Trial Outcomes & Findings for Robotic Hand Orthosis Providing Grasp Assistance for Patients With Brachial Plexus Injuries (NCT NCT04939233)

NCT ID: NCT04939233

Last Updated: 2025-10-17

Results Overview

Southampton Hand Assessment Procedure (SHAP) Construct Measured: Functional hand performance based on prehensile and Activities of Daily Living (ADL) tasks. Structure: 6 Abstract Object Tasks (grip patterns). The five most used grasp types in ADLs were selected for the experiments, which include cylinder grasp, sphere grasp, tip grasp, tripod grasp, and lateral grasp. We selected ten objects that belong to different grasp types for the experiments. Each object was grasped for five times by each participant. Scoring: Successful vs unsuccessful grasps with 10 different objects Interpretation: Successful grasps with 10 different objects

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

3 participants

Primary outcome timeframe

The total expected time for the study is about 2 hours.

Results posted on

2025-10-17

Participant Flow

Participant milestones

Participant milestones
Measure
Exoskeleton Glove
Perform a feasibility trial of the robotic orthosis device by providing it to a small cohort of adult patients suffering from paralysis due to a brachial plexus injury. Exoskeleton glove: A robotic hand orthosis (exoskeleton glove) will have been developed that is able to naturalistically bend the finger joints of the individuals based on intuitive voice commands
Overall Study
STARTED
3
Overall Study
COMPLETED
3
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Exoskeleton Glove
n=3 Participants
Perform a feasibility trial of the robotic orthosis device by providing it to a small cohort of adult patients suffering from paralysis due to a brachial plexus injury. Exoskeleton glove: A robotic hand orthosis (exoskeleton glove) will have been developed that is able to naturalistically bend the finger joints of the individuals based on intuitive voice commands
Age, Categorical
<=18 years
0 Participants
n=3 Participants
Age, Categorical
Between 18 and 65 years
3 Participants
n=3 Participants
Age, Categorical
>=65 years
0 Participants
n=3 Participants
Age, Continuous
30 years
STANDARD_DEVIATION 0.82 • n=3 Participants
Sex: Female, Male
Female
1 Participants
n=3 Participants
Sex: Female, Male
Male
2 Participants
n=3 Participants
Region of Enrollment
United States
3 participants
n=3 Participants

PRIMARY outcome

Timeframe: The total expected time for the study is about 2 hours.

Southampton Hand Assessment Procedure (SHAP) Construct Measured: Functional hand performance based on prehensile and Activities of Daily Living (ADL) tasks. Structure: 6 Abstract Object Tasks (grip patterns). The five most used grasp types in ADLs were selected for the experiments, which include cylinder grasp, sphere grasp, tip grasp, tripod grasp, and lateral grasp. We selected ten objects that belong to different grasp types for the experiments. Each object was grasped for five times by each participant. Scoring: Successful vs unsuccessful grasps with 10 different objects Interpretation: Successful grasps with 10 different objects

Outcome measures

Outcome measures
Measure
Exoskeleton Glove
n=3 Participants
Perform a feasibility trial of the robotic orthosis device by providing it to a small cohort of adult patients suffering from paralysis due to a brachial plexus injury. Exoskeleton glove: A robotic hand orthosis (exoskeleton glove) will have been developed that is able to naturalistically bend the finger joints of the individuals based on intuitive voice commands
Number of Successful Grasp Trials Per Participant Using Robotic Hand Orthosis
13.2 Number of successful grabs of an object
Interval 0.0 to 15.0

Adverse Events

Exoskeleton Glove

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Pinhas Ben-Tzvi

Departments of Mechanical Engineering and Electrical and Computer Engineering, Virginia Tech

Phone: NA

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place