Trial Outcomes & Findings for CP1110 Sound Processor Feasibility (NCT NCT04898673)

NCT ID: NCT04898673

Last Updated: 2025-02-11

Results Overview

Paired difference in dB SRT between treatment and control, with their applicable noise reduction feature enabled. The speech recognition threshold (SRT) examines at which level the participant can repeat 50% of the speech material correctly. These scores may be negative or positive numeric values. Lower dB SRT scores indicate a better outcome.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

21 participants

Primary outcome timeframe

One day

Results posted on

2025-02-11

Participant Flow

21 subjects were recruited.

Participant milestones

Participant milestones
Measure
CP1000 Sound Processor Followed by the CP1110 Sound Processor
All study subjects were provided with a unique identifier. The ones that ended in an odd number were administered the CP1000 Sound Processor followed by the CP1110 Sound Processor.
CP1110 Sound Processor Followed by the CP1000 Sound Processor
All study subjects were provided with a unique identifier. The ones that ended in an even number were administered the CP1110 Sound Processor followed by the CP1000 Sound Processor.
Overall Study
STARTED
11
10
Overall Study
CP1110 Sound Processor
10
10
Overall Study
CP1000 Sound Processor
10
10
Overall Study
COMPLETED
10
10
Overall Study
NOT COMPLETED
1
0

Reasons for withdrawal

Reasons for withdrawal
Measure
CP1000 Sound Processor Followed by the CP1110 Sound Processor
All study subjects were provided with a unique identifier. The ones that ended in an odd number were administered the CP1000 Sound Processor followed by the CP1110 Sound Processor.
CP1110 Sound Processor Followed by the CP1000 Sound Processor
All study subjects were provided with a unique identifier. The ones that ended in an even number were administered the CP1110 Sound Processor followed by the CP1000 Sound Processor.
Overall Study
Screenfail
1
0

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
All Study Participants
n=20 Participants
Baseline characteristics are combined across the 2 arms.
Age, Customized
64.5 years
n=20 Participants
Sex: Female, Male
Female
13 Participants
n=20 Participants
Sex: Female, Male
Male
7 Participants
n=20 Participants
Region of Enrollment
Australia
20 participants
n=20 Participants

PRIMARY outcome

Timeframe: One day

Paired difference in dB SRT between treatment and control, with their applicable noise reduction feature enabled. The speech recognition threshold (SRT) examines at which level the participant can repeat 50% of the speech material correctly. These scores may be negative or positive numeric values. Lower dB SRT scores indicate a better outcome.

Outcome measures

Outcome measures
Measure
CP1000
n=20 Participants
All subjects tested using CP1000
CP1110
n=20 Participants
All subjects tested using CP1110
Speech Reception Thresholds (SRT) Assessed Via Sentence Scores in Spatially Separated Adaptive Noise
-6.07 decibels
Interval -6.07 to -4.47
-11.30 decibels
Interval -13.28 to -9.32

SECONDARY outcome

Timeframe: One day

Paired differences in percentage CNC Words correct in quiet (50 dB) between treatment and control, with various configurations of signal processing settings being enabled or disabled for each measure. Word recognition is a score of the number of words correctly repeated, expressed as a percentage. Higher percentage scores indicate a better outcome. Secondary Endpoint 1: CNC Words correct in quiet (50 dB) with both CP1000 and CP1110 sound processors using Signal-to-Noise Ratio - Noise Reduction (SNR-NR) turned on.

Outcome measures

Outcome measures
Measure
CP1000
n=20 Participants
All subjects tested using CP1000
CP1110
n=20 Participants
All subjects tested using CP1110
Percentage of Correct Words Assessed by CNC (Consonant Nucleus Consonant) Monosyllabic Word Scores in Quiet
57.5 percentage of correct words
Interval 51.67 to 63.33
58.10 percentage of correct words
Interval 51.56 to 64.64

SECONDARY outcome

Timeframe: One day

Paired differences in percentage CNC Words correct in quiet (50 dB) between treatment and control, with various configurations of signal processing settings being enabled or disabled for each measure. Word recognition is a score of the number of words correctly repeated, expressed as a percentage. Higher percentage scores indicate a better outcome. CNC Words in Quiet Score using both CP1110 and CP1000 sound processors Signal-to-Noise Ratio - Noise Reduction (SNR-NR) off with expander on.

Outcome measures

Outcome measures
Measure
CP1000
n=20 Participants
All subjects tested using CP1000
CP1110
n=20 Participants
All subjects tested using CP1110
Percentage of Correct Assessed by CNC (Consonant Nucleus Consonant) Monosyllabic Word Scores in Quiet
60.90 percentage of correct words
Interval 54.98 to 66.82
57.15 percentage of correct words
Interval 50.26 to 64.04

SECONDARY outcome

Timeframe: One Day

Paired differences in percentage CNC Words correct in quiet (50 dB) between treatment and control, with various configurations of signal processing settings being enabled or disabled for each measure. Word recognition is a score of the number of words correctly repeated, expressed as a percentage. Higher percentage scores indicate a better outcome. CNC Words in Quiet Score of CP1110 sound processor ForwardFocus ON (Moderate) vs CP1000 sound processor Signal-to-Noise Ration-Noise Reduction) On.

Outcome measures

Outcome measures
Measure
CP1000
n=20 Participants
All subjects tested using CP1000
CP1110
n=20 Participants
All subjects tested using CP1110
Percentage of Correct Words Assessed by CNC (Consonant Nucleus Consonant) Monosyllabic Word Scores in Quiet
57.50 percentage of correct words
Interval 51.67 to 63.33
56.35 percentage of correct words
Interval 50.33 to 62.37

Adverse Events

CP1000 Sound Processor

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

CP1110 Sound Processor

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

PRS Specialist, Clinical Affairs

Cochlear Limited

Phone: +61 2 9428 6555

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place