Can Connected Devices Increase the Success Rate of Benzodiazepine Withdrawals in the Elderly?

NCT ID: NCT04912479

Last Updated: 2024-09-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-10-14

Study Completion Date

2026-02-01

Brief Summary

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This is a prospective randomized open study, which aims to evaluate the benefit of a connected watch to help people aged 65 years and older to withdraw from BZD over a six-month period, compared with classical withdrawal (e.g without connected watch). The study will include 100 patients, 50 in the control group and 50 in the intervention group.

Participants will be identified during a 12-month period through either external geriatric consultations or during a brief hospitalisation.

Detailed Description

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Despite a trivialized use of benzodiazepine (BZD) in elderly people (EP), long-term efficacy is often questioned, and treatment has to be regularly re-examined to avoid side effects. Typical intervention techniques to aid patients in reducing their dosage involve: providing information about BZD, explaining the risks associated with a chronic exposure, and tips for a successful withdrawal. In addition, the usage of a connected device may reinforce the patient's motivation by providing details on the quality of sleep and the number of steps taken (activity).

This is a prospective randomized open study, which aims to evaluate the benefit of a connected watch to help people aged 65 years and older to withdraw from BZD over a six-month period, compared with classical withdrawal (e.g without connected watch). The study will include 100 patients, 50 in the control group and 50 in the intervention group.

Participants will be identified during a 12-month period through either external geriatric consultations or during a brief hospitalisation.

Conditions

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Benzodiazepine Withdrawal

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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control

Patients will be given a plan to reduce progressively their dosage of Benzodiazepin every 2 weeks. Over a 6-month period they will receive a phone call from the hospital twice a month to reinforce their motivation.

Group Type NO_INTERVENTION

No interventions assigned to this group

intervention group

In addition to the progressive withdrawal of BZD, patients will be given a connected watch that provide them with information on their sleep quality and their performed activities. They will also receive a check-up phone call twice a month over a 6-month period.

Group Type EXPERIMENTAL

connected watch

Intervention Type DEVICE

connected watch that provide to patients with information on their sleep quality and their performed activities

Interventions

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connected watch

connected watch that provide to patients with information on their sleep quality and their performed activities

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Unassisted mobility (1/1 for the locomotion item on KATZ Activities of Daily Living scale)
* Mini-Mental State Examination (MMSE) ≥ 20
* With a daily consumption of benzodiazepine for more than 3 months
* Smartphone and/or tablet with internet connection

Exclusion Criteria

* Patient under legal protection
* Patient refuses to participate
* Patient does not speak French
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Toulouse

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Cécile McCambridge

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Toulouse

Locations

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University Hospital of Toulouse

Toulouse, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Cécile McCambridge, PharmD, PhD

Role: CONTACT

33-561776418

Facility Contacts

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Cécile McCambridge, PharmD, PhD

Role: primary

33-5 61 77 64 18

Other Identifiers

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2020-A02654-35

Identifier Type: OTHER

Identifier Source: secondary_id

RC31/19/0508

Identifier Type: -

Identifier Source: org_study_id

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