Partner Notification of Sexually Transmitted Infections (STIs) in Testing Centers

NCT ID: NCT04921618

Last Updated: 2022-07-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

2200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-07-12

Study Completion Date

2022-12-31

Brief Summary

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Since the 2000s, the incidence of bacterial STIs increases, mainly among men who have sex with men but also among heterosexual men and women with multiple sexual partners. A partner notification (PN) approach could break transmission chains and curb STI epidemics. PN brings together a set of interventions to help people diagnosed with STIs to inform their partners, encourage them to get tested, so that they can access treatment or prevention. A PN approach, systematically offered at STI diagnosis, has not yet been implemented in France and needs to be evaluated. In 2018, the Conseil National du Sida (French National AIDS Council) stated in favor of a formalized PN approach, particularly in testing centers, which carry out a large part of STI diagnoses.

The aim of our research project is to build interventions facilitating information, testing and treatment of partners of people diagnosed with STIs in testing centers and sexual health clinics.

Step 1: A cross-sectional study

Primary objective

To describe the PN practices of people diagnosed with an STI in testing centers and sexual health clinics without any intervention

Secondary objectives

* To describe the profiles of people diagnosed with an STI in testing centers or sexual health clinics and therefore likely to receive an intervention to help them notify their partners;
* To describe the profiles of people notified by their partners and who attend testing centers or sexual health clinics for STI testing;
* To describe the notification received by these notified partners and identify the facilitators of testing use following notification.

Step 2: A qualitative study

Objectives

* To evaluate the acceptability of testing center staff for an STI notification program in general and discuss the feasibility of interventions pre-identified by a literature review;
* In a collaborative (researchers and staffs) approach, to adapt these interventions to (1) the testing centers working and (2) the needs of their users identified in the cross-sectional study.

Expected results

This study is the first step in implementation of a PN program as part of a comprehensive management of STI diagnoses in France.

Detailed Description

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Methods

Step 1: A cross-sectional study

Cross-sectional study conducted in testing centers and sexual health clinics (6 centers, 6 months of enrollment), targeting two populations:

* People aged 18 years or more diagnosed for at least one STI: the index patients;
* People aged 18 years or more attending the same centers for STI testing after being notified by a sexual partner: the notified partners.

This study is based on 3 online self-administered questionnaires:

* A questionnaire, the same for index patients and notified partners, collecting socio-demographic profile, health care and testing use, STI history and sexual behavior;
* A questionnaire for index patient on spontaneous PN practices of index patients one month after STI diagnosis, including types of partners notified, methods used to notify, and reasons for not notifying partners (this questionnaire will be sent one month after STI diagnosis to give participants the time to inform their partners);
* A questionnaire for notified partner on their experience of PN, such as the type of notifying partner, the methods and information transmitted during notification, their feelings and what led them to get testing after being notified.

A notified partner diagnosed with an STI will receive also the questionnaire on spontaneous practices of index patients at M1. This will allow us to observe whether people who had already been notified for an STI are more likely to notify their partners.

Step 2: A qualitative study

Focus-groups of 6-8 volunteers involved in STI testing in testing centers and sexual health clinics will be conducted based on an interview guide. Doctors and other staffs will be interviewed separately.

Thematic analysis

Conditions

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STI Hiv

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Index patients

People aged 18 or more diagnosed with \>= 1 STI in testing centers.

\[STI = bacterial STIs and/or HIV and/or acute hepatitis C virus (HCV)\]

2 online self-administered questionnaires on

Intervention Type OTHER

1. Participant profile
2. Spontaneous partner notification practices collected one month after STIs diagnosis

Notified partners

People aged 18 or more getting STI testing in testing centers after being notified by a sexual partner.

\[STI = bacterial STIs and/or HIV and/or acute HCV\]

2 online self-administered questionnaires on

Intervention Type OTHER

1. Participant profile
2. Experiences with partner notification and use of STI testing following notification

Interventions

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2 online self-administered questionnaires on

1. Participant profile
2. Spontaneous partner notification practices collected one month after STIs diagnosis

Intervention Type OTHER

2 online self-administered questionnaires on

1. Participant profile
2. Experiences with partner notification and use of STI testing following notification

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

For index patients

* Diagnosed with at least one bacterial STI, and/or HIV and/or acute HCV at one of the participating centers during the study period,
* Aged \>= 18,
* Agree to participate in the study after oral and written information.

For notified partners

* Attend one of the participating centers during the study period, within 6 months of being notified of their exposure to an STI (bacterial STI, and/or HIV and/or acute HCV) by one of their partners, who is infected with one or more of these STIs,
* Aged \>= 18,
* Agree to participate in the study after oral and written information.


For index patients and notified partners

* People who do not read or speak French,
* Wardship or curatorship adults.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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ANRS, Emerging Infectious Diseases

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jade Ghosn, Pr

Role: PRINCIPAL_INVESTIGATOR

IAME, Inserm UMR1137, Paris and Infectious diseases department, Bichat Hospital, Paris

Karen Champenois

Role: PRINCIPAL_INVESTIGATOR

IAME, Inserm UMR1137, Paris

Locations

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CeGIDD d'Aix-en-Provence

Aix-en-Provence, , France

Site Status RECRUITING

CeGIDD de Caen

Caen, , France

Site Status RECRUITING

CeGIDD de Lille

Lille, , France

Site Status RECRUITING

CeGIDD - La Joliette

Marseille, , France

Site Status RECRUITING

CeGIDD - Saint Adrien

Marseille, , France

Site Status RECRUITING

CeGIDD de Bichât

Paris, , France

Site Status RECRUITING

CeGIDD de La Pitié Salpêtrière

Paris, , France

Site Status RECRUITING

Centre de santé sexuelle - LE 190

Paris, , France

Site Status RECRUITING

Institut Alfred Fournier

Paris, , France

Site Status RECRUITING

Countries

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France

Facility Contacts

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Dominique AYMAR-MOULENE, Dr

Role: primary

04 13 31 84 69

Caroline GALIMARD, Dr

Role: primary

02 31 38 51 58

Laetitia RANDOUX, Dr

Role: primary

03 59 73 69 80

Julie SAULE, Dr

Role: primary

04 13 31 69 14

Jean-Luc ROBERT, Dr

Role: primary

04 13 31 56 78

Jade GHOSN, Pr

Role: primary

01 40 25 84 34

Gentiane MONSEL, Dr

Role: primary

01 42 17 70 12

Michel OHAYON, Dr

Role: primary

01 55 25 32 72

William TOSINI, Dr

Role: primary

01 40 78 26 00

Other Identifiers

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ANRS MIE Not'IST

Identifier Type: -

Identifier Source: org_study_id

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