Trial Outcomes & Findings for Comparing Two Training Methods for Opioid Wizard (NCT NCT04867382)

Last Updated: 2022-12-15

Results Overview

Attitudes toward people with OUD were measured using the Difference, Disdain, and Blame scales, which measure attitudes toward people with mental illness and substance use disorders (SUDs). Difference, Disdain, and Blame scales measured stigma toward people with OUD, with three questions in each domain. Items are scored on a 9-point agreement scale. The range is 1-9; some items are reverse-scored. Items are averaged to obtain a score, with higher scores reflecting more stigma (range = 1-9). Evidence suggests that the scales demonstrate good internal consistency and are positively associated.

Recruitment status

COMPLETED

Study phase

Target enrollment

88 participants

Primary outcome timeframe

Immediately after completing online training.

Results posted on

2022-12-15

Participant Flow

Eligible participants for this study were primary care providers (PCCs) who practice at HealthPartners Clinics that were previously randomized into the intervention arm of the parent study (NCT04198428). Family physician, general internist or adult-care non-obstetric nurse practitioner or physician assistant were the titles included. PCCs were eligible to participate regardless of whether they were waivered to prescribe buprenorphine. 162 PCCs were invited by email to participate in this study.

A total of 411 Primary Care Clinicians (PCCs) actively practicing at clinics within the parent study were screened for eligibility. They were ineligible to participate if: * They had fewer than 5 eligible patient encounters between Sep 2020 and Feb 2021 (N=50); * They practiced in a non-intervention clinic (n=199)

Participant milestones

Participant milestones
Measure	Intervention The intervention arm received an online training in the use of the SDM tool that includes patient narratives and videos and person-first language.	Comparison Training The comparison training arm received an online training in the use of the SDM tool.
Overall Study STARTED	48	40
Overall Study Completed Stigma Reduction (Intervention) or Attention-control (Comparison) Training	48	40
Overall Study COMPLETED	46	39
Overall Study NOT COMPLETED	2	1

Reasons for withdrawal

Reasons for withdrawal
Measure	Intervention The intervention arm received an online training in the use of the SDM tool that includes patient narratives and videos and person-first language.	Comparison Training The comparison training arm received an online training in the use of the SDM tool.
Overall Study Did not complete the survey	2	1

Baseline Characteristics

Three participants completed the training but not the survey and we lack any demographic data on them.

Baseline characteristics by cohort

PRIMARY outcome

Timeframe: Immediately after completing online training.

Outcome measures

Outcome measures
Measure	Intervention n=46 Participants The intervention arm received an online training in the use of the SDM tool that includes patient narratives and videos and person-first language.	Comparison Training n=39 Participants The comparison training arm received an online training in the use of the SDM tool.
Difference, Disdain, and Blame Scales	4.1 score on a scale Standard Deviation 1.3	4.3 score on a scale Standard Deviation 1.2

SECONDARY outcome

Timeframe: Immediately after completing online training

Non-waivered PCCs rated one question on their intention to get waivered to prescribe buprenorphine ("How likely are you to get waivered to prescribe buprenorphine in the next year?") on a five-point Likert-type scale ranging from 1 (I definitely will not) to 5 (I definitely will). Higher scores correspond to greater intention to get waivered.

Outcome measures

Outcome measures
Measure	Intervention n=43 Participants The intervention arm received an online training in the use of the SDM tool that includes patient narratives and videos and person-first language.	Comparison Training n=34 Participants The comparison training arm received an online training in the use of the SDM tool.
Intentions to Get Waivered to Prescribe Buprenorphine.	2.3 score on a scale Standard Deviation 0.7	2.1 score on a scale Standard Deviation 0.8

SECONDARY outcome

Timeframe: Immediately after completing online training

Non-waivered PCCs rated one question on their intentions to prescribe buprenorphine if a waiver were no longer required ("If your patient with OUD requested buprenorphine in the next year and a waiver were no longer required, would you prescribe buprenorphine?") on a five-point Likert-type scale ranging from 1 (I definitely would not) to 5 (I definitely would). Higher numbers indicate greater likelihood to prescribe buprenorphine.

Outcome measures

Outcome measures
Measure	Intervention n=43 Participants The intervention arm received an online training in the use of the SDM tool that includes patient narratives and videos and person-first language.	Comparison Training n=34 Participants The comparison training arm received an online training in the use of the SDM tool.
Intentions to Prescribe Buprenorphine Should a Waiver no Longer be Required.	3.2 score on a scale Standard Deviation 1.0	3.0 score on a scale Standard Deviation 0.9

SECONDARY outcome

Timeframe: Six months following online training.

PCC Opioid Wizard use was defined as clicking within the tool, such as screening for OUD, making a diagnosis, providing a referral, prescribing a medication, printing patient education materials, or prescribing naloxone. This variable was dichotomized as whether the PCC ever clicked in the tool (1=yes; 0=no) in the 6 months following the training.

Outcome measures

Outcome measures
Measure	Intervention n=48 Participants The intervention arm received an online training in the use of the SDM tool that includes patient narratives and videos and person-first language.	Comparison Training n=40 Participants The comparison training arm received an online training in the use of the SDM tool.
Opioid Wizard Use	3 Participants	4 Participants

Adverse Events

Intervention

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Comparison Training

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Stephanie Hooker, PhD, MPH, MS, Principal Investigator

HealthPartners Institute

Phone: (952) 967-5056

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place

Measure	Intervention n=48 Participants The intervention arm received an online training in the use of the SDM tool that included patient narratives and videos and person-first language.	Comparison Training n=40 Participants The comparison training arm received an online training in the use of the SDM tool.	Total n=88 Participants Total of all reporting groups
Age, Categorical <=18 years	0 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	0 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	0 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Age, Categorical Between 18 and 65 years	40 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	34 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	74 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Age, Categorical >=65 years	6 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	5 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	11 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Age, Continuous	47.76 years STANDARD_DEVIATION 11.85 • n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	47.00 years STANDARD_DEVIATION 11.31 • n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	47.4 years STANDARD_DEVIATION 11.6 • n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Sex/Gender, Customized Male	17 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	14 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	31 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Sex/Gender, Customized Female	27 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	22 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	49 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Sex/Gender, Customized Not Listed	1 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	0 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	1 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Sex/Gender, Customized Prefer not to answer	1 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	3 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	4 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Race (NIH/OMB) American Indian or Alaska Native	0 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	0 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	0 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Race (NIH/OMB) Asian	6 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	2 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	8 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	0 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	0 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Race (NIH/OMB) Black or African American	3 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	3 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	6 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Race (NIH/OMB) White	29 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	28 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	57 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Race (NIH/OMB) More than one race	1 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	1 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	2 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Race (NIH/OMB) Unknown or Not Reported	7 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	5 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	12 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Region of Enrollment United States	48 participants n=48 Participants	40 participants n=40 Participants	88 participants n=88 Participants
Waivered to prescribe buprenorphine	3 Participants n=48 Participants	5 Participants n=40 Participants	8 Participants n=88 Participants
Type of provider degree Doctor of Medicine/Doctor of Osteopathic Medicine MD/DO	30 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	25 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	55 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.
Type of provider degree Physician Assistant/Nurse Practitioner PA/NP	16 Participants n=46 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	14 Participants n=39 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.	30 Participants n=85 Participants • Three participants completed the training but not the survey and we lack any demographic data on them.