Evaluation of a Novel Female Hygiene Device for Postcoital Discomfort

NCT ID: NCT04885556

Last Updated: 2021-05-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-04-05

Study Completion Date

2021-09-15

Brief Summary

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Previous research has shown that semen deposition in the vagina after intercourse leads to dripping, discomfort, and vaginal odor. This study is evaluating a hygiene device designed to be inserted into the vagina after intercourse to absorb semen deposited into the vaginal canal to determine if there is a reduction in dripping and odor, and to determine the amount of fluids absorbed.

Detailed Description

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Despite the significant number of sexual dysfunctions in women, physicians often avoid discussing these concerns in the office setting. With recent research on the role of the pelvic floor, and recently approved medical therapies for hypoactive sexual desire disorder, physicians have begun to adapt to questioning patients about libido and pain-related sexual dysfunctions. However, pain-related sexual questionnaires often focus on insertional and penetrational dyspareunia, without asking about discomfort minutes, hours, or even the day following sexual intercourse. One common compliant in ambulatory sexual medicine clinics is the bothersome dripping, odor, and discomfort women experience after sexual activity when no condom is used, and when intravaginal ejaculation occurs.

Previous studies have shown the effects of semen on alterations in the vaginal flora. These changes contribute to a multitude of clinical complaints and diagnoses, including malodor, continuous discharge after intercourse, and bacterial vaginosis (BV). The exposure of semen changes the vaginal flora by increasing the pH levels, in turn altering the bacterial growth pattern. This implies the persistent presence of semen in the vagina may be one of the causes of malodor and development of BV. Chvapil utilized gas chromatography and demonstrated that the longer period of time semen was present in the vagina, the more likely it resulted in a strong and unattractive vaginal odor. Gallo showed that an incidental diagnosis of BV was correlated with detection of sperm on gram stain, and frequent coitus with or without condom use.

The investigator's goal in this study is to evaluate a novel postcoital consumer health product and its effects on the complaints of continuous seepage of semen and vaginal odor after intercourse.

Conditions

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Vaginal Discharge Dyspareunia Female Sexual Dysfunction Vaginitis Bacterial Vaginoses

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Subjects to be placed into one of two study groups, 1) immediate use and 2) 1 hour use
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Immediate Use

Subjects in this arm will be instructed to use the study device for 2 minutes and remove

Group Type EXPERIMENTAL

Tampon-like device for absorption of sexual fluids

Intervention Type DEVICE

Subjects will insert a tampon-like device to absorb sexual fluids after intercourse

1 hour use

Subjects in this arm will be instructed to use the product for one hour and then remove

Group Type EXPERIMENTAL

Tampon-like device for absorption of sexual fluids

Intervention Type DEVICE

Subjects will insert a tampon-like device to absorb sexual fluids after intercourse

Interventions

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Tampon-like device for absorption of sexual fluids

Subjects will insert a tampon-like device to absorb sexual fluids after intercourse

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Heterosexual
* Age 25-50
* Has used tampons in the past 5 years
* Sexually active (vaginal intercourse, minimum once per week)
* Answered "moderate" to "severe" to being bothered by dripping/discomfort on Patient Global Impression of Severity (PGI-S) questionnaire "on minutes, hours, or following day"
* Willing and able to use product
* Understands, reads, writes, and speaks English

Exclusion Criteria

* Pregnant
* Currently using condoms
* Unable to use device due to poor motor function
* Chronic disease which makes prone to infection (diabetes, autoimmune)
* Recurrent yeast infections
* Recurrent Urinary tract infection (UTI) (\>2 within the past year)
* Diagnosis of pelvic organ prolapse (Stage II or greater)
* Previous pelvic or vaginal surgery which, in the opinion of the investigator, may prevent proper use of product
* Unable to sign informed consent
Minimum Eligible Age

25 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Atlantic Health System

OTHER

Sponsor Role lead

Responsible Party

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Michael Ingber

Director of The Center for Specialized Women's Health, division of Garden State Urology/Atlantic Health System

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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The Center for Specialized Women's Health, division of Garden State Urology

Denville, New Jersey, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Cynthia Evaniecki

Role: CONTACT

973-537-5557

Facility Contacts

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Cynthia Evaniecki

Role: primary

973-537-5557

Role: backup

Other Identifiers

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AC-004

Identifier Type: -

Identifier Source: org_study_id

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