Systematic Symptom Identification With Disease Specific PROM to Assess Symptoms of Chronic GVHD in Outpatient Care in Patients Post HSCT

NCT ID: NCT04884204

Last Updated: 2023-11-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

35 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-04-30

Study Completion Date

2023-07-01

Brief Summary

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A two sited feasibility study to test the feasibility of systematic symptom identification with disease specific and clinically developed PROM (Lee Symptom Scale) longitudinally with a 12 month follow up in outpatient care in patients post HSCT to assess symptoms of chronic GVHD (n= 30).

Detailed Description

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A prospective, non-randomized, feasibility study examining a systematic approach to symptom management using PROMs with 12 months of follow up in hematological outpatient clinic

Conditions

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GVHD, Chronic Hematological Malignancy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Symptom management with Lee Symptom Scale

Participants will receive disease specific questionnaires electronically, cGVHD-PRO (Lee Symtpom Scale), one week prior to their scheduled visit in the outpatient clinic. The participants will be asked to answer the questionnaire from home without any involvement from clinicians. Afterwards the PRO data will be used during the scheduled clinical consultations as an instrument to discover symptoms on chronic GVHD and systematically to monitoring symptoms developing over time.

Group Type EXPERIMENTAL

Lee Symptom Scala

Intervention Type BEHAVIORAL

Symptom identification and management with Lee Symptom Scale in follow up care

Interventions

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Lee Symptom Scala

Symptom identification and management with Lee Symptom Scale in follow up care

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Adults \> 18 years old
* Approximately 3 months post HSCT (they will be included before HSCT, but the intervention will begin at 3 moths).
* Patients included needs to be able to manage a computer to receive and respond to collect PRO data.

Exclusion Criteria

* Patients who do not understand, read and speak Danish and/or have cognitive/psychiatric disorders not compatible with inclusion in a clinical study.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Novo Nordisk A/S

INDUSTRY

Sponsor Role collaborator

Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Mary Jarden

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mary Jarden

Role: PRINCIPAL_INVESTIGATOR

Rigshospitalet, Denmark

Locations

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Rigshospitalet

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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Copenhagen, Rigshospitalet

Identifier Type: -

Identifier Source: org_study_id