Menopause Sample Collection

NCT ID: NCT04853472

Last Updated: 2023-12-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

151 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-04-19

Study Completion Date

2023-03-01

Brief Summary

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This study will provide daily urine samples from women during early and late stage peri-menopause as well as post-menopause over the course of three calendar months in order to maintain the SPD sample bank.

Urine samples will be received in the clinical laboratory and aliquoted into 2.25ml amounts and stored at -80˚C until required.

Symptom information will also be recorded to determine whether there are any noticeable physiological changes that can be related to stage of the menopause.

Detailed Description

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Conditions

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Menopause

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Early Stage Peri-Menopause

Mild cycle irregularity over the last 3-6months (minimum), variation of \>6 days in length between consecutive cycles including shortened and longer cycles (but not \>60 days in length)

No interventions assigned to this group

Late Stage Peri-Menopause

Late stage peri-menopause: Irregular cycles with prolonged periods of amenorrhea \>60 days in length (but less than 12 months)

No interventions assigned to this group

Post-Menopause

Greater than 12 months since last menstrual period

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Female
* Between the ages of 45 and 60 years
* Suspects they are going through or have been through the menopause
* Experiencing cycle irregularities:

* Early Stage Peri-Menopause: Mild cycle irregularity over the last 3-6months (minimum), variation of \>6 days in length between consecutive cycles including shortened and longer cycles (but not \>60 days in length)
* Late stage peri-menopause: Irregular cycles with prolonged periods of amenorrhea \>60 days in length (but less than 12 months)
* Post-Menopause: Greater than 12 months since last menstrual period
* Willing to give informed consent

Exclusion Criteria

* Use of hormone replacement therapy (HRT)
* Use of hormone contraception
* Hysterectomy and/or oophorectomy
* Pregnant or breast feeding
* Other medical reason for amenorrhea (absence of menstruation)
Minimum Eligible Age

45 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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SPD Development Company Limited

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Raniero Zazzeroni

Role: STUDY_DIRECTOR

SPD Development Company

Jackie Boxer

Role: PRINCIPAL_INVESTIGATOR

SPD Development Company

Locations

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SPD Development Company Ltd

Bedford, Bedfordshire, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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PROTOCOL-1326

Identifier Type: -

Identifier Source: org_study_id