Protocol for a Research Sample Repository for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries
NCT ID: NCT04920474
Last Updated: 2023-05-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
99999999 participants
OBSERVATIONAL
1991-07-31
2030-07-31
Brief Summary
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Representatives of participating centers and investigators or research groups may request access to research samples contained in the Research Sample Repository for the purpose of conducting research including:
* investigating molecular explanations for histocompatibility or clinical outcomes through analysis of genomic, epigenetic, or other biomolecular data
* evaluating the factors that affect transplant or cellular therapy outcome
* studying the distribution of HLA tissue types in different populations
* studying the success of transplantation, cellular therapies or supportive care in the management of marrow toxic injuries
* performing de-linked (anonymous) research
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Detailed Description
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* Hematopoietic Cell or other Cellular Therapy Donors
* Cord Blood Units
* Hematopoietic Cell Transplantation or other Cellular Therapy Recipients
* Patients with Marrow Toxic Injury
Conditions
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Study Design
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CASE_ONLY
RETROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
Cord Blood Units (CBUs)
* Testable material from CBUs (Specimens) infused at treatment centers covered under the C. W. Bill Young Transplantation Program are eligible for inclusion in the Research Sample Repository. Material may be submitted by participating treatment centers, centralized laboratories and Cord Blood Banks.
Hematopoietic Cell Transplantation or Other Cellular Therapy Recipients
* All U.S. recipients of allogeneic or autologous HC transplants or cellular therapies are eligible to participate in the Research Sample Repository. This includes adults with and without decision making capacity and children.
Patients with Marrow Toxic Injury
* Any patient who is treated for a marrow toxic injury at a center participating in the NMDP's Radiation Injury Treatment Network (RITN) is eligible to participate in the Research Sample Repository. This includes adults with and without decision-making capacity and children.
* Eligible patients may have received support care only, growth factor support, hematopoietic stem cell transplant or other appropriate medical treatment for marrow toxic injury
ALL
No
Sponsors
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Center for International Blood and Marrow Transplant Research
NETWORK
Responsible Party
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Principal Investigators
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Stephen Spellman
Role: PRINCIPAL_INVESTIGATOR
NMDP Be The Match/CIBMTR
Locations
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NMDP Biorepository
New Brighton, Minnesota, United States
Countries
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Central Contacts
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Facility Contacts
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Related Links
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Research Sample Repository Protocol
Other Identifiers
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NMDP IRB-1991-0002
Identifier Type: -
Identifier Source: org_study_id
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