Changes in Cerebral Oxygenation and Cognitive Functions
NCT ID: NCT04948957
Last Updated: 2021-07-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
40 participants
OBSERVATIONAL
2014-03-01
2016-08-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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esmolol (Group E)
Esmolol
nitroglycerin (Group N)
Nitroglycerin
Interventions
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Esmolol
Nitroglycerin
Eligibility Criteria
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Inclusion Criteria
* patients with ASA physical status of I-II
* aged 18-65 years
Exclusion Criteria
* ASA \> II
* coagulation disorders
* history of cardiovascular and cerebrovascular disease
* poor Blood Pressure control
* anemia, pregnancy, addiction to opioids
* body mass index (BMI) \> 35
* intraoperative systolic BP \< 65 mmHg
* surgical duration less than 30 minutes or more than 160 minutes
* need for an intraoperative sympathomimetic drug and the use of other hypotensive drugs
* preoperative Mini-Mental State Examination (MMSE) score of 23 or less.
18 Years
65 Years
ALL
Yes
Sponsors
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Zonguldak Bulent Ecevit University
OTHER
Responsible Party
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Bengü Gülhan Aydin
Associate Professor
Locations
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Zonguldak Bülent Ecevit University Medicine Faculty
Zonguldak, Kozlu, Turkey (Türkiye)
Countries
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Other Identifiers
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2013-81-03/09
Identifier Type: -
Identifier Source: org_study_id
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