A User Study of the Soniflow System for Nasal Congestion Relief

NCT ID: NCT04910139

Last Updated: 2023-10-12

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-07-15

Study Completion Date

2021-01-26

Brief Summary

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The Soniflow System consists of an acoustic vibrational headband paired with a Smartphone App to provide rapid relief of nasal congestion.

Detailed Description

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The Soniflow System is a non-invasive device to provide rapid relief of nasal congestion. It consists of a headband with ultrasound transducers (hardware) coupled to a Smartphone application (software).

Conditions

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Nasal Congestion

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Treatment

Treatment using acoustic energy

Group Type EXPERIMENTAL

Soniflow System

Intervention Type DEVICE

Treatment using acoustic vibrational headband worn circumferentially at the level of the forehead paired with a Smartphone App.

Interventions

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Soniflow System

Treatment using acoustic vibrational headband worn circumferentially at the level of the forehead paired with a Smartphone App.

Intervention Type DEVICE

Other Intervention Names

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Soniflow System to provide nasal congestion relief

Eligibility Criteria

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Inclusion Criteria

1. Subject is \>18 years of age
2. Subject has had moderate to severe symptoms of nasal congestion for \>3 months (TNSS rating of 2 or 3)
3. Subject has signed IRB-approved informed consent form

Exclusion Criteria

1. Subject has neurologic comorbidities
2. Subject has active dental infection
3. Subject is pregnant
4. Subject has implanted intracranial electrostimulation device(s) (e.g. cochlear implant, deep brain stimulator)
5. Subject has undergone sinonasal or craniomaxillofacial surgery within the lats 3 months
6. Subject has been diagnosed with intracranial hemorrhage within the last 6 months
7. Subject has open scalp wounds or rashes
8. Subject has any history of craniotomy without replacement of a bone flap
9. Subject has elevated sensitivity to sound
10. Any physical condition that in the investigator's opinion would prevent adequate study participation or pose increased risk
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Third Wave Therapeutics

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jacob Johnson, MD

Role: PRINCIPAL_INVESTIGATOR

Principal Investigator

Locations

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San Francisco Otolaryngology Medical Group

San Francisco, California, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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CP-001

Identifier Type: -

Identifier Source: org_study_id

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