Efficacy of Epidural Analgesia in Lower Extremity Osteosarcoma
NCT ID: NCT04945512
Last Updated: 2021-11-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
28 participants
INTERVENTIONAL
2021-11-07
2022-09-20
Brief Summary
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Detailed Description
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Patients in the first group will be provided with preoperative and peroperative analgesia with an epidural catheter. The second group patient will be get no block. Afterwards, both groups will be operated under similar general anesthesia conditions. A patient-controlled analgesia device will be attached to each group of participants and their postoperative follow-up will be made.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Study group; Epidural catheter and PCA
Epidural catheter will be placed in the preoperative period. After induction, 10 ml of 0.25% bupivacaine will be administered through the epidural catheter and bupivacaine PCA will be started.
Epidural Analgesia
In the anesthesia preparation room, an epidutal catheter will be placed with a toue needle through the L4-5 spinal space. After induction of general anesthesia, 10 ml of 0.25% bupivacaine will be injected through the epidural catheter.Afterwards, peroperative and postoperative analgesia will be provided with epidural PCA.
Control group; No block, IC PCA
Postoperative pain control will be achieved with intravenous morphine PCA.
No interventions assigned to this group
Interventions
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Epidural Analgesia
In the anesthesia preparation room, an epidutal catheter will be placed with a toue needle through the L4-5 spinal space. After induction of general anesthesia, 10 ml of 0.25% bupivacaine will be injected through the epidural catheter.Afterwards, peroperative and postoperative analgesia will be provided with epidural PCA.
Eligibility Criteria
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Inclusion Criteria
* age older than 18 years and younger than 80 years,
* undergoing lower extremity osteosarcoma surgery
* the American Society of Anesthesiologist (ASA) physical status of I-II-III
Exclusion Criteria
* coagulation disorder
* patients with central nervous system related disease
* septic patients
18 Years
80 Years
ALL
No
Sponsors
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Istanbul University
OTHER
Responsible Party
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Nur Canbolat
Principle Invastigator, M.D.
Principal Investigators
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Gizem Toydemir, MD
Role: PRINCIPAL_INVESTIGATOR
Istanbul Unıversity, Istanbul Faculty of Medicine, Anesthesiology
Locations
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Istanbul University, Faculty of Medicine
Istanbul, Fatih, Turkey (Türkiye)
Countries
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Central Contacts
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Facility Contacts
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Nur Canbolat, MD
Role: primary
Mehmet Büget, Assoc. Prof
Role: backup
References
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Rawal N. Current issues in postoperative pain management. Eur J Anaesthesiol. 2016 Mar;33(3):160-71. doi: 10.1097/EJA.0000000000000366.
Weinbroum AA. Superiority of postoperative epidural over intravenous patient-controlled analgesia in orthopedic oncologic patients. Surgery. 2005 Nov;138(5):869-76. doi: 10.1016/j.surg.2005.05.004.
Other Identifiers
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2020/1831
Identifier Type: -
Identifier Source: org_study_id