EuroPainClinicsStudy X

NCT ID: NCT04855682

Last Updated: 2021-05-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

180 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-07-15

Study Completion Date

2024-04-15

Brief Summary

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Non-interventional, retrospective-prospective cohort study based on the collection of data and their evaluation after medical procedures: micro-discectomy, endoscopic discectomy, and hemilaminectomy.

Detailed Description

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The aim of this clinical study is to compare the benefits and complications after minimally invasive spinal procedures in patients with acute lumbosacral radicular syndrome caused by a herniated disc compressing the spinal neural structures.

The study only works with patient data provided by the outpatient clinic for research analysis in the EPCS IV clinical study. All patient data are encrypted during collection and evaluation during the study, and stored in an encrypted database. The data will be evaluated by an independent institution - The Institute of Measurement of the Slovak Academy of Sciences.

Conditions

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Back Pain

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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A

Endoscopic discectomy

Retrospective observation after 24 months after the spinal procedure

Intervention Type OTHER

Retrospective evaluation of patients before the procedure, and prospective evaluation of patients 24 months after the spinal procedure, comparing the MRI changes and procedure impact on fatty muscle degeneration process

Retrospective observation after 12 months after the spinal procedure

Intervention Type OTHER

Retrospective evaluation of the patient status before the procedure, and prospective evaluation of patients for 12 months after the spinal procedure, comparing the MRI changes

Prospective evaluation of patients after 12 and 24 months after the spinal procedure

Intervention Type OTHER

Prospective evaluation of patients after 12 and 24 months after the spinal procedure, comparing the MRI changes

B

Microdisectomy

Retrospective observation after 24 months after the spinal procedure

Intervention Type OTHER

Retrospective evaluation of patients before the procedure, and prospective evaluation of patients 24 months after the spinal procedure, comparing the MRI changes and procedure impact on fatty muscle degeneration process

Retrospective observation after 12 months after the spinal procedure

Intervention Type OTHER

Retrospective evaluation of the patient status before the procedure, and prospective evaluation of patients for 12 months after the spinal procedure, comparing the MRI changes

Prospective evaluation of patients after 12 and 24 months after the spinal procedure

Intervention Type OTHER

Prospective evaluation of patients after 12 and 24 months after the spinal procedure, comparing the MRI changes

C

Hemilaminectomy

Retrospective observation after 24 months after the spinal procedure

Intervention Type OTHER

Retrospective evaluation of patients before the procedure, and prospective evaluation of patients 24 months after the spinal procedure, comparing the MRI changes and procedure impact on fatty muscle degeneration process

Retrospective observation after 12 months after the spinal procedure

Intervention Type OTHER

Retrospective evaluation of the patient status before the procedure, and prospective evaluation of patients for 12 months after the spinal procedure, comparing the MRI changes

Prospective evaluation of patients after 12 and 24 months after the spinal procedure

Intervention Type OTHER

Prospective evaluation of patients after 12 and 24 months after the spinal procedure, comparing the MRI changes

Interventions

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Retrospective observation after 24 months after the spinal procedure

Retrospective evaluation of patients before the procedure, and prospective evaluation of patients 24 months after the spinal procedure, comparing the MRI changes and procedure impact on fatty muscle degeneration process

Intervention Type OTHER

Retrospective observation after 12 months after the spinal procedure

Retrospective evaluation of the patient status before the procedure, and prospective evaluation of patients for 12 months after the spinal procedure, comparing the MRI changes

Intervention Type OTHER

Prospective evaluation of patients after 12 and 24 months after the spinal procedure

Prospective evaluation of patients after 12 and 24 months after the spinal procedure, comparing the MRI changes

Intervention Type OTHER

Other Intervention Names

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Quality of life MRI description Quality of life MRI description Quality of life MRI description

Eligibility Criteria

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Inclusion Criteria

* patient age 18-60 years
* first spinal surgery in the areas L1-S1
* signed informed consent for the participation in the study

Exclusion Criteria

* patients with a history of other back problems (compression fracture, spondylitis, tumour)
* patients after repeated spinal surgeries
* patients with a systemic disease affecting the muscles elite athletes
* patients who disagree to participate in the study
* women with a positive pregnancy test or women planning on becoming pregnant
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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R-CLINIC s.r.o.

OTHER

Sponsor Role collaborator

Faculty Hospital Nitra

OTHER

Sponsor Role collaborator

Slovak Academy of Sciences

OTHER_GOV

Sponsor Role collaborator

University Hospital Bratislava

OTHER

Sponsor Role collaborator

Europainclinics z.ú.

OTHER

Sponsor Role lead

Responsible Party

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MUDr. Miroslav Buriánek MBA, MUDr. Robert Rapčan FIPP

Clinical Research Manager

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Miroslav Burianek, MD MBA

Role: STUDY_CHAIR

clinical monitor

Locations

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R - Clinic s.r.o.

Bardejov, , Slovakia

Site Status RECRUITING

R - Clinic s.r.o.

Bardejov, , Slovakia

Site Status NOT_YET_RECRUITING

R - Clinic s.r.o.

Bardejov, , Slovakia

Site Status RECRUITING

Countries

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Slovakia

Central Contacts

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Ladislav Kocan, MD PhD

Role: CONTACT

+421557891100

Robert Rapcan, MD PhD FIPP

Role: CONTACT

Facility Contacts

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Ladislav Kočan, MD PhD

Role: primary

Rapcan Robert, MD FIPP

Role: primary

+421 948 602 510

Robert Rapčan, MD FIPP

Role: primary

Miroslav Burianek, MD MBA

Role: backup

Other Identifiers

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4184/2021/ODDZ-11156

Identifier Type: -

Identifier Source: org_study_id

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