly

Serious events: 3 serious events
Other events: 8 other events
Deaths: 1 deaths

Arm 2: 50mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly

Serious events: 1 serious events
Other events: 7 other events
Deaths: 4 deaths

Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 3d on/4d off, weekly

Serious events: 11 serious events
Other events: 19 other events
Deaths: 10 deaths

Arm 2: 50mg QD camonsertib + 200 mg QD olaparib, 3d on/4 d off, weekly

Serious events: 2 serious events
Other events: 5 other events
Deaths: 1 deaths

Arm 2: 80mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly

Serious events: 1 serious events
Other events: 3 other events
Deaths: 1 deaths

Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, weekly

Serious events: 8 serious events
Other events: 26 other events
Deaths: 6 deaths

Arm 2: 80mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, 2w on/1w off

Serious events: 8 serious events
Other events: 27 other events
Deaths: 5 deaths

Serious adverse events

Serious adverse events
Measure
Arm 1: 50mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=9 participants at risk
50 mg RP-3500 (camonsertib) taken QD (once a day) orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, weekly
n=24 participants at risk
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=3 participants at risk
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, 2 weeks on/1 week off
n=23 participants at risk
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
Arm 1: 70mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, weekly
n=8 participants at risk
70 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
n=7 participants at risk
50 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID (twice a day) orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 3d on/4d off, weekly
n=19 participants at risk
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 200 mg QD olaparib, 3d on/4 d off, weekly
n=5 participants at risk
50 mg RP-3500 (camonsertib) taken QD orally in combination with 200 mg olaparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
n=3 participants at risk
80 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, weekly
n=26 participants at risk
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, 2w on/1w off
n=29 participants at risk
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
Nervous system disorders
Hemiparesis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Blood and lymphatic system disorders
Anaemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Blood and lymphatic system disorders
Febrile neutropenia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Blood and lymphatic system disorders
Neutrophil count decreased/ Neutropenia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Blood and lymphatic system disorders
Platelet count decreased/ Thrombocytopenia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Cardiac disorders
Acute coronary syndrome
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Cardiac disorders
Atrial fibrillation
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Cardiac disorders
Myocardial infarction
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Endocrine disorders
Adrenal insufficiency
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Abdominal pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.0%
3/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Constipation
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Gastrointestinal haemorrhage
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Large intestinal obstruction
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Nausea
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Obstruction gastric
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Small intestinal obstruction
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Vomiting
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Non-cardiac chest pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Pyrexia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Hepatobiliary disorders
Biliary obstruction
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Hepatobiliary disorders
Hepatic failure
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Bacteraemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
COVID-19
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Device related infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Pneumonia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Pneumonia fungal
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Sepsis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Skin infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Urinary tract infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Wound infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Fall
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Rib fracture
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Thermal burn
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Vascular pseudoaneurysm
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypokalaemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Back pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Muscular weakness
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Acute myeloid leukaemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Cancer pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Leukaemia
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastases to meninges
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Tumour haemorrhage
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Tumour pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Spinal cord compression
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Haematuria
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Dyspnoea
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Pleural effusion
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Pulmonary embolism
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Vascular disorders
Embolism
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events

Other adverse events

Other adverse events
Measure
Arm 1: 50mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=9 participants at risk
50 mg RP-3500 (camonsertib) taken QD (once a day) orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, weekly
n=24 participants at risk
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 3d on/4d off, weekly
n=3 participants at risk
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 1: 80mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, 2 weeks on/1 week off
n=23 participants at risk
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
Arm 1: 70mg QD camonsertib + 100mg QD niraparib, 2d on/5d off, weekly
n=8 participants at risk
70 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg niraparib taken QD orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
n=7 participants at risk
50 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID (twice a day) orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 3d on/4d off, weekly
n=19 participants at risk
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 200 mg QD olaparib, 3d on/4 d off, weekly
n=5 participants at risk
50 mg RP-3500 (camonsertib) taken QD orally in combination with 200 mg olaparib taken QD orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 150mg BID olaparib, 3d on/4d off, weekly
n=3 participants at risk
80 mg RP-3500 (camonsertib) taken QD orally in combination with 150 mg olaparib taken BID orally, same day on a 3 days on and 4 days off schedule for 3 weeks (21 day cycle)
Arm 2: 50mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, weekly
n=26 participants at risk
50 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 3 weeks (21 day cycle)
Arm 2: 80mg QD camonsertib + 100mg BID olaparib, 2d on/5d off, 2w on/1w off
n=29 participants at risk
80 mg RP-3500 (camonsertib) taken QD orally in combination with 100 mg olaparib taken BID orally, same day on a 2 days on and 5 days off schedule for 2 weeks on and 1 week off (21 day cycle)
General disorders and administration site conditions
Crying
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Urostomy complication
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Rotator cuff syndrome
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Sacral pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Epistaxis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Blood and lymphatic system disorders
Anaemia
88.9%
8/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
83.3%
20/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
100.0%
3/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
65.2%
15/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
75.0%
6/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
85.7%
6/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
89.5%
17/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
80.0%
4/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
100.0%
3/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
92.3%
24/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
65.5%
19/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Blood and lymphatic system disorders
Febrile neutropenia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Blood and lymphatic system disorders
Lymphopenia
22.2%
2/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
16.7%
4/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
28.6%
2/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
40.0%
2/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.8%
4/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Blood and lymphatic system disorders
Neutrophil count decreased/ Neutropenia
44.4%
4/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
62.5%
15/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
100.0%
3/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
21.7%
5/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
28.6%
2/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
73.7%
14/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
60.0%
3/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
100.0%
3/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
50.0%
13/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
72.4%
21/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Blood and lymphatic system disorders
Platelet count decreased/ Thrombocytopenia
33.3%
3/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
41.7%
10/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
100.0%
3/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.0%
3/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
57.1%
4/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
36.8%
7/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
40.0%
2/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
19.2%
5/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
37.9%
11/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Blood and lymphatic system disorders
WBC count decreased/ Leukopenia
33.3%
3/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
8/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
52.6%
10/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
60.0%
3/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
30.8%
8/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
34.5%
10/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Cardiac disorders
Atrial fibrillation
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Cardiac disorders
Cardiac discomfort
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Cardiac disorders
Cardiac failure
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Cardiac disorders
Cardiomyopathy
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Cardiac disorders
Palpitations
22.2%
2/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Cardiac disorders
Sinus bradycardia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Cardiac disorders
Sinus tachycardia
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
16.7%
4/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Ear and labyrinth disorders
Ear pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Ear and labyrinth disorders
Hypoacusis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Ear and labyrinth disorders
Tinnitus
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Ear and labyrinth disorders
Vertigo
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Endocrine disorders
Adrenal insufficiency
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Eye disorders
Dry eye
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Eye disorders
Eye pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Eye disorders
Eye swelling
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Eye disorders
Lacrimation increased
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Eye disorders
Photophobia
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Eye disorders
Vision blurred
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Eye disorders
Visual impairment
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Eye disorders
Vitreous floaters
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Abdominal discomfort
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Abdominal distension
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
3/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.0%
3/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
40.0%
2/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Abdominal pain
22.2%
2/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
16.7%
4/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
30.4%
7/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
25.0%
2/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Abdominal pain lower
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
25.0%
2/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Abdominal pain upper
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Anal incontinence
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Ascites
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Change of bowel habit
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Colitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Constipation
22.2%
2/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
41.7%
10/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
21.7%
5/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
19.2%
5/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.7%
6/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Crohn's disease
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Dental caries
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Diarrhoea
33.3%
3/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
29.2%
7/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
21.7%
5/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
25.0%
2/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
28.6%
2/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.8%
3/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
23.1%
6/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
17.2%
5/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Dry mouth
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
3/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
25.0%
2/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Duodenitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Dyspepsia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Dysphagia
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Flatulence
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Gastrointestinal disorder
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Gastrointestinal wall thickening
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Gastrooesophageal reflux disease
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Gingival bleeding
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Haematochezia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Hiatus hernia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Large intestinal haemorrhage
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Large intestinal obstruction
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Large intestinal ulcer
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Nausea
55.6%
5/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
37.5%
9/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
47.8%
11/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
62.5%
5/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
26.3%
5/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
40.0%
2/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
66.7%
2/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
26.9%
7/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
41.4%
12/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Obstruction gastric
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Oesophagitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Oral pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Proctalgia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Rectal ulcer
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Retching
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Small intestinal obstruction
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Stomatitis
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.0%
3/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.8%
3/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Toothache
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Varices oesophageal
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Gastrointestinal disorders
Vomiting
22.2%
2/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
8/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
47.8%
11/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
25.0%
2/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
28.6%
2/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
40.0%
2/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.4%
4/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
17.2%
5/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Asthenia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Axillary pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Chest discomfort
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Chills
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Deformity
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Early satiety
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Face oedema
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Fatigue
44.4%
4/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
70.8%
17/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
66.7%
2/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
39.1%
9/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
37.5%
3/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
28.6%
2/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
36.8%
7/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
60.0%
3/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
66.7%
2/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
34.6%
9/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
34.5%
10/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Influenza like illness
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Localised oedema
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Malaise
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Mucosal inflammation
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Non-cardiac chest pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Oedema peripheral
22.2%
2/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
3/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.8%
3/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.8%
4/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
25.0%
2/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Peripheral swelling
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Pyrexia
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
66.7%
2/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Suprapubic pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Swelling face
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
General disorders and administration site conditions
Temperature intolerance
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Immune system disorders
Hypersensitivity
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Acute sinusitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Bronchitis
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
COVID-19
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.8%
5/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Cellulitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Chronic sinusitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Conjunctivitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Cystitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Device related infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Folliculitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Gingivitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Lower respiratory tract infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Ludwig angina
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Osteomyelitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Periorbital cellulitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Pneumonia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Pneumonia fungal
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Pseudomonas infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Rash pustular
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Sinusitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Skin infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Streptococcal infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Tooth abscess
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Tooth infection
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Upper respiratory tract infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
3/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.3%
3/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Urinary tract infection
22.2%
2/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
3/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Vaginal infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Infections and infestations
Wound infection
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Contusion
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Fall
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
3/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Foot fracture
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Fractured sacrum
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Head injury
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Incision site inflammation
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Lower limb fracture
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Meniscus injury
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Muscle strain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Pelvic fracture
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Post procedural bile leak
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Rib fracture
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Skin abrasion
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Skin laceration
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Skin wound
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Soft tissue injury
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Spinal compression fracture
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Spinal fracture
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Injury, poisoning and procedural complications
Vascular access complication
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Alanine aminotransferase increased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
28.6%
2/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
40.0%
2/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
11.5%
3/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Aspartate aminotransferase increased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
60.0%
3/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.4%
4/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.8%
4/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Blood albumin increased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Blood alkaline phosphatase increased
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
60.0%
3/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
11.5%
3/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.3%
3/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Blood bicarbonate decreased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Blood bilirubin increased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
40.0%
2/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Blood chloride decreased
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Blood creatinine increased
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
28.6%
2/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.3%
3/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Blood lactate dehydrogenase increased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Blood pressure diastolic increased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Blood urea increased
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Gamma-glutamyltransferase increased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Heart rate increased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Neutrophil count increased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Nitrite urine present
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Protein total decreased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Thyroxine increased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Urine analysis abnormal
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Weight decreased
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
Weight increased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Investigations
White blood cells urine positive
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Decreased appetite
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.8%
5/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
66.7%
2/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
25.0%
2/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
21.1%
4/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
60.0%
3/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.4%
4/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.8%
4/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Dehydration
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
16.7%
4/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.8%
3/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypercalcaemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hyperglycaemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hyperkalaemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypermagnesaemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypernatraemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hyperphosphataemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hyperuricaemia
22.2%
2/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypoalbuminaemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
40.0%
2/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypocalcaemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypoglycaemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypokalaemia
22.2%
2/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypomagnesaemia
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hyponatraemia
22.2%
2/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
3/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
40.0%
2/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypophagia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypophosphataemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Hypouricaemia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Increased appetite
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Metabolism and nutrition disorders
Vitamin D deficiency
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Arthralgia
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.8%
3/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.4%
4/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.8%
4/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Arthritis
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Back pain
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
29.2%
7/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.0%
3/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.4%
4/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
17.2%
5/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Flank pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Groin pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Intervertebral disc degeneration
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Joint stiffness
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Joint swelling
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Muscle spasms
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
3/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
25.0%
2/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
66.7%
2/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Muscle tightness
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Muscular weakness
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
17.4%
4/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Musculoskeletal chest pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Musculoskeletal discomfort
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Musculoskeletal stiffness
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Myalgia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Neck pain
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.3%
3/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Osteonecrosis of jaw
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Pain in extremity
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
23.1%
6/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.3%
3/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Pain in jaw
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Plantar fasciitis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Musculoskeletal and connective tissue disorders
Soft tissue mass
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Cancer pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Metastases to central nervous system
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Neoplasms benign, malignant and unspecified (incl cysts and polyps)
Tumour pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Aphasia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Aura
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Brain fog
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Dizziness
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
17.4%
4/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
25.0%
2/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.8%
3/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.8%
4/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Dysarthria
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Dysgeusia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
25.0%
2/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Dyskinesia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Encephalopathy
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Extrapyramidal disorder
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Headache
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
29.2%
7/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
26.1%
6/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
28.6%
2/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.8%
3/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.4%
4/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.8%
4/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Hypoaesthesia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Lethargy
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Migraine
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Paraesthesia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Peripheral sensory neuropathy
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Presyncope
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Seizure
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Syncope
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.5%
2/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Taste disorder
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Toxic encephalopathy
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Nervous system disorders
Vocal cord paralysis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Psychiatric disorders
Agitation
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Psychiatric disorders
Anxiety
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
3/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
10.3%
3/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Psychiatric disorders
Confusional state
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Psychiatric disorders
Delirium
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Psychiatric disorders
Depression
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Psychiatric disorders
Emotional distress
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Psychiatric disorders
Insomnia
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.8%
5/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
17.4%
4/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.8%
4/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Psychiatric disorders
Mood swings
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Chronic kidney disease
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Dysuria
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Haematuria
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Hydronephrosis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Micturition urgency
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Pollakiuria
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Proteinuria
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Urge incontinence
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Urinary incontinence
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Urinary retention
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Urinary tract pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Renal and urinary disorders
Urine flow decreased
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Reproductive system and breast disorders
Breast disorder
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Reproductive system and breast disorders
Breast pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Reproductive system and breast disorders
Erectile dysfunction
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Reproductive system and breast disorders
Pelvic pain
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Reproductive system and breast disorders
Penile discomfort
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Reproductive system and breast disorders
Vaginal discharge
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Reproductive system and breast disorders
Vaginal haemorrhage
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Cough
33.3%
3/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
21.1%
4/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
66.7%
2/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Dry throat
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Dysphonia
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Dyspnoea
44.4%
4/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.8%
5/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
66.7%
2/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
13.0%
3/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
37.5%
3/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
28.6%
2/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.8%
3/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
66.7%
2/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
11.5%
3/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Dyspnoea exertional
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
15.8%
3/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Haemoptysis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Laryngospasm
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Lung infiltration
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Nasal congestion
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Oropharyngeal pain
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Pneumothorax
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Productive cough
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
6.9%
2/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Pulmonary embolism
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Respiratory failure
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Rhinitis allergic
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Rhinorrhoea
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Upper-airway cough syndrome
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Respiratory, thoracic and mediastinal disorders
Wheezing
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Alopecia
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Dandruff
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Dermal cyst
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Dry skin
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Erythema
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Hyperhidrosis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Nail disorder
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Photosensitivity reaction
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Pruritus
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Rash
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
7.7%
2/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Rash maculo-papular
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Sensitive skin
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Skin induration
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Skin ulcer
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Skin and subcutaneous tissue disorders
Urticaria
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Vascular disorders
Aneurysm
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Vascular disorders
Deep vein thrombosis
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Vascular disorders
Embolism
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Vascular disorders
Flushing
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.3%
1/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Vascular disorders
Hot flush
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.4%
1/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Vascular disorders
Hypertension
11.1%
1/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
4.2%
1/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
12.5%
1/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
14.3%
1/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
20.0%
1/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Vascular disorders
Hypotension
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.3%
2/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
8.7%
2/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
5.3%
1/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
33.3%
1/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
Vascular disorders
Orthostatic hypotension
0.00%
0/9 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/24 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/23 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/8 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/7 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/19 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/5 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/3 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
3.8%
1/26 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events
0.00%
0/29 • Start of treatment to 30 days post lase dose, up to 34.7 months for Serious adverse events; Start of treatment to 30 days post last dose, up to 23.7 months for other adverse events

Additional Information

Repare Therapeutics Medical Monitor

Repare Therapeutics Inc

Phone: 1 (857) 340-5402

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place