Trial Outcomes & Findings for Producing a Fully Asynchronous Online Savvy Program (NCT NCT04951037)

NCT ID: NCT04951037

Last Updated: 2024-04-16

Results Overview

The CES-D is a 20-item self-report instrument asking respondents if they have experienced symptoms of depression during the past week. Responses are given on a scale of 0 to 3 where "rarely" = 0 and "most of the time" = 3. Total scores range from 0 to 60 and higher scores indicate greater symptoms of depression.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

60 participants

Primary outcome timeframe

Baseline, Month 2, Month 3

Results posted on

2024-04-16

Participant Flow

Participants were recruited in Atlanta, USA. Participant enrollment began September 15, 2021 and all follow-up assessments were completed by September 2, 2022.

Participant milestones

Participant milestones
Measure
Fully Asynchronous Online Savvy Program
Family caregivers of a person living with dementia (PLWD) taking part in a fully asynchronous online caregiver education program. The intervention is a fully online, self-administered psychoeducational program designed to enhance caregiver mastery for family and friends providing unpaid care for living with Alzheimer's and similar dementia disorders. Participants are asked to engage with a fully online version of Tele-Savvy for 42 days.
Overall Study
STARTED
60
Overall Study
Completed Month 2 Assessment
46
Overall Study
Completed Month 3 Assessment
39
Overall Study
COMPLETED
29
Overall Study
NOT COMPLETED
31

Reasons for withdrawal

Reasons for withdrawal
Measure
Fully Asynchronous Online Savvy Program
Family caregivers of a person living with dementia (PLWD) taking part in a fully asynchronous online caregiver education program. The intervention is a fully online, self-administered psychoeducational program designed to enhance caregiver mastery for family and friends providing unpaid care for living with Alzheimer's and similar dementia disorders. Participants are asked to engage with a fully online version of Tele-Savvy for 42 days.
Overall Study
Lost to Follow-up
16
Overall Study
Withdrawal by Subject
5
Overall Study
Completed study assessments but did not complete the intervention
10

Baseline Characteristics

Producing a Fully Asynchronous Online Savvy Program

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Fully Asynchronous Online Savvy Program
n=60 Participants
Family caregivers of PLWD taking part in a fully asynchronous online caregiver education program. The intervention is a fully online, self-administered psychoeducational program designed to enhance caregiver mastery for family and friends providing unpaid care for living with Alzheimer's and similar dementia disorders. Participants are asked to engage with a fully online version of Tele-Savvy for 42 days.
Age, Continuous
58.217 years
STANDARD_DEVIATION 14.438 • n=93 Participants
Sex/Gender, Customized
Female
50 Participants
n=93 Participants
Sex/Gender, Customized
Male
9 Participants
n=93 Participants
Sex/Gender, Customized
Non-binary
1 Participants
n=93 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
4 Participants
n=93 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
55 Participants
n=93 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
1 Participants
n=93 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=93 Participants
Race (NIH/OMB)
Asian
0 Participants
n=93 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=93 Participants
Race (NIH/OMB)
Black or African American
7 Participants
n=93 Participants
Race (NIH/OMB)
White
48 Participants
n=93 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=93 Participants
Race (NIH/OMB)
Unknown or Not Reported
5 Participants
n=93 Participants
Region of Enrollment
United States
60 Participants
n=93 Participants

PRIMARY outcome

Timeframe: Baseline, Month 2, Month 3

Population: This analysis includes values for the subset of 29 participants who completed the study intervention and the study assessments. Some participants did not complete the study intervention according to study timelines, but they did remain in the study and complete the assessments. In order to report all available data, values are also included for all study participants who completed the survey at the indicated time points, regardless of whether they completed the intervention.

The CES-D is a 20-item self-report instrument asking respondents if they have experienced symptoms of depression during the past week. Responses are given on a scale of 0 to 3 where "rarely" = 0 and "most of the time" = 3. Total scores range from 0 to 60 and higher scores indicate greater symptoms of depression.

Outcome measures

Outcome measures
Measure
Fully Asynchronous Online Savvy Program
n=60 Participants
Family caregivers of PLWD taking part in a fully asynchronous online caregiver education program. The intervention is a fully online, self-administered psychoeducational program designed to enhance caregiver mastery for family and friends providing unpaid care for living with Alzheimer's and similar dementia disorders. Participants are asked to engage with a fully online version of Tele-Savvy for 42 days.
Center for Epidemiologic Studies - Depression (CES-D) Score
Baseline among those who completed the Online Savvy Program
11.483 score on a scale
Standard Deviation 11.009
Center for Epidemiologic Studies - Depression (CES-D) Score
Month 2 among those who completed the Online Savvy Program
9.345 score on a scale
Standard Deviation 6.360
Center for Epidemiologic Studies - Depression (CES-D) Score
Month 3 among those who completed the Online Savvy Program
8.964 score on a scale
Standard Deviation 8.149
Center for Epidemiologic Studies - Depression (CES-D) Score
Baseline among those who completed the survey
14.317 score on a scale
Standard Deviation 11.058
Center for Epidemiologic Studies - Depression (CES-D) Score
Month 2 among those who completed the survey
10.848 score on a scale
Standard Deviation 8.200
Center for Epidemiologic Studies - Depression (CES-D) Score
Month 3 among those who completed the survey
10.132 score on a scale
Standard Deviation 8.612

PRIMARY outcome

Timeframe: Baseline, Month 2, Month 3

Population: This analysis includes values for the subset of 29 participants who completed the study intervention and the study assessments. Some participants did not complete the study intervention according to study timelines, but they did remain in the study and complete the assessments. In order to report all available data, values are also included for all study participants who completed the survey at the indicated time points, regardless of whether they completed the intervention.

The Zarit Burden Interview is a 22-item scale of objective and subjective caregiver burden. Responses are given on a 5-point scale where 0 = never and 4 = nearly always. Total scores range from 0 to 88 where higher scores indicate greater feelings of being burdened with providing care.

Outcome measures

Outcome measures
Measure
Fully Asynchronous Online Savvy Program
n=60 Participants
Family caregivers of PLWD taking part in a fully asynchronous online caregiver education program. The intervention is a fully online, self-administered psychoeducational program designed to enhance caregiver mastery for family and friends providing unpaid care for living with Alzheimer's and similar dementia disorders. Participants are asked to engage with a fully online version of Tele-Savvy for 42 days.
Zarit Burden Interview Score
Baseline among those who completed the Online Savvy Program
31.207 score on a scale
Standard Deviation 12.957
Zarit Burden Interview Score
Month 2 among those who completed the Online Savvy Program
29.138 score on a scale
Standard Deviation 10.395
Zarit Burden Interview Score
Month 3 among those who completed the Online Savvy Program
26.296 score on a scale
Standard Deviation 9.474
Zarit Burden Interview Score
Baseline among those who completed the survey
35.050 score on a scale
Standard Deviation 14.274
Zarit Burden Interview Score
Month 2 among those who completed the survey
31.239 score on a scale
Standard Deviation 10.754
Zarit Burden Interview Score
Month 3 among those who completed the survey
28.730 score on a scale
Standard Deviation 10.235

PRIMARY outcome

Timeframe: Baseline, Month 2, Month 3

Population: This analysis includes values for the subset of 29 participants who completed the study intervention and the study assessments. Some participants did not complete the study intervention according to study timelines, but they did remain in the study and complete the assessments. In order to report all available data, values are also included for all study participants who completed the survey at the indicated time points, regardless of whether they completed the intervention.

The STAI is a 20-item self-report scale of positive and negative anxiety experiences. Responses are given on a 4-point scale where 1 = not at all and 4 = very much so. Total scores range from 20 to 80 and higher scores indicate greater anxiety.

Outcome measures

Outcome measures
Measure
Fully Asynchronous Online Savvy Program
n=60 Participants
Family caregivers of PLWD taking part in a fully asynchronous online caregiver education program. The intervention is a fully online, self-administered psychoeducational program designed to enhance caregiver mastery for family and friends providing unpaid care for living with Alzheimer's and similar dementia disorders. Participants are asked to engage with a fully online version of Tele-Savvy for 42 days.
State-Trait Anxiety Inventory (STAI) Score
Baseline among those who completed the Online Savvy Program
31.793 score on a scale
Standard Deviation 9.777
State-Trait Anxiety Inventory (STAI) Score
Month 2 among those who completed the Online Savvy Program
31.793 score on a scale
Standard Deviation 8.104
State-Trait Anxiety Inventory (STAI) Score
Month 3 among those who completed the Online Savvy Program
29.893 score on a scale
Standard Deviation 8.230
State-Trait Anxiety Inventory (STAI) Score
Baseline among those who completed the survey
34.862 score on a scale
Standard Deviation 11.190
State-Trait Anxiety Inventory (STAI) Score
Month 2 among those who completed the survey
31.761 score on a scale
Standard Deviation 9.053
State-Trait Anxiety Inventory (STAI) Score
Month 3 among those who completed the survey
31.103 score on a scale
Standard Deviation 9.167

PRIMARY outcome

Timeframe: Baseline, Month 2, Month 3

Population: Participants with incomplete responses were removed from this analysis. Of the 29 participants who completed the study intervention and assessments, 4 had missing responses for this survey at any time point, resulting in 25 participants analyzed. Values are also included for all study participants responding to surveys at the indicated time points, even if they did not complete the intervention; of these 8 had missing responses on this survey at Baseline and 1 had missing responses at Month 2.

The Caregiving Mastery instrument assesses caregiver mastery of 3 different realms of caregiving situations: Relational Deprivation, Caregiving Competence, and Management of Situation. The Caregiving Competence subscale asks caregivers about their thoughts about the caregiving they provide with 4 items where responses are given on a 4-point scale where "not at all" = 1 and "completely" or "very" = 4. Total scores range from 4 to 16 where higher scores indicate greater feelings of competence with caregiving.

Outcome measures

Outcome measures
Measure
Fully Asynchronous Online Savvy Program
n=52 Participants
Family caregivers of PLWD taking part in a fully asynchronous online caregiver education program. The intervention is a fully online, self-administered psychoeducational program designed to enhance caregiver mastery for family and friends providing unpaid care for living with Alzheimer's and similar dementia disorders. Participants are asked to engage with a fully online version of Tele-Savvy for 42 days.
Caregiver Mastery Scale - Caregiving Competence Score
Baseline among those who completed the survey
11.481 score on a scale
Standard Deviation 2.330
Caregiver Mastery Scale - Caregiving Competence Score
Month 2 among those who completed the survey
12.689 score on a scale
Standard Deviation 1.998
Caregiver Mastery Scale - Caregiving Competence Score
Month 3 among those who completed the survey
13.026 score on a scale
Standard Deviation 2.146
Caregiver Mastery Scale - Caregiving Competence Score
Baseline among those who completed the Online Savvy Program
12.160 score on a scale
Standard Deviation 1.700
Caregiver Mastery Scale - Caregiving Competence Score
Month 2 among those who completed the Online Savvy Program
12.821 score on a scale
Standard Deviation 1.945
Caregiver Mastery Scale - Caregiving Competence Score
Month 3 among those who completed the Online Savvy Program
13.143 score on a scale
Standard Deviation 2.085

PRIMARY outcome

Timeframe: Baseline, Month 2, Month 3

Population: This analysis includes values for the subset of 29 participants who completed the study intervention and the study assessments. Some participants did not complete the study intervention according to study timelines, but they did remain in the study and complete the assessments. In order to report all available data, values are also included for all study participants who completed the survey at the indicated time points, regardless of whether they completed the intervention.

The RMBPC is a 24-item scale reporting on frequency of disturbing care recipient behaviors and severity or caregiver reactions to these behaviors. Respondents indicate how frequently problems have occurred on a 5-point scale where 0 = never occurred and 4 = daily or more often. Total frequency scores range from 0 to 96 with higher scores indicating greater frequency of memory and behavior problems exhibited by the PLWD.

Outcome measures

Outcome measures
Measure
Fully Asynchronous Online Savvy Program
n=60 Participants
Family caregivers of PLWD taking part in a fully asynchronous online caregiver education program. The intervention is a fully online, self-administered psychoeducational program designed to enhance caregiver mastery for family and friends providing unpaid care for living with Alzheimer's and similar dementia disorders. Participants are asked to engage with a fully online version of Tele-Savvy for 42 days.
Revised Memory and Behavior Problem Checklist (RMBPC) Frequency Score
Baseline among those who completed the Online Savvy Program
40.276 score on a scale
Standard Deviation 12.015
Revised Memory and Behavior Problem Checklist (RMBPC) Frequency Score
Month 2 among those who completed the Online Savvy Program
36.345 score on a scale
Standard Deviation 9.529
Revised Memory and Behavior Problem Checklist (RMBPC) Frequency Score
Month 3 among those who completed the Online Savvy Program
34.786 score on a scale
Standard Deviation 9.796
Revised Memory and Behavior Problem Checklist (RMBPC) Frequency Score
Baseline among those who completed the survey
40.407 score on a scale
Standard Deviation 13.849
Revised Memory and Behavior Problem Checklist (RMBPC) Frequency Score
Month 2 among those who completed the survey
35.739 score on a scale
Standard Deviation 10.784
Revised Memory and Behavior Problem Checklist (RMBPC) Frequency Score
Month 3 among those who completed the survey
34.897 score on a scale
Standard Deviation 9.784

PRIMARY outcome

Timeframe: Baseline, Month 2, Month 3

Population: This analysis includes values for the subset of 29 participants who completed the study intervention and the study assessments. Some participants did not complete the study intervention according to study timelines, but they did remain in the study and complete the assessments. In order to report all available data, values are also included for all study participants who completed the survey at the indicated time points, regardless of whether they completed the intervention.

The RMBPC is a 24-item scale reporting on frequency of disturbing care recipient behaviors and severity or caregiver reactions to these behaviors. Respondents indicate the degree to which problems have bothered or upset them on a 5-point scale where 0 = not at all and 4 = extremely. Total reaction scores range from 0 to 96 with higher scores indicating more bothered or upset by memory and behavior problems exhibited by the PLWD.

Outcome measures

Outcome measures
Measure
Fully Asynchronous Online Savvy Program
n=60 Participants
Family caregivers of PLWD taking part in a fully asynchronous online caregiver education program. The intervention is a fully online, self-administered psychoeducational program designed to enhance caregiver mastery for family and friends providing unpaid care for living with Alzheimer's and similar dementia disorders. Participants are asked to engage with a fully online version of Tele-Savvy for 42 days.
Revised Memory and Behavior Problem Checklist (RMBPC) Reaction Score
Baseline among those who completed the Online Savvy Program
18.483 score on a scale
Standard Deviation 10.534
Revised Memory and Behavior Problem Checklist (RMBPC) Reaction Score
Month 2 among those who completed the Online Savvy Program
12.828 score on a scale
Standard Deviation 7.016
Revised Memory and Behavior Problem Checklist (RMBPC) Reaction Score
Month 3 among those who completed the Online Savvy Program
12.893 score on a scale
Standard Deviation 7.420
Revised Memory and Behavior Problem Checklist (RMBPC) Reaction Score
Baseline among those who completed the survey
20.167 score on a scale
Standard Deviation 12.238
Revised Memory and Behavior Problem Checklist (RMBPC) Reaction Score
Month 2 among those who completed the survey
12.522 score on a scale
Standard Deviation 7.453
Revised Memory and Behavior Problem Checklist (RMBPC) Reaction Score
Month 3 among those who completed the survey
13.132 score on a scale
Standard Deviation 7.977

Adverse Events

Fully Asynchronous Online Savvy Program

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Fayron Epps, PhD, RN

Emory University

Phone: 404-727-6936

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place