Post-natal Post-traumatic Stress: Impact of an Early Dyadic Intervention Though Interaction Guidance Therapy on Maternal Sensitivity and Reduction of Maternal Stress

NCT ID: NCT04916938

Last Updated: 2022-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-12-29

Study Completion Date

2024-12-31

Brief Summary

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The aim of this study is to assess if an early therapeutic management focused on the mother-baby interaction using Interaction Guidance Therapy (IGT) with video feedback, brings an improvement of the maternal sensitivity in the interaction but also a decrease of the post-traumatic maternal symptoms.

Post Natal Post traumatic stress is known as a disorder that impaired maternal mental health but also development of motherhood and the construction of the bond to the baby through interactive disturbances.

The investigators will screen, among women who had a traumatic perception of an event related to the pregnancy or the childbirth, those who still present posttraumatic stress symptoms at 4 weeks post-partum. Four weeks from the traumatic event is the minimum delay to qualify a PTSD.

After randomization IGT versus Treatment As Usual (TAU), the investigators planned an early therapeutic intervention, 3 sessions at 8, 10 and 12 weeks of post-partum.

The investigators will assess the effect of the IGT on Maternal sensitivity and on the intensity of post-traumatic stress symptoms at 3 month post-partum and 1year.

Detailed Description

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The investigators will compare the efficacy of Interactive Guidance Therapy, a parent-infant psychotherapy using video feed back versus a dyadic treatment conduct as usual (TAU) in women who present a post traumatic stress disorder related to childbirth or pregnancy.

The main assessment is the maternal sensitivity, assessed during a video recorded free play interaction between the mother and the baby and rate with the Coding of interactive Behaviour (CIB).

This is a Single Blind Randomized clinical trial. Only the rating of the (CIB), which is the primary end point, will be done blind for the treatment the dyad received.

The randomization will proceed after the inclusion visit and the first assessment that take place at 6 weeks of post partum.

The following assessments will take place at 4 months and 12 months. The investigators will conduct a national multicentre study with 5 inclusions centres, which are all child psychiatry unit specialized in perinatal period and already train or in training for the IGT method.

* Pre-screening in post partum ward or during post partum consultation.
* Pre Inclusion at 5 (+-1) weeks to assess PTSD with Post traumatic checklist (PCL -5)
* Inclusion and First assessment at 6 weeks post partum
* Randomization: 3 session of IGT or TAU at 8 weeks, 10 weeks and 12 weeks Assessment at 4 months (+/-2W) and 12 months (+/- 1M)

Conditions

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Post-traumatic Stress Disorder (PTSD)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Interactive Guidance Therapy

Mother child psychotherapy based on video-feedback interaction after a free play session. The therapy usually enhances parent sensibility to the child.

Group Type EXPERIMENTAL

Interaction Guidance Therapy

Intervention Type BEHAVIORAL

Mother child psychotherapy based on video-feedback interaction after a free play session. The therapy usually enhances parent sensibility to the child.

Interview

Intervention Type BEHAVIORAL

History and perception of the mother's issues.

Self-rated questionnaires

Intervention Type BEHAVIORAL

Parental Self-Questionnaire to assess the perception of the evolution of the father, mother and child

Treatment as usual

Mother child psychotherapeutic sessions without video feed back.

Group Type ACTIVE_COMPARATOR

Mother's child psychotherapeutic session

Intervention Type BEHAVIORAL

Mother's representation of the event, mother's representation of the relation to her child, maternal emotions.

Interview

Intervention Type BEHAVIORAL

History and perception of the mother's issues.

Self-rated questionnaires

Intervention Type BEHAVIORAL

Parental Self-Questionnaire to assess the perception of the evolution of the father, mother and child

Interventions

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Interaction Guidance Therapy

Mother child psychotherapy based on video-feedback interaction after a free play session. The therapy usually enhances parent sensibility to the child.

Intervention Type BEHAVIORAL

Mother's child psychotherapeutic session

Mother's representation of the event, mother's representation of the relation to her child, maternal emotions.

Intervention Type BEHAVIORAL

Interview

History and perception of the mother's issues.

Intervention Type BEHAVIORAL

Self-rated questionnaires

Parental Self-Questionnaire to assess the perception of the evolution of the father, mother and child

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

For the mother:

1. Mother over 18 years old, who gave birth to a healthy child
2. Mother having a PCL-5 score higher than \> 31, 5 +/- 1 week after delivery and the traumatic event is related to childbirth or pregnancy.
3. Mother Speaking and reading French,
4. Mother with signed consent
5. Mother with rights open to social security
6. Mother and Father consent to the participation of the baby

For the father:

1. holder of parental authority
2. Speaking and reading French
3. Consent to self-reported questionnaires

Exclusion Criteria

1. PTSD not related to pregnancy or birth.
2. Child's health situation who impact the feasibility of the protocol, with a risk of hospitalization of more than 3 days between 6 and 12 weeks of life
3. Childbirth under 34 weeks of gestational age
4. Twins
5. Stillbirth
6. Any mother's acute, somatic or psychiatric clinical condition not compatible with the research procedure
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bérengère BEAUQUIER-MACCOTTA, MD

Role: PRINCIPAL_INVESTIGATOR

Assistance Publique - Hôpitaux de Paris

Locations

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CHU Besançon

Besançon, , France

Site Status RECRUITING

CHU - Maternité

Besançon, , France

Site Status NOT_YET_RECRUITING

Centre hospitalier Intercommunal André Grégoire

Montreuil, , France

Site Status NOT_YET_RECRUITING

Etablissement Ville Evrard

Noisy-le-Sec, , France

Site Status NOT_YET_RECRUITING

Centre hospitalier Saint Anne

Paris, , France

Site Status NOT_YET_RECRUITING

Hôpital Saint Joseph - Maternité

Paris, , France

Site Status NOT_YET_RECRUITING

Hôpital Necker - Enfants malades - pedospychiatrie

Paris, , France

Site Status RECRUITING

Hôpital Necker - Maternity

Paris, , France

Site Status NOT_YET_RECRUITING

CHRU Reims

Reims, , France

Site Status RECRUITING

Centre hospitalier - unité de périnalité

Reims, , France

Site Status NOT_YET_RECRUITING

Countries

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France

Central Contacts

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Bérengère BEAUQUIER-MACCOTTA, MD

Role: CONTACT

+33 6 62 17 62 92

Laure CHOUPEAUX, Master

Role: CONTACT

+33 1 44 38 17 11

Facility Contacts

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Lauriane VULLIEZ, MD, PhD

Role: primary

+33 3 81 21 81 54

Rajeev RAMANAH, MD, PhD

Role: primary

Bruno RENEVIER, MD

Role: primary

Bérengère BEAUQUIER-MACCOTTA, MD, PhD

Role: primary

+33 6 62 17 62 92

Romain DUGRAVIER, MD

Role: primary

+33 1 45 65 64 80

Elie AZRIA, MD, PhD

Role: primary

Lisa OUSS, MD

Role: primary

+33 1 44 49 45 61

Yves VILLE, MD, PhD

Role: primary

Julie AUER, MD

Role: primary

+33 3 82 24 15 15

Anne-catherine ROLLAND, MD, PhD

Role: primary

Other Identifiers

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ID-RCB Number

Identifier Type: OTHER

Identifier Source: secondary_id

APHP180615

Identifier Type: -

Identifier Source: org_study_id

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