Risk Factors and the Effect of Plasma Exchange on Prognosis of Pregnancy-related Thrombotic Microangiopathies
NCT ID: NCT04949698
Last Updated: 2021-07-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
50 participants
OBSERVATIONAL
2021-08-01
2022-08-01
Brief Summary
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Detailed Description
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Design: A retrospective analysis of pregnant patients admitted to the ICU from 2015 to 2019. According to the outcome indicator of the occurrence of pregnancy-related thrombotic microangiopathies, they were divided into thrombotic microangiopathies group and non-thrombotic microangiopathies group. Patients in the pregnancy-related thrombotic microangiopathy group were divided into plasma exchange combined non-plasma exchange group according to whether they received plasma exchange. Collect the clinical data of the patients, and analyze the data using SPSS 1 7.0 statistical software package. The measurement data were compared by paired t test and one-way analysis of variance; the count data were compared by χ2 test. Compare the differences of the indicators between the two groups and analyze the risk factors of pregnancy-related thrombotic microangiopathies. Then compare whether there is a difference in the prognosis between the plasma exchange group and the non-plasma exchange group."
Conditions
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Study Design
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CASE_CONTROL
RETROSPECTIVE
Study Groups
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No TMA
parturients without thrombotic microangiopathies
plasma exchange
Plasma exchange was performed daily for five times or until platelet level returned to normal
TMA with plasma exchange
parturients with thrombotic microangiopathies, and treated with plasma exchange
plasma exchange
Plasma exchange was performed daily for five times or until platelet level returned to normal
TMA without plasma exchange
parturients with thrombotic microangiopathies, but not treated with plasma exchange
plasma exchange
Plasma exchange was performed daily for five times or until platelet level returned to normal
Interventions
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plasma exchange
Plasma exchange was performed daily for five times or until platelet level returned to normal
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
ALL
No
Sponsors
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Peking University Third Hospital
OTHER
Responsible Party
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Principal Investigators
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Min Yi, chief physician
Role: STUDY_DIRECTOR
Peking University Third Hospital
Central Contacts
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Other Identifiers
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LM2020304
Identifier Type: -
Identifier Source: org_study_id
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