A Study of A Novel Approach to Titrate Basal Insulin (LY2963016) in Participants With Type 2 Diabetes

NCT ID: NCT04864977

Last Updated: 2021-08-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

PHASE4

Study Classification

INTERVENTIONAL

Study Start Date

2021-08-16

Study Completion Date

2022-06-06

Brief Summary

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The main purpose of this study is to evaluate a novel approach for insulin glargine (LY2963016) titration for insulin-naïve adults with type 2 diabetes (T2D)

The study will last about 6 months.

Detailed Description

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Conditions

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Type 2 Diabetes Type 2 Diabetes Treated With Insulin

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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LY2963016

Participants with type 2 diabetes will be started on insulin glargine and dose will be titrated. Insulin glargine will be delivered via insulin pen each evening subcutaneously (SC). They will also check fasting blood glucose values on a study meter and prior to treating hypoglycemia. Participants will be asked to report the time and dose of their last administration.

Group Type EXPERIMENTAL

Basal Insulin

Intervention Type DRUG

Participants administered basal insulin

Interventions

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Basal Insulin

Participants administered basal insulin

Intervention Type DRUG

Other Intervention Names

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LY2963016

Eligibility Criteria

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Inclusion Criteria

* Adults with type 2 diabetes as diagnosed by endocrinologist
* No insulin over past 3 months
* Inadequate glycemic control with A1c ≥8.0% at or within 1 month prior to screening visit
* No history of diabetic ketoacidosis (DKA) or severe hypoglycemia leading to mental status change in the past 6 months
* Willingness and ability to follow the protocol including willingness to commence basal insulin, wear CGM, and communicate with healthcare provider.

Exclusion Criteria

* Contraindication to use of insulin glargine (e.g., allergy)
* Impaired recognition of hypoglycemia by the participant (as judged by the investigator)
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Eli Lilly and Company

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)

Role: STUDY_DIRECTOR

Eli Lilly and Company

Locations

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Boston Medical Center

Boston, Massachusetts, United States

Site Status

Countries

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United States

Related Links

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https://trials.lillytrialguide.com/en-US/trial/4QTvp0wrJ1GiK4youuzfmY

A Study of A Novel Approach to Titrate Basal Insulin (LY2963016) in Participants With Type 2 Diabetes

Other Identifiers

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I4L-MC-YCAA

Identifier Type: OTHER

Identifier Source: secondary_id

18095

Identifier Type: -

Identifier Source: org_study_id

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