Preoperative and Postoperative Incentive Spirometry in Patients Undergoing Major Abdominal Surgery

NCT ID: NCT04887922

Last Updated: 2023-05-17

Study Results

Results available

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Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

2 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-05-03

Study Completion Date

2022-12-27

Brief Summary

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The goal of this study is to determine the efficacy of incentive spirometry (IS) to improve pulmonary function in the preoperative and postoperative surgical setting. The investigators hypothesize that IS will improve pulmonary function for patients undergoing major abdominal surgery when controlling for protocol compliance. Additionally, the investigators hypothesize that a digital IS device enabled with a text message-based mobile health intervention will improve pulmonary pre-habilitation and rehabilitation, as well as postoperative compliance with the IS device.

Detailed Description

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Conditions

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Abdominal Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

* Prior to surgery, participants will be randomized into three groups: (1) control group with no IS, (2) standard IS, and (3) digital IS + text message.
* Following surgery, patients will be re-randomized into two groups: (1) standard IS, and (2) digital IS + text message.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Pre-Surgery: No Incentive Spirometry (IS)

-Will not receive a incentive spirometer prior to surgery

Group Type NO_INTERVENTION

No interventions assigned to this group

Pre-Surgery: Standard Incentive Spirometry (IS)

* Will receive a conventional spirometer prior to surgery
* Will be asked to perform spirometry 30 times per day.

Group Type EXPERIMENTAL

Conventional spirometer

Intervention Type DEVICE

Will be provided to participants

Pre-Surgery: Digital Incentive Spirometry (IS) + Text Message

* Will receive the digital incentive spirometer (Spirobank G) that is compatible with health monitoring software developed by ZEPHYRx®. The digital spirometer couples with a HIPAA-compliant mobile application that calculates and stores pulmonary function test (PFT) results.
* Will be asked to perform spirometry 10 times per hour, every hour while awake, every day for at least 7 days prior to surgery. Absence of spirometry for 24 hours will trigger a text message reminder to encourage compliance with IS.

Group Type EXPERIMENTAL

MIR Spirobank G

Intervention Type DEVICE

FDA-approved, Bluetooth digital spirometer

ZEPHYRx®

Intervention Type DEVICE

ZEPHYRx® has developed a 1) digital Bluetooth-enabled IS that allows for the continuous and objective remote monitoring of patient compliance with pre- and postoperative IS via a smartphone app and online provider dashboard.

Post-Surgery: Standard Incentive Spirometry (IS)

* After surgery, the participants will receive a conventional spirometer.
* Will be instructed to perform spirometry 10 times per hour, every hour while awake through postoperative Day 3
* The conventional spirometer will be equipped with an accelerometer that will allow the research team to determine whether the spirometer moves throughout the patients' postoperative stay (as a proxy for IS use)

Group Type ACTIVE_COMPARATOR

Conventional spirometer

Intervention Type DEVICE

Will be provided to participants

Post-Surgery: Digital Incentive Spirometry (IS) + Text Message

* After surgery, the participants will receive the digital incentive spirometer (Spirobank G) that is compatible with health monitoring software developed by ZEPHYRx®. The digital spirometer couples with a HIPAA-compliant mobile application that calculates and stores pulmonary function test (PFT) results.
* Will be instructed to perform spirometry 10 times per hour, every hour while awake through postoperative Day 3
* Will receive text reminders to perform spirometry if they do not perform spirometry in a 24-hour period.

Group Type EXPERIMENTAL

MIR Spirobank G

Intervention Type DEVICE

FDA-approved, Bluetooth digital spirometer

ZEPHYRx®

Intervention Type DEVICE

ZEPHYRx® has developed a 1) digital Bluetooth-enabled IS that allows for the continuous and objective remote monitoring of patient compliance with pre- and postoperative IS via a smartphone app and online provider dashboard.

Interventions

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MIR Spirobank G

FDA-approved, Bluetooth digital spirometer

Intervention Type DEVICE

ZEPHYRx®

ZEPHYRx® has developed a 1) digital Bluetooth-enabled IS that allows for the continuous and objective remote monitoring of patient compliance with pre- and postoperative IS via a smartphone app and online provider dashboard.

Intervention Type DEVICE

Conventional spirometer

Will be provided to participants

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients scheduled to undergo major abdominal surgery with expected postoperative length of stay of 48 hours or more.
* Access to a smartphone.
* At least 18 years of age.
* Ability to understand and willingness to sign an IRB approved written informed consent document.

Exclusion Criteria

* Younger than 18 years of age
* No access to a smartphone
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Washington University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Chet Hammill, M.D., MCR

Role: PRINCIPAL_INVESTIGATOR

Washington University School of Medicine

Locations

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Washington University School of Medicine

St Louis, Missouri, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Related Links

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http://www.siteman.wustl.edu

Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine

Other Identifiers

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202105028

Identifier Type: -

Identifier Source: org_study_id

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