Immunity After COVID-19 Vaccination

NCT ID: NCT04924855

Last Updated: 2021-06-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-07-31

Study Completion Date

2022-08-01

Brief Summary

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The purpose of the research is to evaluate kinetic after vaccination to the COVID-19 coronavirus by measurements of specific and neutralizant antibodies for spike antigenic sequences .

This work will allow us to follow the efficacy and tolerance of the vaccine over a year, to evaluate the antibody profile, their kinetics, the fraction of neutralising antibodies and will also allow us to understand the attitudes to be taken to ensure the best protection for our staff

Detailed Description

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Our objective is to follow the hospital staff after vaccination, for this we will include two groups of participants:

G1: vaccinated staff who did not contract the virus (at the date of vaccination) and who had a serology \<0 at least at D7 of the date of vaccination dose 1 (known serological value) G2: vaccinated personnel who have contracted the virus with a PCR + and who have positive serology at least at D7 of the date of vaccination (known serological value)

Conditions

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Tunis Military Hospital Staff Vaccinated Against Covid 19

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Interventions

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Blood sampling (4 per year)

Blood sampling (4 per year)

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

RB-approved informed consent, age 18 years or older, male or female, anyone considering COVID-19 vaccination or anyone that has received COVID-19 vaccination.

Subjects can enroll at anytime after vaccination even though they may not have enrolled before vaccination.

Sampling Frequency and timing: Up to 8 total samples in 12 months -

Exclusion Criteria

Exclusion: Failure to provide informed consent

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Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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General Administration of Military Health, Tunisia

NETWORK

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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HMPIT vaccination committee

Tunis, Please Select..., Tunisia

Site Status RECRUITING

Countries

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Tunisia

Facility Contacts

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Nejla stambouli

Role: primary

Other Identifiers

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UR17DN05-3

Identifier Type: -

Identifier Source: org_study_id

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