Understanding Ketamine's Dissociative Effects (KD Study)

NCT ID: NCT04861051

Last Updated: 2024-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE1

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-07-26

Study Completion Date

2028-08-01

Brief Summary

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The purpose of this study is to understand how ketamine brings about dissociative symptoms.

Detailed Description

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The goal of this proposed research is to record the effects of ketamine on brain activity to understand the changes that occur during dissociation in epilepsy patients with stereoEEG.

Conditions

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Epilepsy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Ketamine

Study participants will receive 0.5mg/kg of ketamine - one single infusion

Group Type OTHER

Ketamine

Intervention Type DRUG

Study participants will receive 0.5mg/kg of ketamine - one single infusion

Interventions

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Ketamine

Study participants will receive 0.5mg/kg of ketamine - one single infusion

Intervention Type DRUG

Other Intervention Names

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Ketalar

Eligibility Criteria

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Inclusion Criteria

* Patient in Stanford Epilepsy Monitoring Unit
* Age \>18 years old.

Exclusion Criteria

* Lifetime psychotic or bipolar disorder
* Inability to speak, read or understand English
* Pregnant or nursing females
* Prior adverse ketamine response
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Stanford University

OTHER

Sponsor Role lead

Responsible Party

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Karl Deisseroth

Professor of Bioengineering and of Psychiatry and Behavioral Sciences

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Karl Deisseroth, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Stanford University

Locations

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Stanford University School of Medicine

Palo Alto, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Arjay Cordero

Role: CONTACT

650-580-9000

Facility Contacts

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Karl Deisseroth, MD, PhD

Role: primary

Other Identifiers

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60085

Identifier Type: -

Identifier Source: org_study_id

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