Trial Outcomes & Findings for Virtual Reality Biofeedback for Postpartum Anxiety and Depression (NCT NCT04925765)

NCT ID: NCT04925765

Last Updated: 2024-04-17

Results Overview

Patient response to the feasibility of VR use. The question asked was, "I was able to do the session without difficulty," which was measured on a Likert Scale of 1-5. A score of 1 is indicative of great difficulty present and a score of 5 is indicative of no difficulty present. Outcome measurement is presented as an averaged score with standard deviation among participating patients.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

6 participants

Primary outcome timeframe

Completed immediately after the VR session.

Results posted on

2024-04-17

Participant Flow

Postpartum women with a history of anxiety (ANX) or depression (DEP) participated in a single virtual reality (VR) biofeedback session.

All women who were willing to participate received the same treatment arm, VR biofeedback session.

Participant milestones

Participant milestones
Measure
Virtual Reality Session
All participants in this study will complete a 1 hour virtual reality session. Flowly (TMC-CP01): The Flowly (TMC-CP01) treatment utilizes virtual reality and biofeedback to train patients to auto-regulate themselves and improve their pain/anxiety/depression.
Overall Study
STARTED
6
Overall Study
COMPLETED
6
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Virtual Reality Session
n=6 Participants
All participants in this study will complete a 1 hour virtual reality session. Flowly (TMC-CP01): The Flowly (TMC-CP01) treatment utilizes virtual reality and biofeedback to train patients to auto-regulate themselves and improve their pain/anxiety/depression.
Age, Categorical
<=18 years
0 Participants
n=6 Participants
Age, Categorical
Between 18 and 65 years
6 Participants
n=6 Participants
Age, Categorical
>=65 years
0 Participants
n=6 Participants
Age, Continuous
33.9 years
STANDARD_DEVIATION 4.9 • n=6 Participants
Sex: Female, Male
Female
6 Participants
n=6 Participants
Sex: Female, Male
Male
0 Participants
n=6 Participants
Region of Enrollment
United States
6 number of participants
n=6 Participants
Anxiety
42.3 units on a scale
STANDARD_DEVIATION 10.3 • n=6 Participants
Depression at baseline
6.3 units on a scale
STANDARD_DEVIATION 3.5 • n=6 Participants

PRIMARY outcome

Timeframe: Completed immediately after the VR session.

Population: postpartum women

Patient response to the feasibility of VR use. The question asked was, "I was able to do the session without difficulty," which was measured on a Likert Scale of 1-5. A score of 1 is indicative of great difficulty present and a score of 5 is indicative of no difficulty present. Outcome measurement is presented as an averaged score with standard deviation among participating patients.

Outcome measures

Outcome measures
Measure
Virtual Reality Session
n=6 Participants
All participants in this study will complete a 1 hour virtual reality session. Flowly (TMC-CP01): The Flowly (TMC-CP01) treatment utilizes virtual reality and biofeedback to train patients to auto-regulate themselves and improve their pain/anxiety/depression.
Intervention Feasibility
4.83 score on a scale
Standard Deviation 0.41

PRIMARY outcome

Timeframe: Completed directly after the VR intervention session and anxiety/depression measurements.

Population: postpartum women

Acceptability was assessed by questions, "Would you participate in another session?" Acceptability was measured by yes/no responses and reported as an overall percentage of participating patients who responded as yes.

Outcome measures

Outcome measures
Measure
Virtual Reality Session
n=6 Participants
All participants in this study will complete a 1 hour virtual reality session. Flowly (TMC-CP01): The Flowly (TMC-CP01) treatment utilizes virtual reality and biofeedback to train patients to auto-regulate themselves and improve their pain/anxiety/depression.
Intervention Acceptability
5 Participants

SECONDARY outcome

Timeframe: EPDS Completed directly before and after VR session.

Population: number of participants whose depression scores decreased.

Number of participants whose depression scores (as measured by Edinburgh Postnatal depression scale (EPDS)) decreased from baseline to post-VR intervention.

Outcome measures

Outcome measures
Measure
Virtual Reality Session
n=6 Participants
All participants in this study will complete a 1 hour virtual reality session. Flowly (TMC-CP01): The Flowly (TMC-CP01) treatment utilizes virtual reality and biofeedback to train patients to auto-regulate themselves and improve their pain/anxiety/depression.
Decrease in Depression From Baseline to Post-intervention
5 Participants

SECONDARY outcome

Timeframe: Completed directly before and after VR session.

Population: Number of participants with decreases in anxiety scores pre-post.

Number of participants whose anxiety scores (as measured by STAI) decreased from baseline to post-VR intervention.

Outcome measures

Outcome measures
Measure
Virtual Reality Session
n=6 Participants
All participants in this study will complete a 1 hour virtual reality session. Flowly (TMC-CP01): The Flowly (TMC-CP01) treatment utilizes virtual reality and biofeedback to train patients to auto-regulate themselves and improve their pain/anxiety/depression.
Decrease in State-Trait Anxiety Inventory (STAI) From Baseline to Post-intervention
5 Participants

Adverse Events

Virtual Reality Session

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Katherine Grace Lim

University of Pittsburgh Medical Center

Phone: 4126411777

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place