Effects of Breathing Patterns on Post-prandial Vascular Function

NCT ID: NCT04864184

Last Updated: 2021-11-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

21 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-12-01

Study Completion Date

2021-09-30

Brief Summary

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The purpose of this study is investigate the effects of two different breathing styles on postprandial vascular function and oxidative stress markers. Participants will complete 2 breathing conditions in random order.

Detailed Description

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Conditions

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Healthy

Keywords

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Breathing Yogic breathing

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Each participant will complete 2 different sessions in random order.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Participants will be blinded to the respiratory rates being practiced during each study visit. Breathing patterns will be completed in random order.

Study Groups

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Breathing intervention

Participants will complete 2-minute breathing exercises following the Breathing App every 15 minutes during a 4-hour postprandial period following high-fat meal consumption.

Group Type EXPERIMENTAL

Normal physiologic rate breathing

Intervention Type BEHAVIORAL

2-minute breathing exercises will be completed every 15 minutes.

Slow breathing

Intervention Type BEHAVIORAL

2-minute breathing exercises will be completed every 15 minutes.

Interventions

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Normal physiologic rate breathing

2-minute breathing exercises will be completed every 15 minutes.

Intervention Type BEHAVIORAL

Slow breathing

2-minute breathing exercises will be completed every 15 minutes.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

• Male participants ages 18-35 years

Exclusion Criteria

* Infection within the previous 4 weeks
* Renal disorders
* Any cardiovascular disorders such as prior myocardial infarction, known coronary artery disease, personal history of stroke, heart failure, cardiac arrhythmias
* Chronic obstructive pulmonary disease
* Diabetes
* Inflammatory bowel disease
* HIV, rheumatoid arthritis, chronic or other inflammatory conditions
* Currently taking steroids or other anti-inflammatory medications
* Current use of nonsteroidal anti-inflammatory drugs
* Smoking
* Stage 2 hypertension or higher (systolic BP of 140 mm Hg or higher and/or diastolic BP of 90 mm Hg or higher)
* Lactose intolerance
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Texas State University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Cardiovascular Physiology Laboratory-Texas State University

San Marcos, Texas, United States

Site Status

Countries

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United States

References

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Hunter SD, Bernardi L, McAllister MJ, John D, Rahimi M, Lopez MR. Device-guided slow breathing alters postprandial oxidative stress in young adult males: A randomized sham-controlled crossover trial. Nutr Metab Cardiovasc Dis. 2023 Jan;33(1):203-209. doi: 10.1016/j.numecd.2022.10.002. Epub 2022 Oct 10.

Reference Type DERIVED
PMID: 36344308 (View on PubMed)

Other Identifiers

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7374

Identifier Type: -

Identifier Source: org_study_id